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Andrew L. Kau, MD

Instructor, Medicine
Division of Allergy/Immunology

Specialty Areas

Allergy/Immunology
Asthma

Board Certifications

Internal Medicine
Allergy and Immunology

Hospital Affiliations

Barnes-Jewish West County Hospital
Barnes-Jewish Hospital

Areas of Clinical Interest

Immunodeficiency, asthma, urticaria

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Barnes-Jewish West County Hospital
Medical Building One

1040 N. Mason Road
Creve Coeur, MO 63141

Suite: 205
Office Phone: (314) 996-8670

Education

Education

Bachelor of Science, Chemistry: Emory University, Atlanta, GA 1998
Medical Degree: Washington University School of Medicine, St. Louis, MO 2006
PhD, Biochemistry: Washington University School of Medicine, St. Louis, MO 2006
Fellowship, Allergy and Immunology: Washington University School of Medicine, St. Louis, MO 2011
Fellowship, Research - Molecular Microbiology: Washington University School of Medicine, St. Louis, MO 2005
Fullbright Research Fellow, Institute for Organic Chemistry and Biochemistry: University of Bonn, Bonn, Germany 1999
Fellowship, Clinical Research: Washington University School of Medicine, St. Louis, MO 2013
Residency, Internal Medicine: The Johns Hopkins Hospital, Baltimore, MD 2008

Publication & Research

Publication & Research

<i>Helicobacter</i> species are potent drivers of colonic T cell responses in homeostasis and inflammation.
Chai JN, Peng Y, Rengarajan S, Solomon BD, Ai TL, Shen Z, Perry JSA, Knoop KA, Tanoue T, Narushima S, Honda K, Elson CO, Newberry RD, Stappenbeck TS, Kau AL, Peterson DA, Fox JG, Hsieh CS
Sci Immunol. 2017 Jul 21; 2(13)pii: eaal5068. doi: 10.1126/sciimmunol.aal5068.

PMID:
    28733471
    [PubMed]
Related citations


Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist.
Spaulding CN, Klein RD, Ruer S, Kau AL, Schreiber HL, Cusumano ZT, Dodson KW, Pinkner JS, Fremont DH, Janetka JW, Remaut H, Gordon JI, Hultgren SJ
Nature. 2017 Jun 22; 546(7659)528-532. doi: 10.1038/nature22972.

PMID:
    28614296
    [PubMed - indexed for MEDLINE]
Related citations


Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice.
Planer JD, Peng Y, Kau AL, Blanton LV, Ndao IM, Tarr PI, Warner BB, Gordon JI
Nature. 2016 Jun 9; 534(7606)263-6. doi: 10.1038/nature17940.

PMID:
    27279225
    [PubMed - indexed for MEDLINE]
Related citations


Immune dysregulation underlies a subset of patients with chronic idiopathic pruritus.
Xu AZ, Tripathi SV, Kau AL, Schaffer A, Kim BS
J Am Acad Dermatol. 2016 May; 74(5)1017-20. doi: 10.1016/j.jaad.2015.11.029.

PMID:
    27085236
    [PubMed - indexed for MEDLINE]
Related citations


Functional characterization of IgA-targeted bacterial taxa from undernourished Malawian children that produce diet-dependent enteropathy.
Kau AL, Planer JD, Liu J, Rao S, Yatsunenko T, Trehan I, Manary MJ, Liu TC, Stappenbeck TS, Maleta KM, Ashorn P, Dewey KG, Houpt ER, Hsieh CS, Gordon JI
Sci Transl Med. 2015 Feb 25; 7(276)276ra24. doi: 10.1126/scitranslmed.aaa4877.

PMID:
    25717097
    [PubMed - indexed for MEDLINE]
Related citations


Distinct contributions of Aire and antigen-presenting-cell subsets to the generation of self-tolerance in the thymus.
Perry JSA, Lio CJ, Kau AL, Nutsch K, Yang Z, Gordon JI, Murphy KM, Hsieh CS
Immunity. 2014 Sep 18; 41(3)414-426. doi: 10.1016/j.immuni.2014.08.007.

PMID:
    25220213
    [PubMed - indexed for MEDLINE]
Related citations


Anti-interleukin 4 and 13 for asthma treatment in the era of endotypes.
Kau AL, Korenblat PE
Curr Opin Allergy Clin Immunol. 2014 Dec; 14(6)570-5. doi: 10.1097/ACI.0000000000000108.

PMID:
    25159182
    [PubMed - indexed for MEDLINE]
Related citations


Anti-interleukin 4 and 13 for asthma treatment in the era of endotypes.
Kau AL, Korenblat PE
Curr Opin Allergy Clin Immunol. 2014 Aug 19;

PMID:
    25144263
    [PubMed - as supplied by publisher]
Related citations


Gut microbiota from twins discordant for obesity modulate metabolism in mice.
Ridaura VK, Faith JJ, Rey FE, Cheng J, Duncan AE, Kau AL, Griffin NW, Lombard V, Henrissat B, Bain JR, Muehlbauer MJ, Ilkayeva O, Semenkovich CF, Funai K, Hayashi DK, Lyle BJ, Martini MC, Ursell LK, Clemente JC, Van Treuren W, Walters WA, Knight R, Newgard CB, Heath AC, Gordon JI
Science. 2013 Sep 6; 341(6150)1241214. doi: 10.1126/science.1241214.

