Radiology / Nuclear Medicine

The Washington University physicians at Mallinckrodt Institute of Radiology (MIR) have been providing clinical radiology services for nearly three quarters of a century and have earned the reputation of a radiology leader.

MIR is a large and complex radiology department—a necessity for providing top quality radiology services to our patients.

Our expert radiologists, working with skilled nurses and technologists, perform and interpret more than 600,000 examinations and procedures each year. Combine this experience and expertise with productive research and training programs and you have a top-notch radiology facility for diagnosing and treating diseases.

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Barry Alan Siegel, MD

Specialty Areas
Nuclear Medicine
Radiology

Areas of Clinical Interest
Nuclear medicine, nuclear imaging, PET, positron emission tomography, radioiodine treatment, radionuclide imaging

Major or Recent Publications/Awards

Honors and Awards

Listed in Best Doctors in America, 2002-2009 (Best Doctors, Inc)

Listed in America's Top Doctors, Castle Connolly Medical Ltd, 2002-2008

Certificate of Outstanding Leadership, American College of Radiology Imaging Network, 2006

Certificate of Outstanding Contribution, American College of Radiology Imaging Network, 2005

Most Effective Radiology Educator Award, Auntminnie.com, 2004

Georg Charles de Hevesy Nuclear Pioneer Award for Outstanding Contributions to Nuclear Medicine, Society of Nuclear Medicine, 2003

Listed in The Best Doctors in America, 1992-93; 1994-95; 1996-97; 1998-99

Listed in The Best Doctors in America: Central Region, 1996-97

Editorial Responsibilities

Editorial Board:
Journal of Computer Assisted Tomography
European Journal of Nuclear Medicine and Molecular Imaging

Senior Editor:
Molecular Imaging and Biology

Associate Editor
Journal of Nuclear Medicine

Assistant Editor (PET/CT), American Journal of Roentgenology

2Consulting Editor
Annals of Medical Sciences (Çukorova University Faculty of Medicine)

Books and Book Chapters

Siegel BA. The National Oncologic PET Registry. In: Wahl RL, ed. PET and PET/CT Imaging Categorical Course Syllabus. Oakbrook, IL. Radiological Society of North America, in press

Dehdashti F, Siegel BA. Estrogen-receptor imaging and assessing response to hormonal therapy of breast cancer. In: Price P, Shields A, eds. In Vivo Imaging of Cancer Therapy., in press

Dehdashti F, Siegel BA. Nuclear imaging of esophageal disorders. In Rice T, Patterson GA, eds. Pearson’s Esophageal Surgery, Philadelphia, Churchill Livingstone, in press

Lin LL, Dehdashti F, Siegel BA, Grigsby PW. PET and PET/CT of tumors of the female genital tract. In: von Schulthess GK, ed. Molecular Anatomic Imaging. PET-CT and SPECT-CT Integrated Modality Imaging, 2nd ed. Philadelphia, Lippincott Williams & Wilkins, 2007:427-442

Dehdashti F, Siegel BA. PET and PET/CT imaging in esophageal and gastric cancers. In: Valk PE, Delbeke D, Bailey DL, Townsend DW, Maisey MN, eds. Positron Emission Tomography. Clinical Practice. London, Springer-Verlag, 2006:165-180

Clarke M, McCartney DA, Siegel BA. Regulatory oversight. In: Schuster DP, Powers WJ, eds. Translational and Experimental Clinical Research. Philadelphia, Lippincott Williams & Wilkins, 2005:176-188

Selected Invited and Review Articles

Kelloff GJ, Sullivan DM, Wilson W, Cheson B, Juweid M, Mills GQ, Zelenetz AD, Horning SJ, Weber W, Sargent DJ, Dodd L, Korn E, Armitage J, Schilsky R, Christian M, O'connor OA, Wang SJ, Farrell AT, Pazdur R, Graham M, Wahl RL, Larson SM, Kostakoglu L, Daube-Witherspoon M, Gastonis C, Siegel BA, Shankar LK, