Patient Portal

Akinobu Itoh, MD, PhD

Assistant Professor, Surgery
Division of Cardiothoracic Surgery

Specialty Areas

Cardiac Surgery
Heart Transplantation
Heart Failure / Transplant

Board Certifications

Japanese Board of Surgery
Japanese Board of Cardiovascular Surgery

Hospital Affiliations

Barnes-Jewish Hospital

Languages

Japanese

Areas of Clinical Interest

Heart valve repair/replacement, aortic root surgery, coronary artery bypass (bilateral IMA and off pump surgery),heart transplantation, mechanical assist device (LVAD/ECMO) for heart failure, pre/post operative patient care

  • Location(s)
  • Education
  • Publication & Research
  • In the News

Location(s)

Location(s)

Center for Advanced Medicine
Heart & Vascular Center

4921 Parkview Place
St. Louis, MO 63110

Suite: A
Floor: 8
Office Phone: (314) 362-8008
Fax: (314) 747-4216

Education

Education

Medical Degree: Tohoku School of Medicine, Sendai, Japan 1992
PhD : Mitral valve physiology and pathology, Tohoku School of Medicine, Sendai, Japan 2010
Residency: General Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2000
Residency: Cardiovascular Surgery, NTT Medical Center of Tokyo, Tokyo, Japan 2002
Fellowship (Research): Carl and Leah McConnell Cardiovascula Surgical Research, Stanford University School of Medicine, Stanford, CA 2008
Fellowship: Cardiovascular Surgery, St. Michael's Hospital, Toronto, Ontario 2011
Fellowship: Transplant / Heart Failure, St Michael's Hospital, Toronto, Ontario 2012

Publication & Research

Publication & Research

Inhibitory effects of 4-hydroperoxy-2-decenoic acid ethyl ester on phorbol ester- and TGF-β1-induced MMPs expression.
Kamiya T, Tanaka M, Hara H, Yamaguchi E, Itoh A, Adachi T
Free Radic Res. 2019 Oct 14; 1-9. doi: 10.1080/10715762.2019.1675874.

PMID:
    31575304
    [PubMed - as supplied by publisher]
Related citations


<i>trans</i>-Diastereoselective Syntheses of γ-Lactones by Visible Light-Iodine-Mediated Carboesterification of Alkenes.
Maejima S, Yamaguchi E, Itoh A
ACS Omega. 2019 Mar 31; 4(3)4856-4870. doi: 10.1021/acsomega.9b00333.

PMID:
    31459670
    [PubMed]
Related citations


Visible Light/Molecular-Iodine-Mediated Intermolecular Spirolactonization Reaction of Olefins with Cyclic Ketones.
Maejima S, Yamaguchi E, Itoh A
J Org Chem. 2019 Aug 2; 84(15)9519-9531. doi: 10.1021/acs.joc.9b01081.

PMID:
    31131602
    [PubMed]
Related citations


A Fully Magnetically Levitated Left Ventricular Assist Device - Final Report.
Mehra MR, Uriel N, Naka Y, Cleveland JC Jr, Yuzefpolskaya M, Salerno CT, Walsh MN, Milano CA, Patel CB, Hutchins SW, Ransom J, Ewald GA, Itoh A, Raval NY, Silvestry SC, Cogswell R, John R, Bhimaraj A, Bruckner BA, Lowes BD, Um JY, Jeevanandam V, Sayer G, Mangi AA, Molina EJ, Sheikh F, Aaronson K, Pagani FD, Cotts WG, Tatooles AJ, Babu A, Chomsky D, Katz JN, Tessmann PB, Dean D, Krishnamoorthy A, Chuang J, Topuria I, Sood P, Goldstein DJ, MOMENTUM 3 Investigators.
N Engl J Med. 2019 Apr 25; 380(17)1618-1627. doi: 10.1056/NEJMoa1900486.

PMID:
    30883052
    [PubMed - indexed for MEDLINE]
Related citations


Synthesis, Characterization, and Reactivity of an Ethynyl Benziodoxolone (EBX)-Acetonitrile Complex.
Yudasaka M, Shimbo D, Maruyama T, Tada N, Itoh A
Org Lett. 2019 Feb 15; 21(4)1098-1102. doi: 10.1021/acs.orglett.9b00005.

PMID:
    30707031
    [PubMed]
Related citations


Simultaneous Determination of Cr, As, Se, and Other Trace Metal Elements in Seawater by ICP-MS with Hybrid Simultaneous Preconcentration Combining Iron Hydroxide Coprecipitation and Solid Phase Extraction Using Chelating Resin.
Itoh A, Ono M, Suzuki K, Yasuda T, Nakano K, Kaneshima K, Inaba K
Int J Anal Chem. 2018; 20189457095. doi: 10.1155/2018/9457095.

PMID:
    30538748
    [PubMed]
Related citations


Subregional heterogeneity of somatosensory dysfunction in the insula.
Matsuda K, Satoh M, Tabei KI, Ueda Y, Itoh A, Ishikawa H, Matsuo K, Shindo A, Asahi M, Niwa A, Matsuura K, Tomimoto H
J Neurol Neurosurg Psychiatry. 2019 Aug; 90(8)957-958. doi: 10.1136/jnnp-2018-319174.

PMID:
    30455405
    [PubMed - in process]
Related citations


Galectin-9 induces atypical ubiquitination leading to cell death in PC-3 prostate cancer cells.
Itoh A, Nonaka Y, Ogawa T, Nakamura T, Nishi N
Glycobiology. 2019 Jan 1; 29(1)22-35. doi: 10.1093/glycob/cwy099.

