Patient Portal

Anne Maureen Connolly, MD

Professor, Neurology
Division of Pediatric Neurology
Professor, Pediatrics

Specialty Areas

Pediatric Neurology
Neuromuscular Disease
Nerve Disorders
Muscle Disorders
Muscular Dystrophy
ALS - Lou Gehrig's Disease
Myasthenia Gravis
Electromyography

Board Certifications

EMG
Pediatrics
Pediatric Neurology

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Childhood chronic demyelinating polyneuropathy, Duchenne muscular dystrophy, congenital muscular dystrophy syndromes, brachial plexus injury, myotonia congenita, childhood opsoclonus-myoclonus, spiral muscularatrophy, childhood myasthenia gravis, myasthenic syndrome, childhood neuropathy, childhood electromyography, neuromuscular disease, electromyography, electrodiagnostic studies,, nerve disorders.

  • Maps & Directions
  • Education
  • Publication & Research
  • Videos

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite D
Office Phone: 314-454-6120
Fax: 314-454-2523

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-6981
Fax: 314-362-3752
Email: connolly@kids.wustl.edu

Education

Education

Fellowship: Child Neurology, St. Louis Children's Hospital, St. Louis, Missouri 1990
Residency: Neurology, Barnes Hospital/Washington University School of Medicine, St. Louis, Missouri 1988
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1987
Medical Degree: Indiana University, Indianapolis, Indiana 1984
B.S.: Saint Mary's College, Notre Dame, Indiana 1980

Publication & Research

Publication & Research

Longitudinal pulmonary function testing outcome measures in Duchenne muscular dystrophy: Long-term natural history with and without glucocorticoids.
McDonald CM, Gordish-Dressman H, Henricson EK, Duong T, Joyce NC, Jhawar S, Leinonen M, Hsu F, Connolly AM, Cnaan A, Abresch RT, CINRG investigators for PubMed.
Neuromuscul Disord. 2018 Aug 29; pii: S0960-8966(18)30043-9. doi: 10.1016/j.nmd.2018.07.004.

PMID:
    30336970
    [PubMed - as supplied by publisher]
Related citations


Recruitment & retention program for the NeuroNEXT SMA Biomarker Study: Super Babies for SMA!
Bartlett A, Kolb SJ, Kingsley A, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Coffey CS, Yankey JW, Cudkowicz ME, McGovern MM, McNeil DE, Arnold WD, Kissel JT, NeuroNEXT Clinical Trial Network and on behalf of the NN101 SMA Biomarker Investigators.
Contemp Clin Trials Commun. 2018 Sep; 11113-119. doi: 10.1016/j.conctc.2018.07.002.

PMID:
    30094386
    [PubMed]
Related citations


Needs assessment survey of obstetrics and gynecology subspecialty fellowship program directors.
Botros SM, Learman LA, Bell C, Connolly AM, Schindler N, Kenton K
Am J Obstet Gynecol. 2018 Aug; 219(2)207-208. doi: 10.1016/j.ajog.2018.04.038.

PMID:
    29705192
    [PubMed - in process]
Related citations


Congenital Titinopathy: Comprehensive characterization and pathogenic insights.
Oates EC, Jones KJ, Donkervoort S, Charlton A, Brammah S, Smith JE 3rd, Ware JS, Yau KS, Swanson LC, Whiffin N, Peduto AJ, Bournazos A, Waddell LB, Farrar MA, Sampaio HA, Teoh HL, Lamont PJ, Mowat D, Fitzsimons RB, Corbett AJ, Ryan MM, O'Grady GL, Sandaradura SA, Ghaoui R, Joshi H, Marshall JL, Nolan MA, Kaur S, Punetha J, Töpf A, Harris E, Bakshi M, Genetti CA, Marttila M, Werlauff U, Streichenberger N, Pestronk A, Mazanti I, Pinner JR, Vuillerot C, Grosmann C, Camacho A, Mohassel P, Leach ME, Foley AR, Bharucha-Goebel D, Collins J, Connolly AM, Gilbreath HR, Iannaccone ST, Castro D, Cummings BB, Webster RI, Lazaro L, Vissing J, Coppens S, Deconinck N, Luk HM, Thomas NH, Foulds NC, Illingworth MA, Ellard S, McLean CA, Phadke R, Ravenscroft G, Witting N, Hackman P, Richard I, Cooper ST, Kamsteeg EJ, Hoffman EP, Bushby K, Straub V, Udd B, Ferreiro A, North KN, Clarke NF, Lek M, Beggs AH, Bönnemann CG, MacArthur DG, Granzier H, Davis MR, Laing NG
Ann Neurol. 2018 Jun; 83(6)1105-1124. doi: 10.1002/ana.25241.

