Patient Portal

Arun S. Varadhachary, MD, PhD

Associate Professor, Neurology
Division of Neuromuscular Disease

Specialty Areas

Neuromuscular Disease

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital
Missouri Baptist Medical Center

Areas of Clinical Interest

Autoimmune and inflammatory disorders of the central and peripheral nervous system, metabolic and degenerative neurologic disorders, neurologic manifestations of systemic disease

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-6981
Fax: 314-362-3752

Education

Education

Ph.D.: Immunology, Temple University School of Medicine, Philadelphia, Pennsylvania
Medical Degree: Temple University School of Medicine, Philadelphia, Pennsylvania
Fellowship: Neuromuscular Disease, Barnes-Jewish Hospital, St. Louis, MO 2010
Residency: Neurology, Barnes-Jewish Hospital, St. Louis, MO 2008

Publication & Research

Publication & Research

Clinical Problem-Solving: Fever and Rapidly Progressive Weakness in an Immunocompromised Patient.
Albertson AJ, Dietz AR, Younce JR, Varadhachary AS
Neurohospitalist. 2018 Oct; 8(4)194-198. doi: 10.1177/1941874418754966.

PMID:
    30245771
    [PubMed]
Related citations


Autoimmune Encephalitis With Multiple Autoantibodies: A Diagnostic and Therapeutic Challenge.
Kim AE, Kang P, Bucelli RC, Ferguson CJ, Schmidt RE, Varadhachary AS, Day GS
Neurologist. 2018 Mar; 23(2)55-59. doi: 10.1097/NRL.0000000000000171.

PMID:
    29494437
    [PubMed - indexed for MEDLINE]
Related citations


A 42-Year-Old Man with AIDS and Multiple Incomplete Ring Enhancing Lesions.
Kang P, Schmidt RE, Dahiya S, Varadhachary AS
Brain Pathol. 2017 Sep; 27(5)697-698. doi: 10.1111/bpa.12542.

PMID:
    28805005
    [PubMed - indexed for MEDLINE]
Related citations


In vivo kinetic approach reveals slow SOD1 turnover in the CNS.
Crisp MJ, Mawuenyega KG, Patterson BW, Reddy NC, Chott R, Self WK, Weihl CC, Jockel-Balsarotti J, Varadhachary AS, Bucelli RC, Yarasheski KE, Bateman RJ, Miller TM
J Clin Invest. 2015 Jul 1; 125(7)2772-80. doi: 10.1172/JCI80705.

PMID:
    26075819
    [PubMed - indexed for MEDLINE]
Related citations


Mitochondrial pathology in immune and inflammatory myopathies.
Varadhachary AS, Weihl CC, Pestronk A
Curr Opin Rheumatol. 2010 Nov; 22(6)651-7. doi: 10.1097/BOR.0b013e32833f108a.

PMID:
    20827203
    [PubMed - indexed for MEDLINE]
Related citations


Quantitation of "autophagic flux" in mature skeletal muscle.
Ju JS, Varadhachary AS, Miller SE, Weihl CC
Autophagy. 2010 Oct; 6(7)929-35. doi: 10.4161/auto.6.7.12785.

PMID:
    20657169
    [PubMed - indexed for MEDLINE]
Related citations


Atherosclerosis, antiphospholipid syndrome, and antiphospholipid antibodies.
Nicolo D, Varadhachary AS, Monestier M
Front Biosci. 2007 Jan 1; 122171-82.

PMID:
    17127454
    [PubMed - indexed for MEDLINE]
Related citations


Reciprocal induction of IL-10 and IL-12 from macrophages by low-density lipoprotein and its oxidized forms.
Varadhachary AS, Monestier M, Salgame P
Cell Immunol. 2001 Oct 10; 213(1)45-51.

PMID:
    11747355
    [PubMed - indexed for MEDLINE]
Related citations


Phosphatidylinositol 3'-kinase blocks CD95 aggregation and caspase-8 cleavage at the death-inducing signaling complex by modulating lateral diffusion of CD95.
Varadhachary AS, Edidin M, Hanlon AM, Peter ME, Krammer PH, Salgame P
J Immunol. 2001 Jun 1; 166(11)6564-9.

PMID:
    11359808
    [PubMed - indexed for MEDLINE]
Related citations


Selective up-regulation of phosphatidylinositol 3'-kinase activity in Th2 cells inhibits caspase-8 cleavage at the death-inducing complex: a mechanism for Th2 resistance from Fas-mediated apoptosis.
Varadhachary AS, Peter ME, Perdow SN, Krammer PH, Salgame P
J Immunol. 1999 Nov 1; 163(9)4772-9.

PMID:
    10528176
    [PubMed - indexed for MEDLINE]
Related citations


CD95 mediated T cell apoptosis and its relevance to immune deviation.
Varadhachary AS, Salgame P
Oncogene. 1998 Dec 24; 17(25)3271-6.

PMID:
    9916989
    [PubMed - indexed for MEDLINE]
Related citations


Differential ability of T cell subsets to undergo activation-induced cell death.
Varadhachary AS, Perdow SN, Hu C, Ramanarayanan M, Salgame P
Proc Natl Acad Sci U S A. 1997 May 27; 94(11)5778-83.

PMID:
    9159150
    [PubMed - indexed for MEDLINE]
Related citations


An ELISA for detection of apoptosis.
Salgame P, Varadhachary AS, Primiano LL, Fincke JE, Muller S, Monestier M
Nucleic Acids Res. 1997 Feb 1; 25(3)680-1.

PMID:
    9016614
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Current research explores the interaction between autoimmune/inflammatory disorders and mitochondrial  dysfunction with particular focus on dermatomyositis.