Patient Portal

Anne H. Cross, MD

Manny and Rosalyn Rosenthal - Dr. John Trotter MS Center Chair in Neuroimmunology
Professor, Neurology
Division of Adult Neurology
Section Head, Neuroimmunology

Specialty Areas

Multiple Sclerosis
Neurology - Adult
Transverse Myelitis
Optic Neuritis
Neuromyelitis optica

Board Certifications

Neurology

Hospital Affiliations

Barnes-Jewish Hospital

Referral Information

Physician Referral Required

Areas of Clinical Interest

Multiple sclerosis, neuromyelitis optica, transverse myelitis, CADASIL, CNS vasculitis, experimental autoimmune encephalomyelitis, autoimmune demyelination, lymphocyte-endothelial cell adhesions.

  • Maps & Directions
  • Education
  • Publication & Research
  • In the News
  • Financial Disclosures

Maps & Directions

Maps & Directions

Barnes-Jewish Hospital
McMillan Building

517 S. Euclid Avenue
St. Louis, MO 63110

Suite:
Floor:
Office Phone: 314-362-3293
Fax: 314-747-1345

Education

Education

Fellowship: Neuropathology, National Multiple Sclerosis Society, Albert Einstein College of Medicine, Bronx, New York 1990
Fellowship: Department of Virology/Molecular Biology, St. Jude Children's Research Hospital, Memphis, TN 1987
Fellowship: Neuroimmunology Branch, National Institutes of Health, Bethesda, Maryland 1986
Residency: Neurology, George Washington University, Washington, District of Columbia 1984
Medical Degree: University Of Alabama School of Medicine, Birmingham, Alabama 1980
B.S.: Chemistry, University of South Alabama, Mobile, Alabama 1976

Publication & Research

Publication & Research

Misdiagnosis of multiple sclerosis: Impact of the 2017 McDonald criteria on clinical practice.
Solomon AJ, Naismith RT, Cross AH
Neurology. 2018 Oct 31; pii: 10.1212/WNL.0000000000006583. doi: 10.1212/WNL.0000000000006583.

PMID:
    30381369
    [PubMed - as supplied by publisher]
Related citations


Single scan quantitative gradient recalled echo MRI for evaluation of tissue damage in lesions and normal appearing gray and white matter in multiple sclerosis.
Xiang B, Wen J, Cross AH, Yablonskiy DA
J Magn Reson Imaging. 2018 Aug 29; doi: 10.1002/jmri.26218.

PMID:
    30155934
    [PubMed - as supplied by publisher]
Related citations


Histopathological correlation of diffusion basis spectrum imaging metrics of a biopsy-proven inflammatory demyelinating brain lesion: A brief report.
Shirani A, Sun P, Schmidt RE, Trinkaus K, Naismith RT, Song SK, Cross AH
Mult Scler. 2018 Jul 1; 1352458518786072. doi: 10.1177/1352458518786072.

PMID:
    29992856
    [PubMed - as supplied by publisher]
Related citations


A case of oligodendroglioma and multiple sclerosis: Occam's razor or Hickam's dictum?
Shirani A, Wu GF, Giannini C, Cross AH
BMJ Case Rep. 2018 Jun 28; 2018pii: bcr-2018-225318. doi: 10.1136/bcr-2018-225318.

PMID:
    29954769
    [PubMed - indexed for MEDLINE]
Related citations


Intermittent Fasting Confers Protection in CNS Autoimmunity by Altering the Gut Microbiota.
Cignarella F, Cantoni C, Ghezzi L, Salter A, Dorsett Y, Chen L, Phillips D, Weinstock GM, Fontana L, Cross AH, Zhou Y, Piccio L
Cell Metab. 2018 Jun 5; 27(6)1222-1235.e6. doi: 10.1016/j.cmet.2018.05.006.

PMID:
    29874567
    [PubMed - in process]
Related citations


Use of Vitamins and Dietary Supplements by Patients With Multiple Sclerosis: A Review.
Evans E, Piccio L, Cross AH
JAMA Neurol. 2018 Aug 1; 75(8)1013-1021. doi: 10.1001/jamaneurol.2018.0611.

PMID:
    29710293
    [PubMed - in process]
Related citations


Effectiveness of alternative dose fingolimod for multiple sclerosis.
Longbrake EE, Kantor D, Pawate S, Bradshaw MJ, von Geldern G, Chahin S, Cross AH, Parks BJ, Rice M, Khoury SJ, Yamout B, Zeineddine M, Russell-Giller S, Caminero-Rodriguez A, Edwards K, Lathi E, VanderKodde D, Meador W, Berkovich R, Ge L, Bacon TE, Kister I
Neurol Clin Pract. 2018 Apr; 8(2)102-107. doi: 10.1212/CPJ.0000000000000434.

PMID:
    29708225
    [PubMed]
Related citations


Disease-Modifying Treatment in Progressive Multiple Sclerosis.
Ciotti JR, Cross AH
Curr Treat Options Neurol. 2018 Apr 7; 20(5)12. doi: 10.1007/s11940-018-0496-3.

PMID:
    29627873
    [PubMed]
Related citations


Refining the use of MRI to predict multiple sclerosis.
Cross AH, Naismith RT
Lancet Neurol. 2018 Feb; 17(2)105-106. doi: 10.1016/S1474-4422(17)30459-3.

PMID:
    29275978
    [PubMed - in process]
Related citations


Intensity ratio to improve black hole assessment in multiple sclerosis.
Adusumilli G, Trinkaus K, Sun P, Lancia S, Viox JD, Wen J, Naismith RT, Cross AH
Mult Scler Relat Disord. 2018 Jan; 19140-147. doi: 10.1016/j.msard.2017.11.020.

