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Amanda Fishback Cashen, MD

Associate Professor, Medicine
Division of Oncology
Section of Bone Marrow Transplant

Specialty Areas

Bone Marrow Transplant
Hematologic Malignancies
Leukemia
Lymphoma
Oncology

Board Certifications

Internal Medicine
Medical Oncology

Hospital Affiliations

Barnes-Jewish Hospital

Areas of Clinical Interest

Oncology, bone marrow transplant, hematology, cancer, lymphoma, leukemia

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Siteman Cancer Center - South County

5225 MidAmerica Plaza
St. Louis, MO 63129

Office Phone: 314-454-8304

Center for Advanced Medicine

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 7
Office Phone: 314-454-8304
Fax: 314-454-7551

Education

Education

Fellowship: Hematology/Oncology, Washington University School of Medicine, St. Louis, Missouri 2006
Chief Resident: John Cochran VA Medical Center, Washington University School of Medicine, St. Louis, Missouri 2002
Residency: Barnes-Jewish Hospital, Washington University School of Medicine, St. Louis, Missouri 2002
Medical Degree: Washington University School of Medicine, St. Louis, Missouri 1999
B.S.: Yale University, New Haven, Connecticut 1995

Publication & Research

Publication & Research

First-in-human phase 1 clinical study of the IL-15 superagonist complex ALT-803 to treat relapse after transplantation.
Romee R, Cooley S, Berrien-Elliott MM, Westervelt P, Verneris MR, Wagner JE, Weisdorf DJ, Blazar BR, Ustun C, DeFor TE, Vivek S, Peck L, DiPersio JF, Cashen AF, Kyllo R, Musiek A, Schaffer A, Anadkat MJ, Rosman I, Miller D, Egan JO, Jeng EK, Rock A, Wong HC, Fehniger TA, Miller JS
Blood. 2018 Jun 7; 131(23)2515-2527. doi: 10.1182/blood-2017-12-823757.

PMID:
    29463563
    [PubMed - in process]
Related citations


Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.
Wong TN, Miller CA, Jotte MRM, Bagegni N, Baty JD, Schmidt AP, Cashen AF, Duncavage EJ, Helton NM, Fiala M, Fulton RS, Heath SE, Janke M, Luber K, Westervelt P, Vij R, DiPersio JF, Welch JS, Graubert TA, Walter MJ, Ley TJ, Link DC
Nat Commun. 2018 Jan 31; 9(1)455. doi: 10.1038/s41467-018-02858-0.

PMID:
    29386642
    [PubMed - indexed for MEDLINE]
Related citations


Patterns of infectious complications in acute myeloid leukemia and myelodysplastic syndromes patients treated with 10-day decitabine regimen.
Ali AM, Weisel D, Gao F, Uy GL, Cashen AF, Jacoby MA, Wartman LD, Ghobadi A, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Schroeder MA, Westervelt P, DiPersio JF, Welch JS
Cancer Med. 2017 Dec; 6(12)2814-2821. doi: 10.1002/cam4.1231.

PMID:
    29058375
    [PubMed - indexed for MEDLINE]
Related citations


Lack of a Prognostic Impact of the MyD88 L265P Mutation for Diffuse Large B Cell Lymphoma Patients Undergoing Autologous Stem Cell Transplantation.
Lee YS, Liu J, Fricano KA, Webb EM, Toolsie DR, Jones S, Rhoads JA, Vij R, Cashen AF, Abboud CN, Westervelt P, Bartlett NL, Dipersio JF, Kreisel FH, Lim KH
Biol Blood Marrow Transplant. 2017 Dec; 23(12)2199-2204. doi: 10.1016/j.bbmt.2017.08.022.

PMID:
    28847710
    [PubMed - indexed for MEDLINE]
Related citations


Results of a Prospective Randomized, Open-Label, Noninferiority Study of Tbo-Filgrastim (Granix) versus Filgrastim (Neupogen) in Combination with Plerixafor for Autologous Stem Cell Mobilization in Patients with Multiple Myeloma and Non-Hodgkin Lymphoma.
Bhamidipati PK, Fiala MA, Grossman BJ, DiPersio JF, Stockerl-Goldstein K, Gao F, Uy GL, Westervelt P, Schroeder MA, Cashen AF, Abboud CN, Vij R
Biol Blood Marrow Transplant. 2017 Dec; 23(12)2065-2069. doi: 10.1016/j.bbmt.2017.07.023.

