Patient Portal

Akinobu Itoh, MD, PhD

Assistant Professor, Surgery
Division of Cardiothoracic Surgery

Specialty Areas

Cardiac Surgery
Heart Transplantation
Heart Failure / Transplant

Board Certifications

Japanese Board of Surgery
Japanese Board of Cardiovascular Surgery

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Japanese

Areas of Clinical Interest

Heart valve repair/replacement, aortic root surgery, coronary artery bypass (bilateral IMA and off pump surgery),heart transplantation, mechanical assist device (LVAD/ECMO) for heart failure, pre/post operative patient care

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: (314) 362-8008
Fax: (314) 747-4216

Education

Education

Medical Degree: Tohoku School of Medicine, Sendai, Japan 1992
PhD : Mitral valve physiology and pathology, Tohoku School of Medicine, Sendai, Japan 2010
Residency: General Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2000
Residency: Cardiovascular Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2002
Fellowship (Research): Carl and Leah McConnell Cardiovascula Surgical Research, Stanford University School of Medicine, Stanford, CA 2008
Fellowship: Cardiovascular Surgery, St. Michael's Hospital, Toronto, Ontario 2011
Fellowship: Transplant / Heart Failure, St Michael's Hospital, Toronto, Ontario 2012

Publication & Research

Publication & Research

Subregional heterogeneity of somatosensory dysfunction in the insula.
Matsuda K, Satoh M, Tabei KI, Ueda Y, Itoh A, Ishikawa H, Matsuo K, Shindo A, Asahi M, Niwa A, Matsuura K, Tomimoto H
J Neurol Neurosurg Psychiatry. 2018 Nov 19; pii: jnnp-2018-319174. doi: 10.1136/jnnp-2018-319174.

PMID:
    30455405
    [PubMed - as supplied by publisher]
Related citations


Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells.
Itoh A, Nonaka Y, Ogawa T, Nakamura T, Nishi N
Glycobiology. 2018 Oct 24; doi: 10.1093/glycob/cwy099.

PMID:
    30383222
    [PubMed - as supplied by publisher]
Related citations


Heterologous production of free dihomo-γ-linolenic acid by Aspergillus oryzae and its extracellular release via surfactant supplementation.
Tamano K, Cox RS 3rd, Tsuge K, Miura A, Itoh A, Ishii J, Tamura T, Kondo A, Machida M
J Biosci Bioeng. 2018 Oct 13; pii: S1389-1723(18)30637-6. doi: 10.1016/j.jbiosc.2018.09.013.

PMID:
    30327168
    [PubMed - as supplied by publisher]
Related citations


Induction of Human-Lung-Cancer-A549-Cell Apoptosis by 4-Hydroperoxy-2-decenoic Acid Ethyl Ester through Intracellular ROS Accumulation and the Induction of Proapoptotic CHOP Expression.
Kamiya T, Watanabe M, Hara H, Mitsugi Y, Yamaguchi E, Itoh A, Adachi T
J Agric Food Chem. 2018 Oct 17; 66(41)10741-10747. doi: 10.1021/acs.jafc.8b04424.

PMID:
    30296076
    [PubMed - in process]
Related citations


Olefin Bifunctionalization: A Visible-light Photoredox-catalyzed Aryl Alkoxylation of Olefins.
Yamaguchi E, Tanaka W, Itoh A
Chem Asian J. 2018 Sep 24; doi: 10.1002/asia.201801211.

PMID:
    30251357
    [PubMed - as supplied by publisher]
Related citations


Effects of gem-dihydroperoxides against mutant copper‑zinc superoxide dismutase-mediated neurotoxicity.
Ueda T, Inden M, Asaka Y, Masaki Y, Kurita H, Tanaka W, Yamaguchi E, Itoh A, Hozumi I
Mol Cell Neurosci. 2018 Oct; 92177-184. doi: 10.1016/j.mcn.2018.09.001.

PMID:
    30193933
    [PubMed - in process]
Related citations


Visible-Light-Mediated Iminyl Radical Generation from Benzyl Oxime Ether: Synthesis of Pyrroline via Hydroimination Cyclization.
Usami K, Yamaguchi E, Tada N, Itoh A
Org Lett. 2018 Sep 21; 20(18)5714-5717. doi: 10.1021/acs.orglett.8b02429.

PMID:
    30188723
    [PubMed - in process]
Related citations


Influence of sevoflurane anesthesia with mechanical ventilation and fluid-therapy on distribution of subcutaneously administered robenacoxib in dogs.
Oyama N, Sano T, Yamamori M, Tamura J, Umar MA, Endo Y, Ishikawa Y, Itoh A, Miyoshi K, Yamashita K
J Vet Med Sci. 2018 Sep 26; 80(9)1450-1455. doi: 10.1292/jvms.17-0356.

PMID:
    30078791
    [PubMed - in process]
Related citations


The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ
Nat Med. 2018 Aug; 24(8)1234-1245. doi: 10.1038/s41591-018-0059-x.

