Patient Portal

Anne H. Cross, MD

Manny and Rosalyn Rosenthal - Dr. John Trotter MS Center Chair in Neuroimmunology
Professor, Neurology
Division of Adult Neurology
Section Head, Neuroimmunology

Specialty Areas

Multiple Sclerosis
Neurology - Adult
Transverse Myelitis
Optic Neuritis
Neuromyelitis optica

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Multiple sclerosis, neuromyelitis optica, transverse myelitis, CADASIL, CNS vasculitis, experimental autoimmune encephalomyelitis, autoimmune demyelination, lymphocyte-endothelial cell adhesions.

  • Location(s)
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures

Location(s)

Location(s)

Barnes-Jewish Hospital
McMillan Building

517 S. Euclid Avenue
St. Louis, MO 63110

Suite:
Floor:
Office Phone: 314-362-3293
Fax: 314-747-1345

Education

Education

Fellowship: Neuropathology, National Multiple Sclerosis Society, Albert Einstein College of Medicine, Bronx, New York 1990
Fellowship: Department of Virology/Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 1987
Fellowship: Neuroimmunology Branch, National Institutes of Health, Bethesda, Maryland 1986
Residency: Neurology, George Washington University, Washington, District of Columbia 1984
Medical Degree: University Of Alabama School of Medicine, Birmingham, Alabama 1980
B.S.: Chemistry, University of South Alabama, Mobile, Alabama 1976

Publication & Research

Publication & Research

Diffusion basis spectrum imaging for identifying pathologies in MS subtypes.
Shirani A, Sun P, Trinkaus K, Perantie DC, George A, Naismith RT, Schmidt RE, Song SK, Cross AH
Ann Clin Transl Neurol. 2019 Oct 6; doi: 10.1002/acn3.50903.

PMID:
    31588688
    [PubMed - as supplied by publisher]
Related citations


An overview of the current state of evidence for the role of specific diets in multiple sclerosis.
Evans E, Levasseur V, Cross AH, Piccio L
Mult Scler Relat Disord. 2019 Sep 9; 36101393. doi: 10.1016/j.msard.2019.101393.

PMID:
    31574403
    [PubMed - as supplied by publisher]
Related citations


T cells producing GM-CSF and IL-13 are enriched in the cerebrospinal fluid of relapsing MS patients.
Ghezzi L, Cantoni C, Cignarella F, Bollman B, Cross AH, Salter A, Galimberti D, Cella M, Piccio L
Mult Scler. 2019 Jun 25; 1352458519852092. doi: 10.1177/1352458519852092.

PMID:
    31237799
    [PubMed - as supplied by publisher]
Related citations


A Novel Gradient Echo Plural Contrast Imaging Method Detects Brain Tissue Abnormalities in Patients With TBI Without Evident Anatomical Changes on Clinical MRI: A Pilot Study.
Astafiev SV, Wen J, Brody DL, Cross AH, Anokhin AP, Zinn KL, Corbetta M, Yablonskiy DA
Mil Med. 2019 Mar 1; 184(Suppl 1)218-227. doi: 10.1093/milmed/usy394.

PMID:
    30901451
    [PubMed - indexed for MEDLINE]
Related citations


The association between handedness and clinicodemographic characteristics in people with multiple sclerosis: a brief report.
Shirani A, Cross AH, Naismith RT, Multiple Sclerosis Partners Advancing Technology and Health Solutions Investigators#.
Mult Scler J Exp Transl Clin. 2019 Jan-Mar; 5(1)2055217319832031. doi: 10.1177/2055217319832031.

PMID:
    30834138
    [PubMed]
Related citations


Misdiagnosis of multiple sclerosis: Impact of the 2017 McDonald criteria on clinical practice.
Solomon AJ, Naismith RT, Cross AH
Neurology. 2019 Jan 1; 92(1)26-33. doi: 10.1212/WNL.0000000000006583.

PMID:
    30381369
    [PubMed - indexed for MEDLINE]
Related citations


Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis.
Xiang B, Wen J, Cross AH, Yablonskiy DA
J Magn Reson Imaging. 2019 Feb; 49(2)487-498. doi: 10.1002/jmri.26218.

PMID:
    30155934
    [PubMed - in process]
Related citations


Histopathological correlation of diffusion basis spectrum imaging metrics of a biopsy-proven inflammatory demyelinating brain lesion: A brief report.
Shirani A, Sun P, Schmidt RE, Trinkaus K, Naismith RT, Song SK, Cross AH
Mult Scler. 2018 Jul 1; 1352458518786072. doi: 10.1177/1352458518786072.