PMID:
    28797783
    [PubMed - indexed for MEDLINE]
Related citations


Minimal activity of nanoparticle albumin-bound (nab) paclitaxel in relapsed or refractory lymphomas: results of a phase-I study.
Goyal S, Oak E, Luo J, Cashen AF, Carson K, Fehniger T, DiPersio J, Bartlett NL, Wagner-Johnston ND
Leuk Lymphoma. 2018 Feb; 59(2)357-362. doi: 10.1080/10428194.2017.1330954.

PMID:
    28597723
    [PubMed - indexed for MEDLINE]
Related citations


Phase I/II Study of Intravenous Plerixafor Added to a Mobilization Regimen of Granulocyte Colony-Stimulating Factor in Lymphoma Patients Undergoing Autologous Stem Cell Collection.
Cashen AF, Rettig M, Gao F, Smith A, Abboud C, Stockerl-Goldstein K, Vij R, Uy G, Westervelt P, DiPersio J
Biol Blood Marrow Transplant. 2017 Aug; 23(8)1282-1289. doi: 10.1016/j.bbmt.2017.04.024.

PMID:
    28476490
    [PubMed - indexed for MEDLINE]
Related citations


Safety and tolerability of idelalisib, lenalidomide, and rituximab in relapsed and refractory lymphoma: the Alliance for Clinical Trials in Oncology A051201 and A051202 phase 1 trials.
Smith SM, Pitcher BN, Jung SH, Bartlett NL, Wagner-Johnston N, Park SI, Richards KL, Cashen AF, Jaslowski A, Smith SE, Cheson BD, Hsi E, Leonard JP
Lancet Haematol. 2017 Apr; 4(4)e176-e182. doi: 10.1016/S2352-3026(17)30028-5.

PMID:
    28314699
    [PubMed - indexed for MEDLINE]
Related citations


Mobilization of allogeneic peripheral blood stem cell donors with intravenous plerixafor mobilizes a unique graft.
Schroeder MA, Rettig MP, Lopez S, Christ S, Fiala M, Eades W, Mir FA, Shao J, McFarland K, Trinkaus K, Shannon W, Deych E, Yu J, Vij R, Stockerl-Goldstein K, Cashen AF, Uy GL, Abboud CN, Westervelt P, DiPersio JF
Blood. 2017 May 11; 129(19)2680-2692. doi: 10.1182/blood-2016-09-739722.

PMID:
    28292947
    [PubMed - indexed for MEDLINE]
Related citations


Mutational landscape and response are conserved in peripheral blood of AML and MDS patients during decitabine therapy.
Duncavage EJ, Uy GL, Petti AA, Miller CA, Lee YS, Tandon B, Gao F, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Jacoby MA, Cashen AF, Wartman LD, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ, Welch JS
Blood. 2017 Mar 9; 129(10)1397-1401. doi: 10.1182/blood-2016-10-745273.

PMID:
    28082444
    [PubMed - indexed for MEDLINE]
Related citations


Predictive factors and outcomes for ibrutinib therapy in relapsed/refractory mantle cell lymphoma-a "real world" study.
Epperla N, Hamadani M, Cashen AF, Ahn KW, Oak E, Kanate AS, Calzada O, Cohen JB, Farmer L, Ghosh N, Tallarico M, Nabhan C, Costa LJ, Kenkre VP, Hari PN, Fenske TS
Hematol Oncol. 2017 Dec; 35(4)528-535. doi: 10.1002/hon.2380.

PMID:
    28066928
    [PubMed - indexed for MEDLINE]
Related citations


Recurrent somatic mutations affecting B-cell receptor signaling pathway genes in follicular lymphoma.
Krysiak K, Gomez F, White BS, Matlock M, Miller CA, Trani L, Fronick CC, Fulton RS, Kreisel F, Cashen AF, Carson KR, Berrien-Elliott MM, Bartlett NL, Griffith M, Griffith OL, Fehniger TA
Blood. 2017 Jan 26; 129(4)473-483. doi: 10.1182/blood-2016-07-729954.

PMID:
    28064239
    [PubMed - indexed for MEDLINE]
Related citations


RB but not R-HCVAD is a feasible induction regimen prior to auto-HCT in frontline MCL: results of SWOG Study S1106.
Chen RW, Li H, Bernstein SH, Kahwash S, Rimsza LM, Forman SJ, Constine L, Shea TC, Cashen AF, Blum KA, Fenske TS, Barr PM, Phillips T, Leblanc M, Fisher RI, Cheson BD, Smith SM, Faham M, Wilkins J, Leonard JP, Kahl BS, Friedberg JW
Br J Haematol. 2017 Mar; 176(5)759-769. doi: 10.1111/bjh.14480.