PMID:
    29223871
    [PubMed - indexed for MEDLINE]
Related citations


Limbic system damage in MS: MRI assessment and correlations with clinical testing.
Wen J, Yablonskiy DA, Salter A, Cross AH
PLoS One. 2017; 12(11)e0187915. doi: 10.1371/journal.pone.0187915.

PMID:
    29121642
    [PubMed - indexed for MEDLINE]
Related citations


High risk of postpartum relapses in neuromyelitis optica spectrum disorder.
Klawiter EC, Bove R, Elsone L, Alvarez E, Borisow N, Cortez M, Mateen F, Mealy MA, Sorum J, Mutch K, Tobyne SM, Ruprecht K, Buckle G, Levy M, Wingerchuk D, Paul F, Cross AH, Jacobs A, Chitnis T, Weinshenker B
Neurology. 2017 Nov 28; 89(22)2238-2244. doi: 10.1212/WNL.0000000000004681.

PMID:
    29093070
    [PubMed - indexed for MEDLINE]
Related citations


Streamlined EDSS for use in multiple sclerosis clinical practice: Development and cross-sectional comparison to EDSS.
Baldassari LE, Salter AR, Longbrake EE, Cross AH, Naismith RT
Mult Scler. 2018 Sep; 24(10)1347-1355. doi: 10.1177/1352458517721357.

PMID:
    28766993
    [PubMed - in process]
Related citations


Dimethyl fumarate induces changes in B- and T-lymphocyte function independent of the effects on absolute lymphocyte count.
Longbrake EE, Cantoni C, Chahin S, Cignarella F, Cross AH, Piccio L
Mult Scler. 2018 May; 24(6)728-738. doi: 10.1177/1352458517707069.

PMID:
    28480794
    [PubMed - in process]
Related citations


Speaking out about gender imbalance in invited speakers improves diversity.
Klein RS, Voskuhl R, Segal BM, Dittel BN, Lane TE, Bethea JR, Carson MJ, Colton C, Rosi S, Anderson A, Piccio L, Goverman JM, Benveniste EN, Brown MA, Tiwari-Woodruff SK, Harris TH, Cross AH
Nat Immunol. 2017 Apr 18; 18(5)475-478. doi: 10.1038/ni.3707.

PMID:
    28418385
    [PubMed - indexed for MEDLINE]
Related citations


Diffusion MRI quantifies early axonal loss in the presence of nerve swelling.
Lin TH, Chiang CW, Perez-Torres CJ, Sun P, Wallendorf M, Schmidt RE, Cross AH, Song SK
J Neuroinflammation. 2017 Apr 7; 14(1)78. doi: 10.1186/s12974-017-0852-3.

PMID:
    28388913
    [PubMed - indexed for MEDLINE]
Related citations


Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study.
Bove R, Elsone L, Alvarez E, Borisow N, Cortez MM, Mateen FJ, Mealy MA, Mutch K, Tobyne S, Ruprecht K, Buckle G, Levy M, Wingerchuk DM, Paul F, Cross AH, Weinshenker B, Jacob A, Klawiter EC, Chitnis T
Neurol Neuroimmunol Neuroinflamm. 2017 May; 4(3)e339. doi: 10.1212/NXI.0000000000000339.

PMID:
    28382320
    [PubMed]
Related citations


Amelioration of EAE by a cryptic epitope of myelin oligodendrocyte glycoprotein.
Lyons JA, Riter MM, Almatrook AM, Ramsbottom MJ, Cross AH
J Neuroimmunol. 2016 Nov 15; 30066-73. doi: 10.1016/j.jneuroim.2016.06.006.

PMID:
    27423965
    [PubMed - indexed for MEDLINE]
Related citations


"A new imaging modality to non-invasively assess multiple sclerosis pathology".
Cross AH, Song SK
J Neuroimmunol. 2017 Mar 15; 30481-85. doi: 10.1016/j.jneuroim.2016.10.002.

PMID:
    27773433
    [PubMed - indexed for MEDLINE]
Related citations


The contemporary spectrum of multiple sclerosis misdiagnosis: A multicenter study.
Solomon AJ, Bourdette DN, Cross AH, Applebee A, Skidd PM, Howard DB, Spain RI, Cameron MH, Kim E, Mass MK, Yadav V, Whitham RH, Longbrake EE, Naismith RT, Wu GF, Parks BJ, Wingerchuk DM, Rabin BL, Toledano M, Tobin WO, Kantarci OH, Carter JL, Keegan BM, Weinshenker BG
Neurology. 2016 Sep 27; 87(13)1393-9. doi: 10.1212/WNL.0000000000003152.

PMID:
    27581217
    [PubMed - indexed for MEDLINE]
Related citations

In the News

In the News

Anne Cross, MD

Financial Disclosures

Financial Disclosures

Disclosure of Financial Interests with Industry

Washington University and its physicians and health professionals are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians and health professionals work collaboratively with pharmaceutical, medical device or other medical care related companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our physicians and health professionals have an ownership or potential ownership interest in a commercial company; and/or are paid by a commercial company to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians or health professionals must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this website, physicians and health professionals earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

This physician reported the following financial interests during calendar year 2017:

Company Name: Biogen IDEC

Royalties:

Equity: No

Consulting/Advisory Board: $10,000 - $19,999

Speaker Fees:

Reporting Date: May 01, 2018