Obstetrics and Gynecology / Ultrasound and Genetic Diagnosis

Washington University physicians in the Department of Obstetrics and Gynecology treat women in the following areas of practice, gynecologic cancer, general obstetrics and gynecology, maternal-fetal and ultrasound, urogynecology, reproductive endocrinology and infertility, including pediatric and adolescent gynecology.

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James P. Crane, MD

Specialty Areas
Genetics - Obstetrics
Ultrasound
Prenatal Diagnosis

Areas of Clinical Interest
Genetic amniocentesis, prenatal ultrasound, ultrasound screening, Down syndrome, neural tube defects, obstetric ultrasound, prenatal diagnosis, birth defects, fetal anomalies, congenital malformations, amniotic fluid mosaicism, chorionic villus sampling, fetal chromosome abnormalities, ob/gyn, women's health, hereditary diseases

Major or Recent Publications/Awards

Honors and Awards
Listed in Best Doctors in America, 2003 - 2009 (Best Doctors, Inc)
St. Louis Business Journal Health Hero Award, 2007
Washington University Second Century Award, 2006
Washington University Medical Alumni Distinguished Service Award, 2004

Editor/Reviewer
Associate Editor
Journal of Ultrasound in Medicine

Reviewer
American Journal of Obstetrics & Gynecology
Obstetrics and Gynecology
American Journal of Medical Genetics
Prenatal Diagnosis
Pediatric Research
Journal of Clinical Ultrasound
New England Journal of Medicine
Investigative Radiology

Selected Journal Articles / Book Chapters

Cahill AG, Macones GA, Stamilio DM, Dicke JM, Crane JP, Odibo AO. Pregnancy loss rate after mid-trimester amniocentesis in twin pregnancies. American J of Obstetrics & Gynecology 2009;200(3):257.e1-257.e6

Odibo AO, Dicke JM, Gray DL, Oberle B, Stamilio DM, Macones GA, Crane JP. Evaluating the rate and risk factors for fetal loss after chorionic villus sampling. Obstetrics & Gynecology 2008; 112:813-819

Odibo AO, Gray DL, Dicke JM, Stamilo DM, Macones GA, Crane JP. Revisiting the fetal loss rate after second trimester genetic amniocentesis: A single center's 16 year experience. Obstetrics & Gynecology 2008; 111:589-595

Filly RA, Crane JP. Routine Obstetric Sonography. J Ultrasound Med 2002; 21:713-718

Crane J: Physician Integration. Anatomy of a Merger: BJC Health System. Am College of Healthcare Executives. Health Administration Press. 1997

Ball RH, Ade CM, Schoenborn JA, Crane JP. The clinical significance of sonographically detected subchorionic hemorrhages. Am J Obstet Gynecol 1996; 174:996-1002

Gray DL, Winborn RC, Suessen TL, Crane JP. Is genetic amniocentesis warranted when isolated choroid plexus cysts are found? Prenat Diag 1996; 16:983-990

Gray DL, Crane JP. Optimal nuchal skinfold thresholds based on gestational age for prenatal detection of Down syndrome. Am J Obstet Gynecol 1994; 171:1282-1286

Crane JP, LeFevre ML, Winborn RC, Evans JK, Ewigman BG, Bain RP, Frigoletto FD, McNellis D. A randomized trial of prenatal ultrasound screening: Impact on the detection, management and outcome of anomalous fetuses. Am J Obstet Gynecol 1994; 171(2):392-399

Suessen TL, Winborn RC, Crane J. The continuing saga of fetal choroid plexus (CP) cysts -- is genetic amniocentesis warranted? 37th Annual Meeting, American Institute of Ultrasound in Medicine, Honolulu, HI, 1993

Ewigman BG, Crane JP, Frigoletto FD, LeFevre ML, Bain RO, McNellis D, et al. Impact of prenatal ultrasound screening on perinatal outcome. NEJM 1993; 329:821-827

Corteville JE, Dicke JM, Crane J. Fetal pyelectasis and Down syndrome: Is genetic amniocentesis warranted? Obstet Gynecol 1992; 79:770-772

Dicke JM, Crane J. Sonographically detected hyperechoic fetal bowel -- features and outcome of 30 cases. 36th Annual Meeting, American Institute of Ultrasound in Medicine, San Diego, CA, 1992

Schoenborn JA, Ade CM, Crane J. Clinical significance of sonographically-detected subchorionic hemorrhage. 36th Annual Meeting, American Institute of Ultrasound in Medicine, San Diego, CA, 1992

Gray DL, Crane J: Selection of optimal nuchal skinfold thickness based on gestational age as a screen for Down's syndrome. 36th Annual Meeting, American Institute of Ultrasound in Medicine, San Diego, CA, 1992

Gray D, Crane J, Johnson C. Ultrasound vs amniocentesis for evaluation of pregnancies at risk for neural tube defects. 8th International Congress of Human Genetics, Washington, DC, 1991

Corteville JE, Gray DL, Crane J. Congenital hydronephrosis: Prenatal sonographic findings predictive of postnatal outcome. Am J Obstet Gynecol 1991; 165:384-88

Cheung S, Crane J. Multiple cell-multiple flask/colony amniotic fluid mosaicism does not always indicate true fetal mosaicism. 8th International Congress of Human Genetics, Washington, DC, 1991

Gray DL, Songster GS, Brungard PA, Crane J. Sonographic fetal weight estimate nomogram: A reference standard for intrauterine growth. 35th Annual Meeting, American Institute of Ultrasound in Medicine, Atlanta, GA, 1991

Gray DL, Crane J, Cheung SE, Beaver HA. CVS mosaicism confined to the placenta: No evidence for poor pregnancy outcome. 41st Annual Meeting, The American Society of Human Genetics, Cincinnati, OH, 1990

Crane J. Chorionic Villus Sampling. The Principles and Practice of Ultrasonography in Obstetrics and Gynecology. Appleton and Lange, East Norwalk, CT 1990

Nyberg DA, Crane J. Sonographic Diagnosis of Fetal Chromosome Abnormalities. Diagnostic Ultrasound of Fetal Anomalies. Yearbook Medical Publishers, Chicago 1990

Crane J, Cheung SW. An embryogenic model to explain cytogenetic inconsistencies observed in chorionic villus versus fetal tissue. Prenatal Diag 1988; 8:110-129


For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. James M. Crane

James P. Crane, MD