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Alex S. Evers, MD

Henry E. Mallinckrodt Professor, Anesthesiology
Head, Department of Anesthesiology

Specialty Areas

Anesthesiology
Critical Care Medicine

Board Certifications

Internal Medicine
Anesthesiology

Hospital Affiliations

Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Referral Information

Not Accepting New Patients

  • Education
  • Publication & Research

Education

Education

Fellowship: Department of Pharmacology, Washington University School of Medicine, St. Louis, Missouri 1986
Fellowship: Surgical Intensive Care, Massachusetts General Hospital, Boston, Massachusetts 1983
Residency: Anesthesia, Massachusetts General Hospital, Boston, Massachusetts 1982
Residency: Internal Medicine, Michael Resse Hospital, Chicago, Illinois 1981
Medical Degree: New York University Medical Center, New York, New York 1978

Publication & Research

Publication & Research

Activation and modulation of recombinant glycine and GABA<sub>A</sub> receptors by 4-halogenated analogues of propofol.
Germann AL, Shin DJ, Manion BD, Edge CJ, Smith EH, Franks NP, Evers AS, Akk G
Br J Pharmacol. 2016 Jul 26; doi: 10.1111/bph.13566.

PMID:
    27459129
    [PubMed - as supplied by publisher]
Related citations


In Reply.
Avidan MS, Evers AS
Anesthesiology. 2016 Aug; 125(2)428-9. doi: 10.1097/ALN.0000000000001181.

PMID:
    27433761
    [PubMed - in process]
Related citations


The GAS trial.
Orser BA, Evers AS, Suresh S, Hertz S
Lancet. 2016 Apr 16; 387(10028)1613-4. doi: 10.1016/S0140-6736(16)30199-4.

PMID:
    27116066
    [PubMed - indexed for MEDLINE]
Related citations


Multiple Non-Equivalent Interfaces Mediate Direct Activation of GABAA Receptors by Propofol.
Eaton MM, Germann AL, Arora R, Cao LQ, Gao X, Shin DJ, Wu A, Chiara DC, Cohen JB, Steinbach JH, Evers AS, Akk G
Curr Neuropharmacol. 2016 Feb 2;

PMID:
    26830963
    [PubMed - as supplied by publisher]
Related citations


The Fallacy of Persistent Postoperative Cognitive Decline.
Avidan MS, Evers AS
Anesthesiology. 2016 Feb; 124(2)255-8. doi: 10.1097/ALN.0000000000000958.

PMID:
    26785428
    [PubMed - indexed for MEDLINE]
Related citations


Mutational Analysis of the Putative High-Affinity Propofol Binding Site in Human β3 Homomeric GABAA Receptors.
Eaton MM, Cao LQ, Chen Z, Franks NP, Evers AS, Akk G
Mol Pharmacol. 2015 Oct; 88(4)736-45. doi: 10.1124/mol.115.100347.

PMID:
    26206487
    [PubMed - indexed for MEDLINE]
Related citations


Anesthetic neurotoxicity--clinical implications of animal models.
Rappaport BA, Suresh S, Hertz S, Evers AS, Orser BA
N Engl J Med. 2015 Feb 26; 372(9)796-7. doi: 10.1056/NEJMp1414786.

PMID:
    25714157
    [PubMed - indexed for MEDLINE]
Related citations


The neurosteroid 5β-pregnan-3α-ol-20-one enhances actions of etomidate as a positive allosteric modulator of α1β2γ2L GABAA receptors.
Li P, Bracamontes JR, Manion BD, Mennerick S, Steinbach JH, Evers AS, Akk G
Br J Pharmacol. 2014 Dec; 171(23)5446-57. doi: 10.1111/bph.12861.

PMID:
    25117207
    [PubMed - indexed for MEDLINE]
Related citations


Surgical safety checklists in ontario, Canada.
Avidan MS, Evers AS
N Engl J Med. 2014 Jun 12; 370(24)2350-1. doi: 10.1056/NEJMc1404583#SA5.

PMID:
    24918390
    [PubMed - indexed for MEDLINE]
Related citations


11-trifluoromethyl-phenyldiazirinyl neurosteroid analogues: potent general anesthetics and photolabeling reagents for GABAA receptors.
Chen ZW, Wang C, Krishnan K, Manion BD, Hastings R, Bracamontes J, Taylor A, Eaton MM, Zorumski CF, Steinbach JH, Akk G, Mennerick S, Covey DF, Evers AS
Psychopharmacology (Berl). 2014 Sep; 231(17)3479-91. doi: 10.1007/s00213-014-3568-4.

