Patient Portal

Akinobu Itoh, MD, PhD

Assistant Professor, Surgery
Division of Cardiothoracic Surgery

Specialty Areas

Cardiac Surgery
Heart Transplantation
Heart Failure / Transplant

Board Certifications

Japanese Board of Surgery
Japanese Board of Cardiovascular Surgery

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Japanese

Areas of Clinical Interest

Heart valve repair/replacement, aortic root surgery, coronary artery bypass (bilateral IMA and off pump surgery),heart transplantation, mechanical assist device (LVAD/ECMO) for heart failure, pre/post operative patient care

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: (314) 362-8008
Fax: (314) 747-4216

Education

Education

Medical Degree: Tohoku School of Medicine, Sendai, Japan 1992
PhD : Mitral valve physiology and pathology, Tohoku School of Medicine, Sendai, Japan 2010
Residency: General Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2000
Residency: Cardiovascular Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2002
Fellowship (Research): Carl and Leah McConnell Cardiovascula Surgical Research, Stanford University School of Medicine, Stanford, CA 2008
Fellowship: Cardiovascular Surgery, St. Michael's Hospital, Toronto, Ontario 2011
Fellowship: Transplant / Heart Failure, St Michael's Hospital, Toronto, Ontario 2012

Publication & Research

Publication & Research

The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ
Nat Med. 2018 Jun 11; doi: 10.1038/s41591-018-0059-x.

PMID:
    29892064
    [PubMed - as supplied by publisher]
Related citations


Health Care Resource Use and Cost Implications in the MOMENTUM 3 Long-Term Outcome Study: A Randomized Controlled Trial of a Magnetically Levitated Cardiac Pump in Advanced Heart Failure.
Mehra MR, Salerno C, Cleveland JC, Pinney S, Yuzefpolskaya M, Milano CA, Itoh A, Goldstein DJ, Uriel N, Gulati S, Pagani FD, John R, Adamson RM, Bogaev RC, Thohan V, Chuang J, Sood P, Goates S, Silvestry SC
Circulation. 2018 May 27; pii: CIRCULATIONAHA.118.035722. doi: 10.1161/CIRCULATIONAHA.118.035722.

PMID:
    29807933
    [PubMed - as supplied by publisher]
Related citations


Outcomes and Predictors of Early Infection after Heart Transplantation.
Shultes KC, Shuster JE, Micek S, Vader JM, Balsara K, Itoh A, Tellor BR
Surg Infect (Larchmt). 2018 May 18; doi: 10.1089/sur.2017.295.

PMID:
    29775554
    [PubMed - as supplied by publisher]
Related citations


Evaluation of Clinical Outcomes with Phosphodiesterase-5 Inhibitor Therapy for Right Ventricular Dysfunction After Left Ventricular Assist Device Implantation.
Roberts KL, Shuster JE, Britt NS, Balsara KR, Graetz TJ, Helwani M, Itoh A, Tellor BR
ASAIO J. 2018 May 7; doi: 10.1097/MAT.0000000000000809.

PMID:
    29750687
    [PubMed - as supplied by publisher]
Related citations


Clinical Outcomes and Reduced Pulmonary Artery Pressure With Intra-Aortic Balloon Pump During Central Extracorporeal Life Support.
Tepper S, Garcia MB, Fischer I, Ahmed A, Khan A, Balsara KR, Masood MF, Itoh A
ASAIO J. 2018 Mar 30; doi: 10.1097/MAT.0000000000000788.

PMID:
    29613887
    [PubMed - as supplied by publisher]
Related citations


Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus.
Itoh A, Sadanari H, Takemoto M, Matsubara K, Daikoku T, Murayama T
Microbiol Immunol. 2018 May; 62(5)341-347. doi: 10.1111/1348-0421.12590.

PMID:
    29603339
    [PubMed - in process]
Related citations


Rituximab Induced Pulmonary Edema Managed with Extracorporeal Life Support.
Miller JR, Isakow W, Masood MF, Aguilar P, Sanfilippo KM, Balsara KR, Itoh A
Case Rep Crit Care. 2018; 20186039045. doi: 10.1155/2018/6039045.

PMID:
    29593914
    [PubMed]
Related citations


Are patterns of fine-scale spatial genetic structure consistent between sites within tropical tree species?
Smith JR, Ghazoul J, Burslem DFRP, Itoh A, Khoo E, Lee SL, Maycock CR, Nanami S, Ng KKS, Kettle CJ
PLoS One. 2018; 13(3)e0193501. doi: 10.1371/journal.pone.0193501.

PMID:
    29547644
    [PubMed - in process]
Related citations


Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure.
Mehra MR, Goldstein DJ, Uriel N, Cleveland JC Jr, Yuzefpolskaya M, Salerno C, Walsh MN, Milano CA, Patel CB, Ewald GA, Itoh A, Dean D, Krishnamoorthy A, Cotts WG, Tatooles AJ, Jorde UP, Bruckner BA, Estep JD, Jeevanandam V, Sayer G, Horstmanshof D, Long JW, Gulati S, Skipper ER, O'Connell JB, Heatley G, Sood P, Naka Y, MOMENTUM 3 Investigators.
N Engl J Med. 2018 Apr 12; 378(15)1386-1395. doi: 10.1056/NEJMoa1800866.