PMID:
    30383222
    [PubMed - indexed for MEDLINE]
Related citations


Heterologous production of free dihomo-γ-linolenic acid by Aspergillus oryzae and its extracellular release via surfactant supplementation.
Tamano K, Cox RS 3rd, Tsuge K, Miura A, Itoh A, Ishii J, Tamura T, Kondo A, Machida M
J Biosci Bioeng. 2019 Apr; 127(4)451-457. doi: 10.1016/j.jbiosc.2018.09.013.

PMID:
    30327168
    [PubMed - indexed for MEDLINE]
Related citations


Induction of Human-Lung-Cancer-A549-Cell Apoptosis by 4-Hydroperoxy-2-decenoic Acid Ethyl Ester through Intracellular ROS Accumulation and the Induction of Proapoptotic CHOP Expression.
Kamiya T, Watanabe M, Hara H, Mitsugi Y, Yamaguchi E, Itoh A, Adachi T
J Agric Food Chem. 2018 Oct 17; 66(41)10741-10747. doi: 10.1021/acs.jafc.8b04424.

PMID:
    30296076
    [PubMed - indexed for MEDLINE]
Related citations


Olefin Bifunctionalization: A Visible-light Photoredox-catalyzed Aryl Alkoxylation of Olefins.
Yamaguchi E, Tanaka W, Itoh A
Chem Asian J. 2019 Jan 4; 14(1)121-124. doi: 10.1002/asia.201801211.

PMID:
    30251357
    [PubMed]
Related citations


Effects of gem-dihydroperoxides against mutant copper‑zinc superoxide dismutase-mediated neurotoxicity.
Ueda T, Inden M, Asaka Y, Masaki Y, Kurita H, Tanaka W, Yamaguchi E, Itoh A, Hozumi I
Mol Cell Neurosci. 2018 Oct; 92177-184. doi: 10.1016/j.mcn.2018.09.001.

PMID:
    30193933
    [PubMed - indexed for MEDLINE]
Related citations


Visible-Light-Mediated Iminyl Radical Generation from Benzyl Oxime Ether: Synthesis of Pyrroline via Hydroimination Cyclization.
Usami K, Yamaguchi E, Tada N, Itoh A
Org Lett. 2018 Sep 21; 20(18)5714-5717. doi: 10.1021/acs.orglett.8b02429.

PMID:
    30188723
    [PubMed]
Related citations


Influence of sevoflurane anesthesia with mechanical ventilation and fluid-therapy on distribution of subcutaneously administered robenacoxib in dogs.
Oyama N, Sano T, Yamamori M, Tamura J, Umar MA, Endo Y, Ishikawa Y, Itoh A, Miyoshi K, Yamashita K
J Vet Med Sci. 2018 Sep 26; 80(9)1450-1455. doi: 10.1292/jvms.17-0356.

PMID:
    30078791
    [PubMed - indexed for MEDLINE]
Related citations


The human heart contains distinct macrophage subsets with divergent origins and functions.
Bajpai G, Schneider C, Wong N, Bredemeyer A, Hulsmans M, Nahrendorf M, Epelman S, Kreisel D, Liu Y, Itoh A, Shankar TS, Selzman CH, Drakos SG, Lavine KJ
Nat Med. 2018 Aug; 24(8)1234-1245. doi: 10.1038/s41591-018-0059-x.

PMID:
    29892064
    [PubMed - indexed for MEDLINE]
Related citations


Healthcare Resource Use and Cost Implications in the MOMENTUM 3 Long-Term Outcome Study.
Mehra MR, Salerno C, Cleveland JC, Pinney S, Yuzefpolskaya M, Milano CA, Itoh A, Goldstein DJ, Uriel N, Gulati S, Pagani FD, John R, Adamson R, Bogaev R, Thohan V, Chuang J, Sood P, Goates S, Silvestry SC
Circulation. 2018 Oct 30; 138(18)1923-1934. doi: 10.1161/CIRCULATIONAHA.118.035722.

PMID:
    29807933
    [PubMed - indexed for MEDLINE]
Related citations


Outcomes and Predictors of Early Infection after Heart Transplantation.
Shultes KC, Shuster JE, Micek S, Vader JM, Balsara K, Itoh A, Tellor BR
Surg Infect (Larchmt). 2018 Jul; 19(5)516-522. doi: 10.1089/sur.2017.295.

PMID:
    29775554
    [PubMed - indexed for MEDLINE]
Related citations


Evaluation of Clinical Outcomes with Phosphodiesterase-5 Inhibitor Therapy for Right Ventricular Dysfunction After Left Ventricular Assist Device Implantation.
Roberts KL, Shuster JE, Britt NS, Balsara KR, Graetz TJ, Helwani M, Itoh A, Tellor BR
ASAIO J. 2019 Mar/Apr; 65(3)264-269. doi: 10.1097/MAT.0000000000000809.

PMID:
    29750687
    [PubMed - in process]
Related citations


Clinical Outcomes and Reduced Pulmonary Artery Pressure With Intra-Aortic Balloon Pump During Central Extracorporeal Life Support.
Tepper S, Garcia MB, Fischer I, Ahmed A, Khan A, Balsara KR, Masood MF, Itoh A
ASAIO J. 2019 Feb; 65(2)173-179. doi: 10.1097/MAT.0000000000000788.

PMID:
    29613887
    [PubMed - in process]
Related citations


Tricin inhibits the CCL5 induction required for efficient growth of human cytomegalovirus.
Itoh A, Sadanari H, Takemoto M, Matsubara K, Daikoku T, Murayama T
Microbiol Immunol. 2018 May; 62(5)341-347. doi: 10.1111/1348-0421.12590.

PMID:
    29603339
    [PubMed - indexed for MEDLINE]
Related citations

In the News

Areas of Research Interest

Clinical results in patients with LVAD, mitral valve dynamics after mitral valve repair, myocardial strain and structural alteration in heart disease