PMID:
    29892064
    [PubMed - in process]
Related citations


Healthcare Resource Use and Cost Implications in the MOMENTUM 3 Long-Term Outcome Study.
Mehra MR, Salerno C, Cleveland JC, Pinney S, Yuzefpolskaya M, Milano CA, Itoh A, Goldstein DJ, Uriel N, Gulati S, Pagani FD, John R, Adamson R, Bogaev R, Thohan V, Chuang J, Sood P, Goates S, Silvestry SC
Circulation. 2018 Oct 30; 138(18)1923-1934. doi: 10.1161/CIRCULATIONAHA.118.035722.

PMID:
    29807933
    [PubMed - in process]
Related citations


Outcomes and Predictors of Early Infection after Heart Transplantation.
Shultes KC, Shuster JE, Micek S, Vader JM, Balsara K, Itoh A, Tellor BR
Surg Infect (Larchmt). 2018 Jul; 19(5)516-522. doi: 10.1089/sur.2017.295.

PMID:
    29775554
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of Clinical Outcomes with Phosphodiesterase-5 Inhibitor Therapy for Right Ventricular Dysfunction After Left Ventricular Assist Device Implantation.
Roberts KL, Shuster JE, Britt NS, Balsara KR, Graetz TJ, Helwani M, Itoh A, Tellor BR
ASAIO J. 2018 May 7; doi: 10.1097/MAT.0000000000000809.

PMID:
    29750687
    [PubMed - as supplied by publisher]
Related citations


Clinical Outcomes and Reduced Pulmonary Artery Pressure With Intra-Aortic Balloon Pump During Central Extracorporeal Life Support.
Tepper S, Garcia MB, Fischer I, Ahmed A, Khan A, Balsara KR, Masood MF, Itoh A
ASAIO J. 2018 Mar 30; doi: 10.1097/MAT.0000000000000788.

PMID:
    29613887
    [PubMed - as supplied by publisher]
Related citations


Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus.
Itoh A, Sadanari H, Takemoto M, Matsubara K, Daikoku T, Murayama T
Microbiol Immunol. 2018 May; 62(5)341-347. doi: 10.1111/1348-0421.12590.

PMID:
    29603339
    [PubMed - indexed for MEDLINE]
Related citations


Rituximab Induced Pulmonary Edema Managed with Extracorporeal Life Support.
Miller JR, Isakow W, Masood MF, Aguilar P, Sanfilippo KM, Balsara KR, Itoh A
Case Rep Crit Care. 2018; 20186039045. doi: 10.1155/2018/6039045.

PMID:
    29593914
    [PubMed]
Related citations


Are patterns of fine-scale spatial genetic structure consistent between sites within tropical tree species?
Smith JR, Ghazoul J, Burslem DFRP, Itoh A, Khoo E, Lee SL, Maycock CR, Nanami S, Ng KKS, Kettle CJ
PLoS One. 2018; 13(3)e0193501. doi: 10.1371/journal.pone.0193501.

PMID:
    29547644
    [PubMed - indexed for MEDLINE]
Related citations


Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure.
Mehra MR, Goldstein DJ, Uriel N, Cleveland JC Jr, Yuzefpolskaya M, Salerno C, Walsh MN, Milano CA, Patel CB, Ewald GA, Itoh A, Dean D, Krishnamoorthy A, Cotts WG, Tatooles AJ, Jorde UP, Bruckner BA, Estep JD, Jeevanandam V, Sayer G, Horstmanshof D, Long JW, Gulati S, Skipper ER, O'Connell JB, Heatley G, Sood P, Naka Y, MOMENTUM 3 Investigators.
N Engl J Med. 2018 Apr 12; 378(15)1386-1395. doi: 10.1056/NEJMoa1800866.

PMID:
    29526139
    [PubMed - indexed for MEDLINE]
Related citations


Internal driveline damage under the costal margin several years after HeartMate II implant: a series of three cases.
Ogawa M, Masood MF, Ewald GA, Vader JM, LaRue SJ, Cheng A, Balsara KR, Itoh A
J Artif Organs. 2018 Sep; 21(3)359-362. doi: 10.1007/s10047-018-1029-2.

PMID:
    29502323
    [PubMed - indexed for MEDLINE]
Related citations


Diagnosis of LVAD Thrombus using a High-Avidity Fibrin-Specific <sup>99m</sup>Tc Probe.
Cui G, Akers WJ, Scott MJ, Nassif M, Allen JS, Schmieder AH, Paranandi KS, Itoh A, Beyder DD, Achilefu S, Ewald GA, Lanza GM
Theranostics. 2018; 8(4)1168-1179. doi: 10.7150/thno.20271.

PMID:
    29464007
    [PubMed - in process]
Related citations


Photoinduced Generation of Acyl Radicals from Simple Aldehydes, Access to 3-Acyl-4-arylcoumarin Derivatives, and Evaluation of Their Antiandrogenic Activities.
Kawaai K, Yamaguchi T, Yamaguchi E, Endo S, Tada N, Ikari A, Itoh A
J Org Chem. 2018 Feb 16; 83(4)1988-1996. doi: 10.1021/acs.joc.7b02933.

PMID:
    29327585
    [PubMed - indexed for MEDLINE]
Related citations

Areas of Research Interest

Clinical results in patients with LVAD, mitral valve dynamics after mitral valve repair, myocardial strain and structural alteration in heart disease