PMID:
    27992063
    [PubMed - indexed for MEDLINE]
Related citations


TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Welch JS, Petti AA, Miller CA, Fronick CC, O'Laughlin M, Fulton RS, Wilson RK, Baty JD, Duncavage EJ, Tandon B, Lee YS, Wartman LD, Uy GL, Ghobadi A, Tomasson MH, Pusic I, Romee R, Fehniger TA, Stockerl-Goldstein KE, Vij R, Oh ST, Abboud CN, Cashen AF, Schroeder MA, Jacoby MA, Heath SE, Luber K, Janke MR, Hantel A, Khan N, Sukhanova MJ, Knoebel RW, Stock W, Graubert TA, Walter MJ, Westervelt P, Link DC, DiPersio JF, Ley TJ
N Engl J Med. 2016 Nov 24; 375(21)2023-2036. doi: 10.1056/NEJMoa1605949.

PMID:
    27959731
    [PubMed - indexed for MEDLINE]
Related citations


Dynamic changes in the clonal structure of MDS and AML in response to epigenetic therapy.
Uy GL, Duncavage EJ, Chang GS, Jacoby MA, Miller CA, Shao J, Heath S, Elliott K, Reineck T, Fulton RS, Fronick CC, O'Laughlin M, Ganel L, Abboud CN, Cashen AF, DiPersio JF, Wilson RK, Link DC, Welch JS, Ley TJ, Graubert TA, Westervelt P, Walter MJ
Leukemia. 2017 Apr; 31(4)872-881. doi: 10.1038/leu.2016.282.

PMID:
    27740633
    [PubMed - indexed for MEDLINE]
Related citations


Phase II Study of Propylene Glycol-Free Melphalan Combined with Carmustine, Etoposide, and Cytarabine for Myeloablative Conditioning in Lymphoma Patients Undergoing Autologous Stem Cell Transplantation.
Cashen AF, Fletcher T, Ceriotti C, Gao F, Ghobadi A, Vij R, Stockerl-Goldstein K, DiPersio J, Abboud C
Biol Blood Marrow Transplant. 2016 Dec; 22(12)2155-2158. doi: 10.1016/j.bbmt.2016.08.026.

PMID:
    27575541
    [PubMed - indexed for MEDLINE]
Related citations


Longitudinal Body Composition Changes in Diffuse Large B-cell Lymphoma Survivors: A Retrospective Cohort Study of United States Veterans.
Xiao DY, Luo S, O'Brian K, Sanfilippo KM, Ganti A, Riedell P, Lynch RC, Liu W, Kahl BS, Cashen AF, Fehniger TA, Carson KR
J Natl Cancer Inst. 2016 Nov; 108(11)doi: 10.1093/jnci/djw145.

PMID:
    27381623
    [PubMed - indexed for MEDLINE]
Related citations


Comparison of Outcomes after Peripheral Blood Haploidentical versus Matched Unrelated Donor Allogeneic Hematopoietic Cell Transplantation in Patients with Acute Myeloid Leukemia: A Retrospective Single-Center Review.
Rashidi A, DiPersio JF, Westervelt P, Vij R, Schroeder MA, Cashen AF, Fehniger TA, Romee R
Biol Blood Marrow Transplant. 2016 Sep; 22(9)1696-1701. doi: 10.1016/j.bbmt.2016.05.010.

PMID:
    27223108
    [PubMed - indexed for MEDLINE]
Related citations


Radioimmunotherapy-based conditioning for hematopoietic stem cell transplantation: Another step forward.
Ali AM, Dehdashti F, DiPersio JF, Cashen AF
Blood Rev. 2016 Sep; 30(5)389-99. doi: 10.1016/j.blre.2016.04.007.

PMID:
    27174151
    [PubMed - in process]
Related citations


HLA disparity is not inconsequential in peripheral blood T-replete haploidentical hematopoietic stem cell transplantation.
Rashidi A, DiPersio JF, Westervelt P, Abboud CN, Schroeder MA, Pusic I, Cashen AF, Fehniger TA, Romee R
Bone Marrow Transplant. 2016 Sep; 51(9)1275-8. doi: 10.1038/bmt.2016.117.

PMID:
    27159170
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

bone marrow transplant, lymphoma, leukemia