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Faculty Physicians

Aaron Hamvas, MD

James Keating Professor of Pediatrics
Medical Director, Newborn Intensive Care Unit, St. Louis Children's Hospital

Specialty Areas

Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Board Certifications

Neonatal-Perinatal Medicine
Pediatrics

Areas of Clinical Interest

Surfactant protein B deficency, surfactant metabolism, genetic lung disease in newborns, epidemiology of infant mortality, high frequency mentilation, premature infants, respiratory distress syndrome, low birth weight, influence of the intestinal microbiome on newborn respiratory disease.

  • Maps & Directions
  • Education
  • Publication & Research

Maps & Directions

Maps & Directions

St. Louis Children’s Hospital

1 Children’s Place
St. Louis, MO 63110

Suite: Neonatal Intensive Care Unit (NICU), 5th Floor
Office Phone: 314-454-6148
Fax: 314-454-4633

Education

Education

Fellowship: Newborn Medicine, Washington Univeristy School of Medicine, St Louis, MO (St. Louis Children's Hosp) 1990
Residency: Pediatrics, Washington University School of Medicine, St. Louis, Mo (St. Louis Children's Hospital) 1984
Medical Degree: Washington University School of Medicine, St Louis, Missouri 1981
B.S.: Rensselaer Polytechnic Institute, Troy, New York 1977

Publication & Research

Publication & Research

Ventilatory control and supplemental oxygen in premature infants with apparent chronic lung disease.
Coste F, Ferkol T, Hamvas A, Cleveland C, Linneman L, Hoffman J, Kemp J
Arch Dis Child Fetal Neonatal Ed. 2015 May; 100(3)F233-7. doi: 10.1136/archdischild-2014-307272.

PMID:
    25716677
    [PubMed - indexed for MEDLINE]
Related citations


Patterned progression of bacterial populations in the premature infant gut.
La Rosa PS, Warner BB, Zhou Y, Weinstock GM, Sodergren E, Hall-Moore CM, Stevens HJ, Bennett WE Jr, Shaikh N, Linneman LA, Hoffmann JA, Hamvas A, Deych E, Shands BA, Shannon WD, Tarr PI
Proc Natl Acad Sci U S A. 2014 Aug 26; 111(34)12522-7. doi: 10.1073/pnas.1409497111.

PMID:
    25114261
    [PubMed - indexed for MEDLINE]
Related citations


Genotype-phenotype correlations for infants and children with ABCA3 deficiency.
Wambach JA, Casey AM, Fishman MP, Wegner DJ, Wert SE, Cole FS, Hamvas A, Nogee LM
Am J Respir Crit Care Med. 2014 Jun 15; 189(12)1538-43. doi: 10.1164/rccm.201402-0342OC.

PMID:
    24871971
    [PubMed - indexed for MEDLINE]
Related citations


Sources of methodological variability in phase angles from respiratory inductance plethysmography in preterm infants.
Ulm LN, Hamvas A, Ferkol TW, Rodriguez OM, Cleveland CM, Linneman LA, Hoffmann JA, Sicard-Su MJ, Kemp JS
Ann Am Thorac Soc. 2014 Jun; 11(5)753-60. doi: 10.1513/AnnalsATS.201310-363OC.

PMID:
    24716708
    [PubMed - indexed for MEDLINE]
Related citations


Synonymous ABCA3 variants do not increase risk for neonatal respiratory distress syndrome.
Wambach JA, Wegner DJ, Heins HB, Druley TE, Mitra RD, Hamvas A, Cole FS
J Pediatr. 2014 Jun; 164(6)1316-21.e3. doi: 10.1016/j.jpeds.2014.02.021.

PMID:
    24657120
    [PubMed - indexed for MEDLINE]
Related citations


An official American Thoracic Society clinical practice guideline: classification, evaluation, and management of childhood interstitial lung disease in infancy.
Kurland G, Deterding RR, Hagood JS, Young LR, Brody AS, Castile RG, Dell S, Fan LL, Hamvas A, Hilman BC, Langston C, Nogee LM, Redding GJ, American Thoracic Society Committee on Childhood Interstitial Lung Disease (chILD) and the chILD Research Network
Am J Respir Crit Care Med. 2013 Aug 1; 188(3)376-94. doi: 10.1164/rccm.201305-0923ST.

PMID:
    23905526
    [PubMed - indexed for MEDLINE]
Related citations


Feasibility and reproducibility of systolic right ventricular strain measurement by speckle-tracking echocardiography in premature infants.
Levy PT, Holland MR, Sekarski TJ, Hamvas A, Singh GK
J Am Soc Echocardiogr. 2013 Oct; 26(10)1201-13. doi: 10.1016/j.echo.2013.06.005.

PMID:
    23880052
    [PubMed - indexed for MEDLINE]
Related citations


Diffuse lung disease in children: summary of a scientific conference.
Hamvas A, Deterding R, Balch WE, Schwartz DA, Albertine KH, Whitsett JA, Cardoso WV, Kotton DN, Kourembanas S, Hagood JS
Pediatr Pulmonol. 2014 Apr; 49(4)400-9. doi: 10.1002/ppul.22805.

