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Faculty Physicians

Anne Maureen Connolly, MD

Professor, Neurology
Division of Pediatric Neurology
Professor, Pediatrics

Specialty Areas

Pediatric Neurology
Neuromuscular Disease
Nerve Disorders
Muscle Disorders
Muscular Dystrophy
ALS - Lou Gehrig's Disease
Myasthenia Gravis
Electromyography

Board Certifications

EMG
Pediatrics
Pediatric Neurology

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Childhood chronic demyelinating polyneuropathy, Duchenne muscular dystrophy, congenital muscular dystrophy syndromes, brachial plexus injury, myotonia congenita, childhood opsoclonus-myoclonus, spiral muscularatrophy, childhood myasthenia gravis, myasthenic syndrome, childhood neuropathy, childhood electromyography, neuromuscular disease, electromyography, electrodiagnostic studies,, nerve disorders.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Suite D
Office Phone: 314-454-6120
Fax: 314-454-2523

Center for Advanced Medicine
Neuroscience Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 6
Office Phone: 314-362-6981
Fax: 314-362-3752
Email: connolly@kids.wustl.edu

Education

Education

Fellowship: Child Neurology, St. Louis Children's Hospital, St. Louis, Missouri 1990
Residency: Neurology, Barnes Hospital/Washington University School of Medicine, St. Louis, Missouri 1988
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri 1987
Medical Degree: Indiana University, Indianapolis, Indiana 1984
B.S.: Saint Mary's College, Notre Dame, Indiana 1980

Publication & Research

Publication & Research

A recurrent de novo CTBP1 mutation is associated with developmental delay, hypotonia, ataxia, and tooth enamel defects.
Beck DB, Cho MT, Millan F, Yates C, Hannibal M, O'Connor B, Shinawi M, Connolly AM, Waggoner D, Halbach S, Angle B, Sanders V, Shen Y, Retterer K, Begtrup A, Bai R, Chung WK
Neurogenetics. 2016 Apr 19;

PMID:
    27094857
    [PubMed - as supplied by publisher]
Related citations


Clinical trial readiness in non-ambulatory boys and men with DMD: MDA-DMD network follow-up.
Connolly AM, Florence JM, Zaidman CM, Golumbek PT, Mendell JR, Flanigan KM, Karachunski PI, Day JW, McDonald CM, Darras BT, Kang PB, Siener CA, Gadeken RK, Anand P, Schierbecker JR, Malkus EC, Lowes LP, Alfano LN, Johnson L, Nicorici A, Kelecic JM, Quigley J, Pasternak AE, Miller JP, MDA DMD Clinical Research Network
Muscle Nerve. 2016 Mar 1; doi: 10.1002/mus.25089.

PMID:
    26930423
    [PubMed - as supplied by publisher]
Related citations


Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.
Kolb SJ, Coffey CS, Yankey JW, Krosschell K, Arnold WD, Rutkove SB, Swoboda KJ, Reyna SP, Sakonju A, Darras BT, Shell R, Kuntz N, Castro D, Iannaccone ST, Parsons J, Connolly AM, Chiriboga CA, McDonald C, Burnette WB, Werner K, Thangarajh M, Shieh PB, Finanger E, Cudkowicz ME, McGovern MM, McNeil DE, Finkel R, Kaye E, Kingsley A, Renusch SR, McGovern VL, Wang X, Zaworski PG, Prior TW, Burghes AH, Bartlett A, Kissel JT, NeuroNEXT Clinical Trial Network and on behalf of the NN101 SMA Biomarker Investigators
Ann Clin Transl Neurol. 2016 Feb; 3(2)132-45. doi: 10.1002/acn3.283.

PMID:
    26900585
    [PubMed]
Related citations


The Severity of Gliosis in Hippocampal Sclerosis Correlates with Pre-Operative Seizure Burden and Outcome After Temporal Lobectomy.
Johnson AM, Sugo E, Barreto D, Hiew CC, Lawson JA, Connolly AM, Somerville E, Hasic E, Bye AM, Cunningham AM
Mol Neurobiol. 2015 Oct 9;

PMID:
    26452360
    [PubMed - as supplied by publisher]
Related citations


Quantitative muscle ultrasound measures rapid declines over time in children with SMA type 1.
Ng KW, Connolly AM, Zaidman CM
J Neurol Sci. 2015 Nov 15; 358(1-2)178-82. doi: 10.1016/j.jns.2015.08.1532.