PMID:
    29691892
    [PubMed - in process]
Related citations


Putting the public (back) into public health: leadership, evidence and action.
South J, Connolly AM, Stansfield JA, Johnstone P, Henderson G, Fenton KA
J Public Health (Oxf). 2018 Mar 13; doi: 10.1093/pubmed/fdy041.

PMID:
    29546426
    [PubMed - as supplied by publisher]
Related citations


A multinational study on motor function in early-onset FSHD.
Mah JK, Feng J, Jacobs MB, Duong T, Carroll K, de Valle K, Carty CL, Morgenroth LP, Guglieri M, Ryan MM, Clemens PR, Thangarajh M, Webster R, Smith E, Connolly AM, McDonald CM, Karachunski P, Tulinius M, Harper A, Cnaan A, Chen YW, Cooperative International Neuromuscular Research Group (CINRG) Investigators.
Neurology. 2018 Apr 10; 90(15)e1333-e1338. doi: 10.1212/WNL.0000000000005297.

PMID:
    29540582
    [PubMed - in process]
Related citations


Nusinersen versus Sham Control in Later-Onset Spinal Muscular Atrophy.
Mercuri E, Darras BT, Chiriboga CA, Day JW, Campbell C, Connolly AM, Iannaccone ST, Kirschner J, Kuntz NL, Saito K, Shieh PB, Tulinius M, Mazzone ES, Montes J, Bishop KM, Yang Q, Foster R, Gheuens S, Bennett CF, Farwell W, Schneider E, De Vivo DC, Finkel RS, CHERISH Study Group.
N Engl J Med. 2018 Feb 15; 378(7)625-635. doi: 10.1056/NEJMoa1710504.

PMID:
    29443664
    [PubMed - indexed for MEDLINE]
Related citations


Long-term effects of glucocorticoids on function, quality of life, and survival in patients with Duchenne muscular dystrophy: a prospective cohort study.
McDonald CM, Henricson EK, Abresch RT, Duong T, Joyce NC, Hu F, Clemens PR, Hoffman EP, Cnaan A, Gordish-Dressman H, CINRG Investigators.
Lancet. 2018 Feb 3; 391(10119)451-461. doi: 10.1016/S0140-6736(17)32160-8.

PMID:
    29174484
    [PubMed - indexed for MEDLINE]
Related citations


Natural history of infantile-onset spinal muscular atrophy.
Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Iannaccone ST, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AHM, Bartlett A, Kissel JT, NeuroNEXT Clinical Trial Network on behalf of the NN101 SMA Biomarker Investigators.
Ann Neurol. 2017 Dec; 82(6)883-891. doi: 10.1002/ana.25101.

PMID:
    29149772
    [PubMed - indexed for MEDLINE]
Related citations


Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy.
Finkel RS, Mercuri E, Darras BT, Connolly AM, Kuntz NL, Kirschner J, Chiriboga CA, Saito K, Servais L, Tizzano E, Topaloglu H, Tulinius M, Montes J, Glanzman AM, Bishop K, Zhong ZJ, Gheuens S, Bennett CF, Schneider E, Farwell W, De Vivo DC, ENDEAR Study Group.
N Engl J Med. 2017 Nov 2; 377(18)1723-1732. doi: 10.1056/NEJMoa1702752.

PMID:
    29091570
    [PubMed - indexed for MEDLINE]
Related citations


Pulmonary Endpoints in Duchenne Muscular Dystrophy. A Workshop Summary.
Finder J, Mayer OH, Sheehan D, Sawnani H, Abresch RT, Benditt J, Birnkrant DJ, Duong T, Henricson E, Kinnett K, McDonald CM, Connolly AM
Am J Respir Crit Care Med. 2017 Aug 15; 196(4)512-519. doi: 10.1164/rccm.201703-0507WS.

PMID:
    28636407
    [PubMed - indexed for MEDLINE]
Related citations


<i>PMP22</i> exon 4 deletion causes ER retention of PMP22 and a gain-of-function allele in CMT1E.
Wang DS, Wu X, Bai Y, Zaidman C, Grider T, Kamholz J, Lupski JR, Connolly AM, Shy ME
Ann Clin Transl Neurol. 2017 Apr; 4(4)236-245. doi: 10.1002/acn3.395.

