Patient Portal

Alexander C. Chen, MD

Associate Professor, Medicine
Division of Pulmonary and Critical Care Medicine
Associate Professor, Surgery
Division of Cardiothoracic Surgery
Director of Interventional Pulmonology

Specialty Areas

Lung Disease
Interventional Pulmonology
Lung Cancer
Thoracic Oncology

Board Certifications

Pulmonary Medicine
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Pulmonary complications of cancer with special interest in malignant airway obstructions and recurrent malignant pleural effusion, pleural disease, lung masses and mediastinal adenopathy, interventional pulmonary

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917
Fax: 314-747-2200

Barnes-Jewish West County Hospital
Medical Building One

1040 N. Mason Road
Creve Coeur, MO 63141

Office Phone: 314-454-8917
Fax: 314-222-6253

Education

Education

Chief Resident: Internal Medicine, Barnes-Jewish Hospital, St. Louis MO 2005
Fellowship: Interventional Pulmonary Medicine, Washington University School of Medicine, St. Louis MO 2009
Medical Degree: University of Missouri, Kansas City, Kansas City, MO 2001
Residency: Internal Medicine, Barnes-Jewish Hospital, St. Louis 2004
Fellowship: Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis MO 2008

Publication & Research

Publication & Research

Influence of propofol on the electroencephalogram default mode network in patients of advanced age.
Ke JD, Xu M, Wang PP, Wang M, Tian M, Chen ACN
J Int Med Res. 2018 Sep 23; 300060518788241. doi: 10.1177/0300060518788241.

PMID:
    30246583
    [PubMed - as supplied by publisher]
Related citations


A reduction in inflammatory macrophages may contribute to skin cancer chemoprevention by nicotinamide.
Minocha R, Martin AJ, Chen AC, Scolyer RA, Lyons JG, McKenzie CA, Madore J, Halliday GM, Damian DL
J Invest Dermatol. 2018 Sep 20; pii: S0022-202X(18)32584-3. doi: 10.1016/j.jid.2018.08.018.

PMID:
    30244097
    [PubMed - as supplied by publisher]
Related citations


Application of a fluorescent marker with quantitative bioburden methods to assess cleanliness.
Hung IC, Chang HY, Cheng A, Chen AC, Ting L, Chen MW, Lai YH, Sheng WH
Infect Control Hosp Epidemiol. 2018 Nov; 39(11)1296-1300. doi: 10.1017/ice.2018.222.

PMID:
    30221609
    [PubMed - in process]
Related citations


PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa.
Burr LD, Rogers GB, Chen AC, Taylor SL, Bowler SD, Keating RL, Martin ML, Hasnain SZ, McGuckin MA
PLoS One. 2018; 13(8)e0202296. doi: 10.1371/journal.pone.0202296.

PMID:
    30114278
    [PubMed - in process]
Related citations


Early and late fixation of ulnar styloid base fractures yields different outcomes.
Chen AC, Chiu CH, Weng CJ, Chang SS, Cheng CY
J Orthop Surg Res. 2018 Jul 31; 13(1)193. doi: 10.1186/s13018-018-0899-6.

PMID:
    30064441
    [PubMed - in process]
Related citations


GRK5 Is Associated with the Regulation of Methadone Dosage in Heroin Dependence.
Wang SC, Chung RH, Kuo HW, Liu TH, Fang CP, Liu SC, Liu CC, Tsou HH, Chen ACH, Liu YL
Int J Neuropsychopharmacol. 2018 Oct 1; 21(10)910-917. doi: 10.1093/ijnp/pyy066.

PMID:
    30060048
    [PubMed - in process]
Related citations


The Impact of M-Health on the Self-Management of Diabetes: A Preliminary Study.
Chang HY, Chang HL, Chen AC, Yen CH
Stud Health Technol Inform. 2018; 25239-44.

PMID:
    30040680
    [PubMed - in process]
Related citations


Anteromedial fractures of the ulnar coronoid process: correlation between surgical outcomes and radiographic findings.
Chen AC, Weng CJ, Chou YC, Cheng CY
BMC Musculoskelet Disord. 2018 Jul 23; 19(1)248. doi: 10.1186/s12891-018-2162-z.

PMID:
    30037338
    [PubMed - in process]
Related citations


Immune Checkpoint Blockade in Advanced Renal-Cell Carcinoma.
Motzer RJ, McHenry MB, Chen AC
N Engl J Med. 2018 Jul 5; 379(1)92-93. doi: 10.1056/NEJMc1805988.