PMID:
    24756762
    [PubMed - indexed for MEDLINE]
Related citations


Neurosteroid analogues. 18. Structure-activity studies of ent-steroid potentiators of γ-aminobutyric acid type A receptors and comparison of their activities with those of alphaxalone and allopregnanolone.
Qian M, Krishnan K, Kudova E, Li P, Manion BD, Taylor A, Elias G, Akk G, Evers AS, Zorumski CF, Mennerick S, Covey DF
J Med Chem. 2014 Jan 9; 57(1)171-90. doi: 10.1021/jm401577c.

PMID:
    24328079
    [PubMed - indexed for MEDLINE]
Related citations


Increased risk of intraoperative awareness in patients with a history of awareness.
Aranake A, Gradwohl S, Ben-Abdallah A, Lin N, Shanks A, Helsten DL, Glick DB, Jacobsohn E, Villafranca AJ, Evers AS, Avidan MS, Mashour GA
Anesthesiology. 2013 Dec; 119(6)1275-83. doi: 10.1097/ALN.0000000000000023.

PMID:
    24113645
    [PubMed - indexed for MEDLINE]
Related citations


A propofol binding site on mammalian GABAA receptors identified by photolabeling.
Yip GM, Chen ZW, Edge CJ, Smith EH, Dickinson R, Hohenester E, Townsend RR, Fuchs K, Sieghart W, Evers AS, Franks NP
Nat Chem Biol. 2013 Nov; 9(11)715-20. doi: 10.1038/nchembio.1340.

PMID:
    24056400
    [PubMed - indexed for MEDLINE]
Related citations


In reply.
Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA
Anesthesiology. 2013 Mar; 118(3)759-60. doi: 10.1097/ALN.0b013e3182838bb4.

PMID:
    23426219
    [PubMed - indexed for MEDLINE]
Related citations


Sexual dysfunction in women on adjuvant endocrine therapy after breast cancer.
Baumgart J, Nilsson K, Evers AS, Kallak TK, Poromaa IS
Menopause. 2013 Feb; 20(2)162-8. doi: 10.1097/gme.0b013e31826560da.

PMID:
    22990756
    [PubMed - indexed for MEDLINE]
Related citations


What are we looking for? The question of resident selection.
Fleisher LA, Evers AS, Wiener-Kronish J, Ulatowski JA
Anesthesiology. 2012 Aug; 117(2)230-1.

PMID:
    22705567
    [PubMed - indexed for MEDLINE]
Related citations


Neurosteroid analog photolabeling of a site in the third transmembrane domain of the β3 subunit of the GABA(A) receptor.
Chen ZW, Manion B, Townsend RR, Reichert DE, Covey DF, Steinbach JH, Sieghart W, Fuchs K, Evers AS
Mol Pharmacol. 2012 Sep; 82(3)408-19. doi: 10.1124/mol.112.078410.

PMID:
    22648971
    [PubMed - indexed for MEDLINE]
Related citations


A neurosteroid analogue photolabeling reagent labels the colchicine-binding site on tubulin: a mass spectrometric analysis.
Chen ZW, Chen LH, Akentieva N, Lichti CF, Darbandi R, Hastings R, Covey DF, Reichert DE, Townsend RR, Evers AS
Electrophoresis. 2012 Feb; 33(4)666-74. doi: 10.1002/elps.201100434.

PMID:
    22451060
    [PubMed - indexed for MEDLINE]
Related citations


Perspective: Hospital support for anesthesiology departments: aligning incentives and improving productivity.
Hill LL, Evers AS
Acad Med. 2012 Mar; 87(3)348-55. doi: 10.1097/ACM.0b013e318244c36e.

PMID:
    22373631
    [PubMed - indexed for MEDLINE]
Related citations


Deep amino acid sequencing of native brain GABAA receptors using high-resolution mass spectrometry.
Chen ZW, Fuchs K, Sieghart W, Townsend RR, Evers AS
Mol Cell Proteomics. 2012 Jan; 11(1)M111.011445.

PMID:
    22338125
    [PubMed - indexed for MEDLINE]
Related citations