PMID:
    29526139
    [PubMed - indexed for MEDLINE]
Related citations


Internal driveline damage under the costal margin several years after HeartMate II implant: a series of three cases.
Ogawa M, Masood MF, Ewald GA, Vader JM, LaRue SJ, Cheng A, Balsara KR, Itoh A
J Artif Organs. 2018 Mar 3; doi: 10.1007/s10047-018-1029-2.

PMID:
    29502323
    [PubMed - as supplied by publisher]
Related citations


Diagnosis of LVAD Thrombus using a High-Avidity Fibrin-Specific <sup>99m</sup>Tc Probe.
Cui G, Akers WJ, Scott MJ, Nassif M, Allen JS, Schmieder AH, Paranandi KS, Itoh A, Beyder DD, Achilefu S, Ewald GA, Lanza GM
Theranostics. 2018; 8(4)1168-1179. doi: 10.7150/thno.20271.

PMID:
    29464007
    [PubMed - in process]
Related citations


Photoinduced Generation of Acyl Radicals from Simple Aldehydes, Access to 3-Acyl-4-arylcoumarin Derivatives, and Evaluation of Their Antiandrogenic Activities.
Kawaai K, Yamaguchi T, Yamaguchi E, Endo S, Tada N, Ikari A, Itoh A
J Org Chem. 2018 Feb 16; 83(4)1988-1996. doi: 10.1021/acs.joc.7b02933.

PMID:
    29327585
    [PubMed - indexed for MEDLINE]
Related citations


Aerobic Photooxidative Synthesis of β-Alkoxy Monohydroperoxides Using an Organo Photoredox Catalyst Controlled by a Base.
Asano Y, Nagasawa Y, Yamaguchi E, Itoh A
Chem Asian J. 2018 Feb 16; 13(4)409-412. doi: 10.1002/asia.201701742.

PMID:
    29327427
    [PubMed]
Related citations


Plant invasion: Another threat to the São Paulo Marsh Antwren (Formicivora paludicola), a species on the verge of extinction.
Del-Rio G, Rêgo MA, Silveira LF, Itoh A
PLoS One. 2017; 12(12)e0189465. doi: 10.1371/journal.pone.0189465.

PMID:
    29281668
    [PubMed - indexed for MEDLINE]
Related citations


Reply.
Tepper S, Itoh A
Ann Thorac Surg. 2018 Jun; 105(6)1861-1862. doi: 10.1016/j.athoracsur.2017.11.039.

PMID:
    29253464
    [PubMed - in process]
Related citations


Reply.
Tepper S, Itoh A
Ann Thorac Surg. 2018 Jun; 105(6)1858-1859. doi: 10.1016/j.athoracsur.2017.11.038.

PMID:
    29253462
    [PubMed - in process]
Related citations


The profound impact of combined severe acidosis and malperfusion on operative mortality in the surgical treatment of type A aortic dissection.
Lawton JS, Moon MR, Liu J, Koerner DJ, Kulshrestha K, Damiano RJ Jr, Maniar H, Itoh A, Balsara KR, Masood FM, Melby SJ, Pasque MK
J Thorac Cardiovasc Surg. 2018 Mar; 155(3)897-904. doi: 10.1016/j.jtcvs.2017.11.002.

PMID:
    29249502
    [PubMed - in process]
Related citations


Impact of age, sex, therapeutic intent, race and severity of advanced heart failure on short-term principal outcomes in the MOMENTUM 3 trial.
Goldstein DJ, Mehra MR, Naka Y, Salerno C, Uriel N, Dean D, Itoh A, Pagani FD, Skipper ER, Bhat G, Raval N, Bruckner BA, Estep JD, Cogswell R, Milano C, Fendelander L, O'Connell JB, Cleveland J, MOMENTUM 3 Investigators.
J Heart Lung Transplant. 2018 Jan; 37(1)7-14. doi: 10.1016/j.healun.2017.11.001.

PMID:
    29154131
    [PubMed - in process]
Related citations


Small leucine-rich repeat proteoglycans associated with mature insoluble elastin serve as binding sites for galectins.
Itoh A, Nonaka Y, Ogawa T, Nakamura T, Nishi N
Biosci Biotechnol Biochem. 2017 Nov; 81(11)2098-2104. doi: 10.1080/09168451.2017.1374828.

PMID:
    28958189
    [PubMed - indexed for MEDLINE]
Related citations


Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance.
Kuroki S, Okashita N, Baba S, Maeda R, Miyawaki S, Yano M, Yamaguchi M, Kitano S, Miyachi H, Itoh A, Yoshida M, Tachibana M
PLoS Genet. 2017 Sep; 13(9)e1007034. doi: 10.1371/journal.pgen.1007034.

PMID:
    28949961
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Clinical results in patients with LVAD, mitral valve dynamics after mitral valve repair, myocardial strain and structural alteration in heart disease