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Faculty Physicians

Amjad Horani, MD

Instructor, Pediatrics
Division of Pediatric Allergy, Immunology and Pulmonary Medicine

Specialty Areas

Pediatric Allergy
Pediatric Immunology
Pediatric Pulmonary Disease

Hospital Affiliations

St. Louis Children's Hospital

Languages

Arabic
Hebrew
Basic French

Areas of Clinical Interest

Primary Ciliary Dyskinesia, Cystic Fibrosis, Asthma

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Education

Education

B.Sc., with distinction, Medical Sciences: Hebrew University of Jerusalem, Israel 1999
Pediatric Residency: Hadassah-Hebrew University Medical Center, Jerusalem, Israel 2009
Advanced Fellowship: Pediatric Allery, Immunology, & Pulmonary Medicine, St. Louis Children's Hospital 2014
Medical Degree: Hebrew Univesity of Jerusalem, Jerusalem, Israel 2004

Publication & Research

Publication & Research

Primary ciliary dyskinesia and associated sensory ciliopathies.
Horani A, Ferkol TW
Expert Rev Respir Med. 2016 May; 10(5)569-76. doi: 10.1586/17476348.2016.1165612.

PMID:
    26967669
    [PubMed - in process]
Related citations


Genetics and biology of primary ciliary dyskinesia.
Horani A, Ferkol TW, Dutcher SK, Brody SL
Paediatr Respir Rev. 2016 Mar; 1818-24. doi: 10.1016/j.prrv.2015.09.001.

PMID:
    26476603
    [PubMed - in process]
Related citations


Response to Snijders et al.
Horani A, Brody SL, Ferkol TW
Pediatr Res. 2014 Sep; 76(3)322. doi: 10.1038/pr.2014.80.

PMID:
    24933009
    [PubMed - indexed for MEDLINE]
Related citations


Picking up speed: advances in the genetics of primary ciliary dyskinesia.
Horani A, Brody SL, Ferkol TW
Pediatr Res. 2014 Jan; 75(1-2)158-64. doi: 10.1038/pr.2013.200.

PMID:
    24192704
    [PubMed - indexed for MEDLINE]
Related citations


CCDC65 mutation causes primary ciliary dyskinesia with normal ultrastructure and hyperkinetic cilia.
Horani A, Brody SL, Ferkol TW, Shoseyov D, Wasserman MG, Ta-shma A, Wilson KS, Bayly PV, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Elpeleg O, Kerem E
PLoS One. 2013; 8(8)e72299. doi: 10.1371/journal.pone.0072299.

PMID:
    23991085
    [PubMed - indexed for MEDLINE]
Related citations


Applications of mouse airway epithelial cell culture for asthma research.
Horani A, Dickinson JD, Brody SL
Methods Mol Biol. 2013; 103291-107. doi: 10.1007/978-1-62703-496-8_7.

PMID:
    23943446
    [PubMed - indexed for MEDLINE]
Related citations


NKp46 regulates allergic responses.
Ghadially H, Horani A, Glasner A, Elboim M, Gazit R, Shoseyov D, Mandelboim O
Eur J Immunol. 2013 Nov; 43(11)3006-16. doi: 10.1002/eji.201343388.

PMID:
    23878025
    [PubMed - indexed for MEDLINE]
Related citations


Rho-associated protein kinase inhibition enhances airway epithelial Basal-cell proliferation and lentivirus transduction.
Horani A, Nath A, Wasserman MG, Huang T, Brody SL
Am J Respir Cell Mol Biol. 2013 Sep; 49(3)341-7. doi: 10.1165/rcmb.2013-0046TE.

PMID:
    23713995
    [PubMed - indexed for MEDLINE]
Related citations


LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects.
Horani A, Ferkol TW, Shoseyov D, Wasserman MG, Oren YS, Kerem B, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Brody SL, Elpeleg O, Kerem E
PLoS One. 2013; 8(3)e59436. doi: 10.1371/journal.pone.0059436.