PMID:
    28382305
    [PubMed]
Related citations


Comments on Letter to the Editor entitled: "Role of electrophysiological evaluation for the best device choice to prevent sudden cardiac death in patients with Myotonic Dystrophy Type1 and Emery Dreifuss Muscular Dystrophy".
Sommerville RB, Vincenti MG, Winborn K, Casey A, Stitziel NO, Connolly AM, Mann DL
Trends Cardiovasc Med. 2017 Feb 7; pii: S1050-1738(17)30014-2. doi: 10.1016/j.tcm.2017.02.002.

PMID:
    28291654
    [PubMed - as supplied by publisher]
Related citations


Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency.
Lovric S, Goncalves S, Gee HY, Oskouian B, Srinivas H, Choi WI, Shril S, Ashraf S, Tan W, Rao J, Airik M, Schapiro D, Braun DA, Sadowski CE, Widmeier E, Jobst-Schwan T, Schmidt JM, Girik V, Capitani G, Suh JH, Lachaussée N, Arrondel C, Patat J, Gribouval O, Furlano M, Boyer O, Schmitt A, Vuiblet V, Hashmi S, Wilcken R, Bernier FP, Innes AM, Parboosingh JS, Lamont RE, Midgley JP, Wright N, Majewski J, Zenker M, Schaefer F, Kuss N, Greil J, Giese T, Schwarz K, Catheline V, Schanze D, Franke I, Sznajer Y, Truant AS, Adams B, Désir J, Biemann R, Pei Y, Ars E, Lloberas N, Madrid A, Dharnidharka VR, Connolly AM, Willing MC, Cooper MA, Lifton RP, Simons M, Riezman H, Antignac C, Saba JD, Hildebrandt F
J Clin Invest. 2017 Mar 1; 127(3)912-928. doi: 10.1172/JCI89626.

PMID:
    28165339
    [PubMed - indexed for MEDLINE]
Related citations


Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy.
Hogarth MW, Houweling PJ, Thomas KC, Gordish-Dressman H, Bello L, Cooperative International Neuromuscular Research Group (CINRG)., Pegoraro E, Hoffman EP, Head SI, North KN
Nat Commun. 2017 Jan 31; 814143. doi: 10.1038/ncomms14143.

PMID:
    28139640
    [PubMed - in process]
Related citations


Tracking diaphragm movement by using ultrasound to assess its strength.
Connolly AM, Mittendorfer B
J Physiol. 2016 Dec 15; 594(24)7147-7148. doi: 10.1113/JP273313.

PMID:
    27976400
    [PubMed - indexed for MEDLINE]
Related citations


Association Study of Exon Variants in the NF-κB and TGFβ Pathways Identifies CD40 as a Modifier of Duchenne Muscular Dystrophy.
Bello L, Flanigan KM, Weiss RB, United Dystrophinopathy Project., Spitali P, Aartsma-Rus A, Muntoni F, Zaharieva I, Ferlini A, Mercuri E, Tuffery-Giraud S, Claustres M, Straub V, Lochmüller H, Barp A, Vianello S, Pegoraro E, Punetha J, Gordish-Dressman H, Giri M, McDonald CM, Hoffman EP, Cooperative International Neuromuscular Research Group.
Am J Hum Genet. 2016 Nov 3; 99(5)1163-1171. doi: 10.1016/j.ajhg.2016.08.023.

PMID:
    27745838
    [PubMed - indexed for MEDLINE]
Related citations


Baseline Understanding of Urinary Incontinence (UI) and Prolapse (POP) in New FPMRS Patients: Is There an Age-Related Difference?
Davidson E, Myers EM, De La Cruz JF, Connolly AM
J Minim Invasive Gynecol. 2015 Nov-Dec; 22(6S)S64-S65. doi: 10.1016/j.jmig.2015.08.172.

PMID:
    27679299
    [PubMed - as supplied by publisher]
Related citations


Evaluation of an E-learning resource on approach to the first unprovoked seizure.
Le Marne FA, McGinness H, Slade R, Cardamone M, Balbir Singh S, Connolly AM, Bye AM
J Paediatr Child Health. 2016 Sep; 52(9)896-900. doi: 10.1111/jpc.13277.

PMID:
    27650145
    [PubMed - indexed for MEDLINE]
Related citations


Diagnosis and management of adult hereditary cardio-neuromuscular disorders: A model for the multidisciplinary care of complex genetic disorders.
Sommerville RB, Vincenti MG, Winborn K, Casey A, Stitziel NO, Connolly AM, Mann DL
Trends Cardiovasc Med. 2017 Jan; 27(1)51-58. doi: 10.1016/j.tcm.2016.06.005.

PMID:
    27452966
    [PubMed - indexed for MEDLINE]
Related citations

Videos

Videos