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Amy E. Riek, MD

Assistant Professor, Medicine 
Endocrinology, Metabolism & Lipid Research

Specialty Areas

Diabetes
Lipid Disease

Board Certifications

Internal Medicine
Endocrinology, Diabetes, and Metabolism

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

General endocrinology, thyroid disease, vitamin D metabolism, diabetes

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Medicine Multispecialty Center

4921 Parkview Place
St. Louis, MO 63110

Suite: C
Floor: 5
Office Phone: 314-362-3500
Fax: 314-747-2460

Education

Education

MS -Clinical Investigation: Washington University School of Medicine, St. Louis, MO 2012
Fellowship, Endocrinology, Diabetes & Metabolism: Washington University School of Medicine, St. Louis, MO 2011
Residency - Internal Medicine: Barnes-Jewish Hospital, St. Louis, MO 2008
Medical Degree: Washington University School of Medicine, St. Louis, MO 2005
BS, Biochemistry and Molecular Biology: University of Wisconsin, Madison, WI 2001

Publication & Research

Publication & Research

Deletion of JNK2 prevents vitamin-D-deficiency-induced hypertension and atherosclerosis in mice.
Oh J, Riek AE, Zhang RM, Williams SAS, Darwech I, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2017 Sep 23; pii: S0960-0760(17)30262-5. doi: 10.1016/j.jsbmb.2017.09.014.

PMID:
    28951226
    [PubMed - as supplied by publisher]
Related citations


Vitamin D<sub>3</sub> supplementation decreases a unique circulating monocyte cholesterol pool in patients with type 2 diabetes.
Riek AE, Oh J, Darwech I, Worthy V, Lin X, Ostlund RE Jr, Zhang RM, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2017 Sep 21; pii: S0960-0760(17)30259-5. doi: 10.1016/j.jsbmb.2017.09.011.

PMID:
    28941998
    [PubMed - as supplied by publisher]
Related citations


Adiposity and Cardiometabolic Risk in Children With and Without Antipsychotic Drug Treatment.
Nicol GE, de Las Fuentes L, Riek AE, Bernal-Mizrachi C, Lenze EJ, Miller JP, Schweiger JA, Yingling MD, Huang VJ, Dixon DJ, Hennekens CH, Newcomer JW
J Clin Endocrinol Metab. 2015 Sep; 100(9)3418-26. doi: 10.1210/jc.2015-2119.

PMID:
    26186300
    [PubMed - indexed for MEDLINE]
Related citations


Deletion of macrophage Vitamin D receptor promotes insulin resistance and monocyte cholesterol transport to accelerate atherosclerosis in mice.
Oh J, Riek AE, Darwech I, Funai K, Shao J, Chin K, Sierra OL, Carmeliet G, Ostlund RE Jr, Bernal-Mizrachi C
Cell Rep. 2015 Mar 24; 10(11)1872-86.

PMID:
    25801026
    [PubMed - indexed for MEDLINE]
Related citations


25(OH) vitamin D suppresses macrophage adhesion and migration by downregulation of ER stress and scavenger receptor A1 in type 2 diabetes.
Riek AE, Oh J, Darwech I, Moynihan CE, Bruchas RR, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2014 Oct; 144 Pt A172-9. doi: 10.1016/j.jsbmb.2013.10.016.

PMID:
    24184871
    [PubMed - indexed for MEDLINE]
Related citations


The St. Louis African American health-heart study: methodology for the study of cardiovascular disease and depression in young-old African Americans.
Bruchas RR, de Las Fuentes L, Carney RM, Reagan JL, Bernal-Mizrachi C, Riek AE, Gu CC, Bierhals A, Schootman M, Malmstrom TK, Burroughs TE, Stein PK, Miller DK, Dávila-Román VG
BMC Cardiovasc Disord. 2013 Sep 8; 1366. doi: 10.1186/1471-2261-13-66.

PMID:
    24011389
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D deficiency induces high blood pressure and accelerates atherosclerosis in mice.
Weng S, Sprague JE, Oh J, Riek AE, Chin K, Garcia M, Bernal-Mizrachi C
PLoS One. 2013; 8(1)e54625. doi: 10.1371/journal.pone.0054625.

PMID:
    23349943
    [PubMed - indexed for MEDLINE]
Related citations


1,25(OH)2 vitamin D suppresses macrophage migration and reverses atherogenic cholesterol metabolism in type 2 diabetic patients.
Riek AE, Oh J, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2013 Jul; 136309-12. doi: 10.1016/j.jsbmb.2012.12.019.

PMID:
    23333932
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D suppression of endoplasmic reticulum stress promotes an antiatherogenic monocyte/macrophage phenotype in type 2 diabetic patients.
Riek AE, Oh J, Sprague JE, Timpson A, de las Fuentes L, Bernal-Mizrachi L, Schechtman KB, Bernal-Mizrachi C
J Biol Chem. 2012 Nov 9; 287(46)38482-94. doi: 10.1074/jbc.M112.386912.

PMID:
    23012375
    [PubMed - indexed for MEDLINE]
Related citations


Endoplasmic reticulum stress controls M2 macrophage differentiation and foam cell formation.
Oh J, Riek AE, Weng S, Petty M, Kim D, Colonna M, Cella M, Bernal-Mizrachi C
J Biol Chem. 2012 Apr 6; 287(15)11629-41. doi: 10.1074/jbc.M111.338673.

PMID:
    22356914
    [PubMed - indexed for MEDLINE]
Related citations


The pharmacological management of osteoporosis.
Riek AE, Towler DA
Mo Med. 2011 Mar-Apr; 108(2)118-23.

PMID:
    21568234
    [PubMed - indexed for MEDLINE]
Related citations


Vitamin D regulates macrophage cholesterol metabolism in diabetes.
Riek AE, Oh J, Bernal-Mizrachi C
J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2)430-3. doi: 10.1016/j.jsbmb.2010.03.018.

PMID:
    20338238
    [PubMed - indexed for MEDLINE]
Related citations


Implications of vitamin D deficiency in pregnancy and lactation.
Mulligan ML, Felton SK, Riek AE, Bernal-Mizrachi C
Am J Obstet Gynecol. 2010 May; 202(5)429.e1-9. doi: 10.1016/j.ajog.2009.09.002.

PMID:
    19846050
    [PubMed - indexed for MEDLINE]
Related citations


Inpatient glycemic control on the vascular surgery service.
Theilen BM, Gritzke KA, Knutsen PG, Riek AE, McGill JB, Sicard GA, Tobin GS
Endocr Pract. 2008 Mar; 14(2)185-91.

PMID:
    18308656
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Vitamin D, cardiovascular disease, type 2 diabetes