PMID:
    23527195
    [PubMed - indexed for MEDLINE]
Related citations


Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia.
Horani A, Druley TE, Zariwala MA, Patel AC, Levinson BT, Van Arendonk LG, Thornton KC, Giacalone JC, Albee AJ, Wilson KS, Turner EH, Nickerson DA, Shendure J, Bayly PV, Leigh MW, Knowles MR, Brody SL, Dutcher SK, Ferkol TW
Am J Hum Genet. 2012 Oct 5; 91(4)685-93. doi: 10.1016/j.ajhg.2012.08.022.

PMID:
    23040496
    [PubMed - indexed for MEDLINE]
Related citations


Triphala (PADMA) extract alleviates bronchial hyperreactivity in a mouse model through liver and spleen immune modulation and increased anti-oxidative effects.
Horani A, Shoseyov D, Ginsburg I, Mruwat R, Doron S, Amer J, Safadi R
Ther Adv Respir Dis. 2012 Aug; 6(4)199-210. doi: 10.1177/1753465812452194.

PMID:
    22763675
    [PubMed - indexed for MEDLINE]
Related citations


Sensory functions of motile cilia and implication for bronchiectasis.
Jain R, Javidan-Nejad C, Alexander-Brett J, Horani A, Cabellon MC, Walter MJ, Brody SL
Front Biosci (Schol Ed). 2012 Jan 1; 41088-98.

PMID:
    22202111
    [PubMed - indexed for MEDLINE]
Related citations


Immune modulation of ovalbumin-induced lung injury in mice using β-glucosylceramide and a potential role of the liver.
Horani A, Shoseyov D, Doron S, Mruwat R, Amer J, Kerem E, Safadi R
Immunobiology. 2011 May; 216(5)548-57. doi: 10.1016/j.imbio.2010.10.002.

PMID:
    21074892
    [PubMed - indexed for MEDLINE]
Related citations


Amelioration of hepatic fibrosis via Padma Hepaten is associated with altered natural killer T lymphocytes.
Ginsburg I, Koren E, Horani A, Mahamid M, Doron S, Muhanna N, Amer J, Safadi R
Clin Exp Immunol. 2009 Jul; 157(1)155-64. doi: 10.1111/j.1365-2249.2009.03936.x.

PMID:
    19659781
    [PubMed - indexed for MEDLINE]
Related citations


Activation of hepatic stellate cells after phagocytosis of lymphocytes: A novel pathway of fibrogenesis.
Muhanna N, Doron S, Wald O, Horani A, Eid A, Pappo O, Friedman SL, Safadi R
Hepatology. 2008 Sep; 48(3)963-77. doi: 10.1002/hep.22413.

PMID:
    18726940
    [PubMed - indexed for MEDLINE]
Related citations


Immunomodulatory effects of plasminogen activators on hepatic fibrogenesis.
Higazi AA, El-Haj M, Melhem A, Horani A, Pappo O, Alvarez CE, Muhanna N, Friedman SL, Safadi R
Clin Exp Immunol. 2008 Apr; 152(1)163-73. doi: 10.1111/j.1365-2249.2008.03606.x.

PMID:
    18279442
    [PubMed - indexed for MEDLINE]
Related citations


Clinical characteristics of eyes demonstrating atypical patterns in scanning laser polarimetry.
Orlev A, Horani A, Rapson Y, Cohen MJ, Blumenthal EZ
Eye (Lond). 2008 Nov; 22(11)1378-83.

PMID:
    17627289
    [PubMed - indexed for MEDLINE]
Related citations


Lymphocyte-hepatic stellate cell proximity suggests a direct interaction.
Muhanna N, Horani A, Doron S, Safadi R
Clin Exp Immunol. 2007 May; 148(2)338-47.

PMID:
    17437422
    [PubMed - indexed for MEDLINE]
Related citations


Estimating intraocular pressure using a glass rod.
Frenkel S, Katz S, Horani A, Kaiserman I, Asleh SA, Blumenthal EZ
Ann Ophthalmol (Skokie). 2006 Fall; 38(3)195-9.

PMID:
    17416953
    [PubMed - indexed for MEDLINE]
Related citations


Test-retest variability in visual field testing using frequency doubling technology.
Horani A, Frenkel S, Blumenthal EZ
Eur J Ophthalmol. 2007 Mar-Apr; 17(2)203-7.

PMID:
    17415693
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Dr. Horani's main research interest focuses on airway epithelial cell pathogensis including primary ciliary dyskinesia (PCD).