PMID:
    29972749
    [PubMed - indexed for MEDLINE]
Related citations


Change in Activities of Daily Living in the Year Following a Stroke: A Latent Growth Curve Analysis.
Pai HC, Lai MY, Chen AC, Lin PS
Nurs Res. 2018 Jul/Aug; 67(4)286-293. doi: 10.1097/NNR.0000000000000280.

PMID:
    29953043
    [PubMed - in process]
Related citations


Oxidative and endoplasmic reticulum stress in respiratory disease.
Chen AC, Burr L, McGuckin MA
Clin Transl Immunology. 2018; 7(6)e1019. doi: 10.1002/cti2.1019.

PMID:
    29928501
    [PubMed]
Related citations


Children with allergic diseases have an increased subsequent risk of migraine upon reaching school age.
Wei CC, Lin CL, Shen TC, Chen AC
J Investig Med. 2018 Oct; 66(7)1064-1068. doi: 10.1136/jim-2018-000715.

PMID:
    29903897
    [PubMed - in process]
Related citations


Long-term outcomes of modular metal prosthesis replacement in patients with irreparable radial head fractures.
Chen AC, Chou YC, Weng CJ, Cheng CY
J Orthop Surg Res. 2018 Jun 1; 13(1)134. doi: 10.1186/s13018-018-0844-8.

PMID:
    29859102
    [PubMed - in process]
Related citations


Internet Well-Being in Adolescents: A Concept Analysis.
Jo S, Chen AC
Stud Health Technol Inform. 2018; 25033.

PMID:
    29857364
    [PubMed - in process]
Related citations


Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks.
Leland BA, Chen AC, Zhao AY, Wharton RC, King MC
Elife. 2018 Apr 26; 7pii: e33402. doi: 10.7554/eLife.33402.

PMID:
    29697047
    [PubMed - in process]
Related citations


Biomechanics of osteochondral impact with cushioning and graft Insertion: Cartilage damage is correlated with delivered energy.
Su AW, Chen Y, Dong Y, Wailes DH, Wong VW, Chen AC, Cai S, Bugbee WD, Sah RL
J Biomech. 2018 May 17; 73127-136. doi: 10.1016/j.jbiomech.2018.03.037.

PMID:
    29628132
    [PubMed - in process]
Related citations


Estimating active layer thickness and volumetric water content from ground penetrating radar measurements in Barrow, Alaska.
Jafarov EE, Parsekian AD, Schaefer K, Liu L, Chen AC, Panda SK, Zhang T
Geosci Data J. 2017 Nov; 4(2)72-79. doi: 10.1002/gdj3.49.

PMID:
    29610660
    [PubMed]
Related citations


Multiple inflammasomes may regulate the interleukin-1-driven inflammation in protracted bacterial bronchitis.
Chen AC, Tran HB, Xi Y, Yerkovich ST, Baines KJ, Pizzutto SJ, Carroll M, Robertson AAB, Cooper MA, Schroder K, Simpson JL, Gibson PG, Hodge G, Masters IB, Buntain HM, Petsky HL, Prime SJ, Chang AB, Hodge S, Upham JW
ERJ Open Res. 2018 Jan; 4(1)pii: 00130-2017. doi: 10.1183/23120541.00130-2017.

PMID:
    29594175
    [PubMed]
Related citations


Airway cells from protracted bacterial bronchitis and bronchiectasis share similar gene expression profiles.
Chen AC, Pena OM, Nel HJ, Yerkovich ST, Chang AB, Baines KJ, Gibson PG, Petsky HL, Pizzutto SJ, Hodge S, Masters IB, Buntain HL, Upham JW
Pediatr Pulmonol. 2018 May; 53(5)575-582. doi: 10.1002/ppul.23984.

PMID:
    29575797
    [PubMed - in process]
Related citations


Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma.
Motzer RJ, Tannir NM, McDermott DF, Arén Frontera O, Melichar B, Choueiri TK, Plimack ER, Barthélémy P, Porta C, George S, Powles T, Donskov F, Neiman V, Kollmannsberger CK, Salman P, Gurney H, Hawkins R, Ravaud A, Grimm MO, Bracarda S, Barrios CH, Tomita Y, Castellano D, Rini BI, Chen AC, Mekan S, McHenry MB, Wind-Rotolo M, Doan J, Sharma P, Hammers HJ, Escudier B, CheckMate 214 Investigators.
N Engl J Med. 2018 Apr 5; 378(14)1277-1290. doi: 10.1056/NEJMoa1712126.

PMID:
    29562145
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Advanced techniques in diagnosis cancers of the lung