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Neurology / Pediatric

Robin C. C. Ryther, MD, PhD

Current Position
Assistant Professor, Neurology

Specialty Areas
Pediatric Neurology
Pediatric Epilepsy

Patients Seen At
St Louis Children’s Hospital
One Children’s Place, Suites C and D, 2nd Floor
St. Louis, MO  63110
(314) 454-6120
Fax:   (314) 454-2523
View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Neurology
Campus Box 8111, 660 S. Euclid Ave.
St. Louis, MO  63110

Areas of Clinical Interest
Pediatric refractory epilepsy, epilepsy surgery, and new onset seizures; Rett Syndrome and early epileptic encephalopathie

Board Certification
Neurology with Special Qualification in Child Neurology -- Certified

Medical Education
Bachelor of Science: University of Missouri, Columbia, Missouri, 1998
PhD: Vanderbilt University, Nashville, Tennessee, 2004
Medical Degree: Vanderbilt University, Nashville, Tennessee, 2006
Residency: Pediatrics, Massachusetts General Hospital for Children, Boston, Massachusetts, 2008
Residency: Child Neurology, Massachusetts General Hospital and Brigham and Women's Hospital, Boston Massachusetts, 2011
Fellowship: Neurophysiology and Pediatric Epilepsy, Washington University School of Medicine, St. Louis, Missouri, 2013
Hospital Affiliations
St. Louis Children's Hospital

Selected Publications and Presentations
Larson AM, Ryther RC, Jennesson M, Geffrey AL, Bruno PL, Anagnos CJ, Shoeb AH, Thibert RL, Thiele EA.  Impact of pediatric epilepsy on sleep patterns and behaviors in children and parents.  Epilepsia.  2012 July;53(7):1162-9.  

Ryther RC and Wong M.  Mammalian target of rapamycin (mTOR) inhibition:  potential for antiseizure, antiepileptogenic, and epileptostatic therapy.  Curr Neurol Neurosci Rep.  2012 Aug;12(4):410-8.

Ryther RC, Cho-Park YA, and Lee JW.  Carotid dissection in mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes.  J Neurol.  2011 May;258(5):912-4.   

Klein JP and Ryther RC.  Central Nervous System Hemorrhage.  NEJM.  2009 Oct:361:18.

Shariat N, Ryther RC, Phillips JA 3rd, Robinson, IC, Patton JG.  Rescue of Pituitary Function in a Mouse Model of Isolated Growth Hormone Deficiency Type II by RNA Interference.  Endocrinology.  2007 Feb;149(2):580-6.

Ryther RC, Flynt AS, Phillips JA 3rd, Patton JG. siRNA therapeutics: big potential from small RNAs.  Gene Ther. 2005 Jan;12(1):5-11.

Ryther RC, Flynt AS, Harris BD, Phillips JA 3rd, Patton JG. GH1 splicing is regulated by multiple enhancers whose mutation produces a dominant-negative GH isoform that can be degraded by allele-specific small interfering RNA (siRNA).  Endocrinology. 2004 Jun;145(6):2988-96.

Ryther RC, McGuinness LM, Phillips JA 3rd, Moseley CT, Magoulas CB, Robinson IC, Patton JG. Disruption of exon definition produces a dominant-negative growth hormone isoform that causes somatotroph death and IGHD II.  Hum Genet. 2003 Jul;113(2):140-8.

Abou-Khalil B, Ge Q, Desai R, Ryther R, Bazyk A, Bailey R, Haines JL, Sutcliffe JS, George AL Jr. Partial and generalized epilepsy with febrile seizures plus and a novel SCN1A mutation.  Neurology. 2001 Dec 26;57(12):2265-72.


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