PMID:
    23798474
    [PubMed - indexed for MEDLINE]
Related citations


Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain.
Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P
Hum Mutat. 2013 Jun; 34(6)801-11. doi: 10.1002/humu.22313.

PMID:
    23505205
    [PubMed - indexed for MEDLINE]
Related citations


Heterogeneous pulmonary phenotypes associated with mutations in the thyroid transcription factor gene NKX2-1.
Hamvas A, Deterding RR, Wert SE, White FV, Dishop MK, Alfano DN, Halbower AC, Planer B, Stephan MJ, Uchida DA, Williames LD, Rosenfeld JA, Lebel RR, Young LR, Cole FS, Nogee LM
Chest. 2013 Sep; 144(3)794-804. doi: 10.1378/chest.12-2502.

PMID:
    23430038
    [PubMed - indexed for MEDLINE]
Related citations


[Pulmonary surfactant associated gene variants in mixed ethnic population of Han and Zhuang].
Chen YJ, Chen SK, DePass K, Wegner DJ, Hamvas A, Nong GM, Wang YZ, Fan X, Luo JS
Zhonghua Er Ke Za Zhi. 2012 Nov; 50(11)843-6.

PMID:
    23302616
    [PubMed - indexed for MEDLINE]
Related citations


Single ABCA3 mutations increase risk for neonatal respiratory distress syndrome.
Wambach JA, Wegner DJ, Depass K, Heins H, Druley TE, Mitra RD, An P, Zhang Q, Nogee LM, Cole FS, Hamvas A
Pediatrics. 2012 Dec; 130(6)e1575-82. doi: 10.1542/peds.2012-0918.

PMID:
    23166334
    [PubMed - indexed for MEDLINE]
Related citations


Novel methods for assessment of right heart structure and function in pulmonary hypertension.
Singh GK, Levy PT, Holland MR, Hamvas A
Clin Perinatol. 2012 Sep; 39(3)685-701. doi: 10.1016/j.clp.2012.06.002.

PMID:
    22954276
    [PubMed - indexed for MEDLINE]
Related citations


Current technology in the diagnosis of developmentally related lung disorders.
Hamvas A
Neonatology. 2012; 101(4)353-9. doi: 10.1159/000337356.

PMID:
    22940625
    [PubMed - indexed for MEDLINE]
Related citations


A method to determine the kinetics of multiple proteins in human infants with respiratory distress syndrome.
Bereman MS, Tomazela DM, Heins HS, Simonato M, Cogo PE, Hamvas A, Patterson BW, Cole FS, MacCoss MJ
Anal Bioanal Chem. 2012 Jun; 403(8)2397-402. doi: 10.1007/s00216-012-5953-3.

PMID:
    22526637
    [PubMed - indexed for MEDLINE]
Related citations


An intronic ABCA3 mutation that is responsible for respiratory disease.
Agrawal A, Hamvas A, Cole FS, Wambach JA, Wegner D, Coghill C, Harrison K, Nogee LM
Pediatr Res. 2012 Jun; 71(6)633-7. doi: 10.1038/pr.2012.21.

PMID:
    22337229
    [PubMed - indexed for MEDLINE]
Related citations


Increased risk for respiratory distress among white, male, late preterm and term infants.
Anadkat JS, Kuzniewicz MW, Chaudhari BP, Cole FS, Hamvas A
J Perinatol. 2012 Oct; 32(10)780-5. doi: 10.1038/jp.2011.191.

PMID:
    22222548
    [PubMed - indexed for MEDLINE]
Related citations


Bacterial DNA content in the intestinal wall from infants with necrotizing enterocolitis.
Bucher BT, McDuffie LA, Shaikh N, Tarr PI, Warner BB, Hamvas A, White FV, Erwin CR, Warner BW
J Pediatr Surg. 2011 Jun; 46(6)1029-33. doi: 10.1016/j.jpedsurg.2011.03.026.

PMID:
    21683193
    [PubMed - indexed for MEDLINE]
Related citations


Pilot trial of late booster doses of surfactant for ventilated premature infants.
Merrill JD, Ballard PL, Courtney SE, Durand DJ, Hamvas A, Hibbs AM, Lu KW, Ryan RM, Reynolds AM, Spence K, Steinhorn RH, Truog WE, Eichenwald EC, Ballard RA
J Perinatol. 2011 Sep; 31(9)599-606. doi: 10.1038/jp.2010.210.

PMID:
    21311500
    [PubMed - indexed for MEDLINE]
Related citations


The age of necrotizing enterocolitis onset: an application of Sartwell's incubation period model.
González-Rivera R, Culverhouse RC, Hamvas A, Tarr PI, Warner BB
J Perinatol. 2011 Aug; 31(8)519-23. doi: 10.1038/jp.2010.193.

PMID:
    21273988
    [PubMed - indexed for MEDLINE]
Related citations