PMID:
    24009397
    [PubMed - indexed for MEDLINE]
Related citations


Pilin and sortase residues critical for endocarditis- and biofilm-associated pilus biogenesis in Enterococcus faecalis.
Nielsen HV, Flores-Mireles AL, Kau AL, Kline KA, Pinkner JS, Neiers F, Normark S, Henriques-Normark B, Caparon MG, Hultgren SJ
J Bacteriol. 2013 Oct; 195(19)4484-95. doi: 10.1128/JB.00451-13.

PMID:
    23913319
    [PubMed - indexed for MEDLINE]
Related citations


Gut microbiomes of Malawian twin pairs discordant for kwashiorkor.
Smith MI, Yatsunenko T, Manary MJ, Trehan I, Mkakosya R, Cheng J, Kau AL, Rich SS, Concannon P, Mychaleckyj JC, Liu J, Houpt E, Li JV, Holmes E, Nicholson J, Knights D, Ursell LK, Knight R, Gordon JI
Science. 2013 Feb 1; 339(6119)548-54. doi: 10.1126/science.1229000.

PMID:
    23363771
    [PubMed - indexed for MEDLINE]
Related citations


Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Henao-Mejia J, Elinav E, Jin C, Hao L, Mehal WZ, Strowig T, Thaiss CA, Kau AL, Eisenbarth SC, Jurczak MJ, Camporez JP, Shulman GI, Gordon JI, Hoffman HM, Flavell RA
Nature. 2012 Feb 1; 482(7384)179-85. doi: 10.1038/nature10809.

PMID:
    22297845
    [PubMed - indexed for MEDLINE]
Related citations


Human nutrition, the gut microbiome and the immune system.
Kau AL, Ahern PP, Griffin NW, Goodman AL, Gordon JI
Nature. 2011 Jun 15; 474(7351)327-36. doi: 10.1038/nature10213.

PMID:
    21677749
    [PubMed - indexed for MEDLINE]
Related citations


NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.
Elinav E, Strowig T, Kau AL, Henao-Mejia J, Thaiss CA, Booth CJ, Peaper DR, Bertin J, Eisenbarth SC, Gordon JI, Flavell RA
Cell. 2011 May 27; 145(5)745-57. doi: 10.1016/j.cell.2011.04.022.

PMID:
    21565393
    [PubMed - indexed for MEDLINE]
Related citations


Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications.
Yilmaz P, Kottmann R, Field D, Knight R, Cole JR, Amaral-Zettler L, Gilbert JA, Karsch-Mizrachi I, Johnston A, Cochrane G, Vaughan R, Hunter C, Park J, Morrison N, Rocca-Serra P, Sterk P, Arumugam M, Bailey M, Baumgartner L, Birren BW, Blaser MJ, Bonazzi V, Booth T, Bork P, Bushman FD, Buttigieg PL, Chain PS, Charlson E, Costello EK, Huot-Creasy H, Dawyndt P, DeSantis T, Fierer N, Fuhrman JA, Gallery RE, Gevers D, Gibbs RA, San Gil I, Gonzalez A, Gordon JI, Guralnick R, Hankeln W, Highlander S, Hugenholtz P, Jansson J, Kau AL, Kelley ST, Kennedy J, Knights D, Koren O, Kuczynski J, Kyrpides N, Larsen R, Lauber CL, Legg T, Ley RE, Lozupone CA, Ludwig W, Lyons D, Maguire E, Methé BA, Meyer F, Muegge B, Nakielny S, Nelson KE, Nemergut D, Neufeld JD, Newbold LK, Oliver AE, Pace NR, Palanisamy G, Peplies J, Petrosino J, Proctor L, Pruesse E, Quast C, Raes J, Ratnasingham S, Ravel J, Relman DA, Assunta-Sansone S, Schloss PD, Schriml L, Sinha R, Smith MI, Sodergren E, Spo A, Stombaugh J, Tiedje JM, Ward DV, Weinstock GM, Wendel D, White O, Whiteley A, Wilke A, Wortman JR, Yatsunenko T, Glöckner FO
Nat Biotechnol. 2011 May; 29(5)415-20. doi: 10.1038/nbt.1823.

PMID:
    21552244
    [PubMed - indexed for MEDLINE]
Related citations


Contribution of autolysin and Sortase a during Enterococcus faecalis DNA-dependent biofilm development.
Guiton PS, Hung CS, Kline KA, Roth R, Kau AL, Hayes E, Heuser J, Dodson KW, Caparon MG, Hultgren SJ
Infect Immun. 2009 Sep; 77(9)3626-38. doi: 10.1128/IAI.00219-09.

PMID:
    19528211
    [PubMed - indexed for MEDLINE]
Related citations


Mechanism for sortase localization and the role of sortase localization in efficient pilus assembly in Enterococcus faecalis.
Kline KA, Kau AL, Chen SL, Lim A, Pinkner JS, Rosch J, Nallapareddy SR, Murray BE, Henriques-Normark B, Beatty W, Caparon MG, Hultgren SJ
J Bacteriol. 2009 May; 191(10)3237-47. doi: 10.1128/JB.01837-08.

PMID:
    19286802
    [PubMed - indexed for MEDLINE]
Related citations


Enterococcus faecalis tropism for the kidneys in the urinary tract of C57BL/6J mice.
Kau AL, Martin SM, Lyon W, Hayes E, Caparon MG, Hultgren SJ
Infect Immun. 2005 Apr; 73(4)2461-8.

PMID:
    15784592
    [PubMed - indexed for MEDLINE]
Related citations


Interaction of uropathogenic Escherichia coli with host uroepithelium.
Kau AL, Hunstad DA, Hultgren SJ
Curr Opin Microbiol. 2005 Feb; 8(1)54-9.

PMID:
    15694857
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Human microbiota, mucosal immunity