PMID:
    26432577
    [PubMed - in process]
Related citations


Rhabdomyolysis-Associated Mutations in Human LPIN1 Lead to Loss of Phosphatidic Acid Phosphohydrolase Activity.
Schweitzer GG, Collier SL, Chen Z, Eaton JM, Connolly AM, Bucelli RC, Pestronk A, Harris TE, Finck BN
JIMD Rep. 2015; 23113-22. doi: 10.1007/8904_2015_440.

PMID:
    25967228
    [PubMed]
Related citations


Feasibility and Reproducibility of Echocardiographic Measures in Children with Muscular Dystrophies.
Spurney CF, McCaffrey FM, Cnaan A, Morgenroth LP, Ghelani SJ, Gordish-Dressman H, Arrieta A, Connolly AM, Lotze TE, McDonald CM, Leshner RT, Clemens PR
J Am Soc Echocardiogr. 2015 Aug; 28(8)999-1008. doi: 10.1016/j.echo.2015.03.003.

PMID:
    25906753
    [PubMed - indexed for MEDLINE]
Related citations


Muscle ultrasound quantifies disease progression over time in infants and young boys with duchenne muscular dystrophy.
Zaidman CM, Malkus EC, Connolly AM
Muscle Nerve. 2015 Sep; 52(3)334-8. doi: 10.1002/mus.24609.

PMID:
    25704979
    [PubMed - indexed for MEDLINE]
Related citations


Electrical impedance myography in Duchenne muscular dystrophy and healthy controls: A multicenter study of reliability and validity.
Zaidman CM, Wang LL, Connolly AM, Florence J, Wong BL, Parsons JA, Apkon S, Goyal N, Williams E, Escolar D, Rutkove SB, Bohorquez JL, DART-EIM Clinical Evaluators Consortium
Muscle Nerve. 2015 Oct; 52(4)592-7. doi: 10.1002/mus.24611.

PMID:
    25702806
    [PubMed - indexed for MEDLINE]
Related citations


Novel mutations expand the clinical spectrum of DYNC1H1-associated spinal muscular atrophy.
Scoto M, Rossor AM, Harms MB, Cirak S, Calissano M, Robb S, Manzur AY, Martínez Arroyo A, Rodriguez Sanz A, Mansour S, Fallon P, Hadjikoumi I, Klein A, Yang M, De Visser M, Overweg-Plandsoen WC, Baas F, Taylor JP, Benatar M, Connolly AM, Al-Lozi MT, Nixon J, de Goede CG, Foley AR, Mcwilliam C, Pitt M, Sewry C, Phadke R, Hafezparast M, Chong WK, Mercuri E, Baloh RH, Reilly MM, Muntoni F
Neurology. 2015 Feb 17; 84(7)668-79. doi: 10.1212/WNL.0000000000001269.

PMID:
    25609763
    [PubMed - indexed for MEDLINE]
Related citations


Exploring carer perceptions of training in out-of-hospital use of buccal midazolam for emergency management of seizures (2008-2012).
Connolly AM, Beavis E, Mugica-Cox B, Bye AM, Lawson JA
J Paediatr Child Health. 2015 Jul; 51(7)704-7. doi: 10.1111/jpc.12811.

PMID:
    25594133
    [PubMed - indexed for MEDLINE]
Related citations


Response to "About focal cortical dysplasia (FCD) type IIIa".
Johnson AM, Sugo E, Barreto D, Cunningham AM, Hiew CC, Lawson JA, Somerville ER, Connolly AM, Bye AM
Epilepsy Res. 2014 Dec; 108(10)1958-9. doi: 10.1016/j.eplepsyres.2014.09.027.

PMID:
    25449364
    [PubMed - indexed for MEDLINE]
Related citations


Outcome reliability in non-ambulatory boys/men with Duchenne muscular dystrophy.
Connolly AM, Malkus EC, Mendell JR, Flanigan KM, Miller JP, Schierbecker JR, Siener CA, Golumbek PT, Zaidman CM, Mcdonald CM, Johnson L, Nicorici A, Karachunski PI, Day JW, Kelecic JM, Lowes LP, Alfano LN, Darras BT, Kang PB, Quigley J, Pasternak AE, Florence JM, MDA DMD Clinical Research Network
Muscle Nerve. 2015 Apr; 51(4)522-32. doi: 10.1002/mus.24346.

PMID:
    25056178
    [PubMed - indexed for MEDLINE]
Related citations


Clinicopathological associations in temporal lobe epilepsy patients utilising the current ILAE focal cortical dysplasia classification.
Johnson AM, Sugo E, Barreto D, Cunningham AM, Hiew CC, Lawson JA, Somerville ER, Connolly AM, Bye AM
Epilepsy Res. 2014 Oct; 108(8)1345-51. doi: 10.1016/j.eplepsyres.2014.06.013.

PMID:
    25048307
    [PubMed - indexed for MEDLINE]
Related citations


Ataluren treatment of patients with nonsense mutation dystrophinopathy.
Bushby K, Finkel R, Wong B, Barohn R, Campbell C, Comi GP, Connolly AM, Day JW, Flanigan KM, Goemans N, Jones KJ, Mercuri E, Quinlivan R, Renfroe JB, Russman B, Ryan MM, Tulinius M, Voit T, Moore SA, Lee Sweeney H, Abresch RT, Coleman KL, Eagle M, Florence J, Gappmaier E, Glanzman AM, Henricson E, Barth J, Elfring GL, Reha A, Spiegel RJ, O'donnell MW, Peltz SW, Mcdonald CM, PTC124-GD-007-DMD STUDY GROUP
Muscle Nerve. 2014 Oct; 50(4)477-87. doi: 10.1002/mus.24332.

PMID:
    25042182
    [PubMed - indexed for MEDLINE]
Related citations


Caring for children and adolescents with epilepsy: creating an innovative electronic educational resource.
Connolly AM, Slade R, Uppal P, Bye AM
J Clin Neurosci. 2014 Oct; 21(10)1831-2. doi: 10.1016/j.jocn.2014.02.019.

PMID:
    24906210
    [PubMed - indexed for MEDLINE]
Related citations


One year outcome of boys with Duchenne muscular dystrophy using the Bayley-III scales of infant and toddler development.
Connolly AM, Florence JM, Cradock MM, Eagle M, Flanigan KM, McDonald CM, Karachunski PI, Darras BT, Bushby K, Malkus EC, Golumbek PT, Zaidman CM, Miller JP, Mendell JR, MDA DMD Clinical Research Network
Pediatr Neurol. 2014 Jun; 50(6)557-63. doi: 10.1016/j.pediatrneurol.2014.02.006.

PMID:
    24842254
    [PubMed - indexed for MEDLINE]
Related citations


Novel mutations widen the phenotypic spectrum of slow skeletal/β-cardiac myosin (MYH7) distal myopathy.
Lamont PJ, Wallefeld W, Hilton-Jones D, Udd B, Argov Z, Barboi AC, Bonneman C, Boycott KM, Bushby K, Connolly AM, Davies N, Beggs AH, Cox GF, Dastgir J, DeChene ET, Gooding R, Jungbluth H, Muelas N, Palmio J, Penttilä S, Schmedding E, Suominen T, Straub V, Staples C, Van den Bergh PY, Vilchez JJ, Wagner KR, Wheeler PG, Wraige E, Laing NG
Hum Mutat. 2014 Jul; 35(7)868-79. doi: 10.1002/humu.22553.

PMID:
    24664454
    [PubMed - indexed for MEDLINE]
Related citations


Diagnostic approach to the congenital muscular dystrophies.
Bönnemann CG, Wang CH, Quijano-Roy S, Deconinck N, Bertini E, Ferreiro A, Muntoni F, Sewry C, Béroud C, Mathews KD, Moore SA, Bellini J, Rutkowski A, North KN, Members of International Standard of Care Committee for Congenital Muscular Dystrophies
Neuromuscul Disord. 2014 Apr; 24(4)289-311. doi: 10.1016/j.nmd.2013.12.011.

PMID:
    24581957
    [PubMed - indexed for MEDLINE]
Related citations


Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function.
Bibee KP, Cheng YJ, Ching JK, Marsh JN, Li AJ, Keeling RM, Connolly AM, Golumbek PT, Myerson JW, Hu G, Chen J, Shannon WD, Lanza GM, Weihl CC, Wickline SA
FASEB J. 2014 May; 28(5)2047-61. doi: 10.1096/fj.13-237388.

PMID:
    24500923
    [PubMed - indexed for MEDLINE]
Related citations