Patient Portal

Alexander C. Chen, MD

Associate Professor, Medicine
Division of Pulmonary and Critical Care Medicine
Associate Professor, Surgery
Division of Cardiothoracic Surgery
Director of Interventional Pulmonology

Specialty Areas

Lung Disease
Interventional Pulmonology
Lung Cancer
Thoracic Oncology

Board Certifications

Pulmonary Medicine
Internal Medicine
Critical Care Medicine

Hospital Affiliations

Barnes-Jewish Hospital
St. Louis Children's Hospital

Areas of Clinical Interest

Pulmonary complications of cancer with special interest in malignant airway obstructions and recurrent malignant pleural effusion, pleural disease, lung masses and mediastinal adenopathy, interventional pulmonary

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Center for Advanced Medicine
Lung Center

4921 Parkview Place
St. Louis, MO 63110

Suite: B
Floor: 8
Office Phone: 314-454-8917
Fax: 314-747-2200

Barnes-Jewish West County Hospital
Medical Building One

1040 N. Mason Road
Creve Coeur, MO 63141

Office Phone: 314-454-8917
Fax: 314-222-6253

Education

Education

Chief Resident: Internal Medicine, Barnes-Jewish Hospital, St. Louis MO 2005
Fellowship: Interventional Pulmonary Medicine, Washington University School of Medicine, St. Louis MO 2009
Medical Degree: University of Missouri, Kansas City, Kansas City, MO 2001
Residency: Internal Medicine, Barnes-Jewish Hospital, St. Louis 2004
Fellowship: Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis MO 2008

Publication & Research

Publication & Research

A new avenue for treating neuronal diseases: ceftriaxone, an old antibiotic demonstrating behavioral neuronal effects.
Tai CH, Bellesi M, Chen AC, Lin CL, Li HH, Lin PJ, Liao WC, Hung CS, Schwarting RK, Ho YJ
Behav Brain Res. 2019 Feb 12; pii: S0166-4328(18)31605-X. doi: 10.1016/j.bbr.2019.02.020.

PMID:
    30768995
    [PubMed - as supplied by publisher]
Related citations


Multiple Respiratory Microbiota Profiles Are Associated With Lower Airway Inflammation in Children With Protracted Bacterial Bronchitis.
Marsh RL, Smith-Vaughan HC, Chen ACH, Marchant JM, Yerkovich ST, Gibson PG, Pizzutto SJ, Hodge S, Upham JW, Chang AB
Chest. 2019 Jan 17; pii: S0012-3692(19)30010-8. doi: 10.1016/j.chest.2019.01.002.

PMID:
    30660785
    [PubMed - as supplied by publisher]
Related citations


Shenmai-Yin decreased the clearance of nifedipine in rats: The involvement of time-dependent inhibition of nifedipine oxidation.
Wang HJ, Lu CK, Chen WC, Chen AC, Ueng YF
J Food Drug Anal. 2019 Jan; 27(1)284-294. doi: 10.1016/j.jfda.2018.10.005.

PMID:
    30648582
    [PubMed - in process]
Related citations


Connexin 43 is involved in early differentiation of human embryonic stem cells.
Peng Q, Yue C, Chen ACH, Lee KC, Fong SW, Yeung WSB, Lee YL
Differentiation. 2018 Dec 19; 10533-44. doi: 10.1016/j.diff.2018.12.003.

PMID:
    30599359
    [PubMed - as supplied by publisher]
Related citations


Self-Renewal and Differentiation of Adipose-Derived Stem Cells (ADSCs) Stimulated by Multi-Axial Tensile Strain in a Pneumatic Microdevice.
Chiu CH, Tong YW, Yeh WL, Lei KF, Chen AC
Micromachines (Basel). 2018 Nov 19; 9(11)pii: E607. doi: 10.3390/mi9110607.

PMID:
    30463251
    [PubMed]
Related citations


Intermediate screws or kyphoplasty: Which method of posterior short-segment fixation is better for treating single-level thoracolumbar burst fractures?
Zhang J, Liu H, Liu H, Chen AC, He F, Zhou F, Yang H, Liu T
Eur Spine J. 2018 Nov 17; doi: 10.1007/s00586-018-5822-7.

PMID:
    30448987
    [PubMed - as supplied by publisher]
Related citations


Investigation of Growth Factor and Tenocyte Proliferation Induced by Platelet Rich Plasma (PRP) in a 3-Chamber Co-Culture Device.
Chiu CH, Higashikawa R, Yeh WL, Lei KF, Chen AC
Micromachines (Basel). 2018 Sep 7; 9(9)pii: E446. doi: 10.3390/mi9090446.

PMID:
    30424379
    [PubMed]
Related citations


Biochemical and Skeletal Outcomes of Parathyroidectomy for Normocalcemic (Incipient) Primary Hyperparathyroidism.
Sho S, Kuo EJ, Chen AC, Li N, Yeh MW, Livhits MJ
Ann Surg Oncol. 2019 Feb; 26(2)539-546. doi: 10.1245/s10434-018-6998-0.