PMID:
    29992856
    [PubMed - as supplied by publisher]
Related citations


A case of oligodendroglioma and multiple sclerosis: Occam's razor or Hickam's dictum?
Shirani A, Wu GF, Giannini C, Cross AH
BMJ Case Rep. 2018 Jun 28; 2018pii: bcr-2018-225318. doi: 10.1136/bcr-2018-225318.

PMID:
    29954769
    [PubMed - indexed for MEDLINE]
Related citations


Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota.
Cignarella F, Cantoni C, Ghezzi L, Salter A, Dorsett Y, Chen L, Phillips D, Weinstock GM, Fontana L, Cross AH, Zhou Y, Piccio L
Cell Metab. 2018 Jun 5; 27(6)1222-1235.e6. doi: 10.1016/j.cmet.2018.05.006.

PMID:
    29874567
    [PubMed - indexed for MEDLINE]
Related citations


Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Evans E, Piccio L, Cross AH
JAMA Neurol. 2018 Aug 1; 75(8)1013-1021. doi: 10.1001/jamaneurol.2018.0611.

PMID:
    29710293
    [PubMed - indexed for MEDLINE]
Related citations


Effectiveness of alternative dose fingolimod for multiple sclerosis.
Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I
Neurol Clin Pract. 2018 Apr; 8(2)102-107. doi: 10.1212/CPJ.0000000000000434.

PMID:
    29708225
    [PubMed]
Related citations


Disease-Modifying Treatment in Progressive Multiple Sclerosis.
Ciotti JR, Cross AH
Curr Treat Options Neurol. 2018 Apr 7; 20(5)12. doi: 10.1007/s11940-018-0496-3.

PMID:
    29627873
    [PubMed]
Related citations


Refining the use of MRI to predict multiple sclerosis.
Cross AH, Naismith RT
Lancet Neurol. 2018 Feb; 17(2)105-106. doi: 10.1016/S1474-4422(17)30459-3.

PMID:
    29275978
    [PubMed - indexed for MEDLINE]
Related citations


Intensity ratio to improve black hole assessment in multiple sclerosis.
Adusumilli G, Trinkaus K, Sun P, Lancia S, Viox JD, Wen J, Naismith RT, Cross AH
Mult Scler Relat Disord. 2018 Jan; 19140-147. doi: 10.1016/j.msard.2017.11.020.

PMID:
    29223871
    [PubMed - indexed for MEDLINE]
Related citations


Limbic system damage in MS: MRI assessment and correlations with clinical testing.
Wen J, Yablonskiy DA, Salter A, Cross AH
PLoS One. 2017; 12(11)e0187915. doi: 10.1371/journal.pone.0187915.

PMID:
    29121642
    [PubMed - indexed for MEDLINE]
Related citations


High risk of postpartum relapses in neuromyelitis optica spectrum disorder.
Klawiter EC, Bove R, Elsone L, Alvarez E, Borisow N, Cortez M, Mateen F, Mealy MA, Sorum J, Mutch K, Tobyne SM, Ruprecht K, Buckle G, Levy M, Wingerchuk D, Paul F, Cross AH, Jacobs A, Chitnis T, Weinshenker B
Neurology. 2017 Nov 28; 89(22)2238-2244. doi: 10.1212/WNL.0000000000004681.

PMID:
    29093070
    [PubMed - indexed for MEDLINE]
Related citations


Streamlined EDSS for use in multiple sclerosis clinical practice: Development and cross-sectional comparison to EDSS.
Baldassari LE, Salter AR, Longbrake EE, Cross AH, Naismith RT
Mult Scler. 2018 Sep; 24(10)1347-1355. doi: 10.1177/1352458517721357.

PMID:
    28766993
    [PubMed - indexed for MEDLINE]
Related citations


Dimethyl fumarate induces changes in B- and T-lymphocyte function independent of the effects on absolute lymphocyte count.
Longbrake EE, Cantoni C, Chahin S, Cignarella F, Cross AH, Piccio L
Mult Scler. 2018 May; 24(6)728-738. doi: 10.1177/1352458517707069.

PMID:
    28480794
    [PubMed - indexed for MEDLINE]
Related citations


Speaking out about gender imbalance in invited speakers improves diversity.
Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, Harris TH, Cross AH
Nat Immunol. 2017 Apr 18; 18(5)475-478. doi: 10.1038/ni.3707.

PMID:
    28418385
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Anne Cross, MD

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2018:

Company Name: Genentech, Inc.

Royalties:

Equity: No

Consulting/Advisory Board: $10,000 - $19,999

Speaker Fees:

Reporting Date: May 01, 2019