PMID:
    30406488
    [PubMed - in process]
Related citations


Healthy hearts in pediatric heart transplant patients with an exercise and diet intervention via live video conferencing-Design and rationale.
Chen AC, Rosenthal DN, Couch SC, Berry S, Stauffer KJ, Brabender J, McDonald N, Lee D, Barkoff L, Nourse SE, Kazmucha J, Wang CJ, Olson I, Selamet Tierney ES
Pediatr Transplant. 2019 Feb; 23(1)e13316. doi: 10.1111/petr.13316.

PMID:
    30393915
    [PubMed - in process]
Related citations


Influence of propofol on the electroencephalogram default mode network in patients of advanced age.
Ke JD, Xu M, Wang PP, Wang M, Tian M, Chen ACN
J Int Med Res. 2018 Nov; 46(11)4660-4668. doi: 10.1177/0300060518788241.

PMID:
    30246583
    [PubMed - indexed for MEDLINE]
Related citations


A Reduction in Inflammatory Macrophages May Contribute to Skin Cancer Chemoprevention by Nicotinamide.
Minocha R, Martin AJ, Chen AC, Scolyer RA, Lyons JG, McKenzie CA, Madore J, Halliday GM, Damian DL
J Invest Dermatol. 2019 Feb; 139(2)467-469. doi: 10.1016/j.jid.2018.08.018.

PMID:
    30244097
    [PubMed - in process]
Related citations


Application of a fluorescent marker with quantitative bioburden methods to assess cleanliness.
Hung IC, Chang HY, Cheng A, Chen AC, Ting L, Chen MW, Lai YH, Sheng WH
Infect Control Hosp Epidemiol. 2018 Nov; 39(11)1296-1300. doi: 10.1017/ice.2018.222.

PMID:
    30221609
    [PubMed - in process]
Related citations


PPARγ is reduced in the airways of non-CF bronchiectasis subjects and is inversely correlated with the presence of Pseudomonas aeruginosa.
Burr LD, Rogers GB, Chen AC, Taylor SL, Bowler SD, Keating RL, Martin ML, Hasnain SZ, McGuckin MA
PLoS One. 2018; 13(8)e0202296. doi: 10.1371/journal.pone.0202296.

PMID:
    30114278
    [PubMed - indexed for MEDLINE]
Related citations


Early and late fixation of ulnar styloid base fractures yields different outcomes.
Chen AC, Chiu CH, Weng CJ, Chang SS, Cheng CY
J Orthop Surg Res. 2018 Jul 31; 13(1)193. doi: 10.1186/s13018-018-0899-6.

PMID:
    30064441
    [PubMed - indexed for MEDLINE]
Related citations


GRK5 Is Associated with the Regulation of Methadone Dosage in Heroin Dependence.
Wang SC, Chung RH, Kuo HW, Liu TH, Fang CP, Liu SC, Liu CC, Tsou HH, Chen ACH, Liu YL
Int J Neuropsychopharmacol. 2018 Oct 1; 21(10)910-917. doi: 10.1093/ijnp/pyy066.

PMID:
    30060048
    [PubMed - in process]
Related citations


The Impact of M-Health on the Self-Management of Diabetes: A Preliminary Study.
Chang HY, Chang HL, Chen AC, Yen CH
Stud Health Technol Inform. 2018; 25239-44.

PMID:
    30040680
    [PubMed - indexed for MEDLINE]
Related citations


Anteromedial fractures of the ulnar coronoid process: correlation between surgical outcomes and radiographic findings.
Chen AC, Weng CJ, Chou YC, Cheng CY
BMC Musculoskelet Disord. 2018 Jul 23; 19(1)248. doi: 10.1186/s12891-018-2162-z.

PMID:
    30037338
    [PubMed - in process]
Related citations


Immune Checkpoint Blockade in Advanced Renal-Cell Carcinoma.
Motzer RJ, McHenry MB, Chen AC
N Engl J Med. 2018 Jul 5; 379(1)92-93. doi: 10.1056/NEJMc1805988.

PMID:
    29972749
    [PubMed - indexed for MEDLINE]
Related citations


Change in Activities of Daily Living in the Year Following a Stroke: A Latent Growth Curve Analysis.
Pai HC, Lai MY, Chen AC, Lin PS
Nurs Res. 2018 Jul/Aug; 67(4)286-293. doi: 10.1097/NNR.0000000000000280.

PMID:
    29953043
    [PubMed - in process]
Related citations


Oxidative and endoplasmic reticulum stress in respiratory disease.
Chen AC, Burr L, McGuckin MA
Clin Transl Immunology. 2018; 7(6)e1019. doi: 10.1002/cti2.1019.

PMID:
    29928501
    [PubMed]
Related citations

Areas of Research Interest

Advanced techniques in diagnosis cancers of the lung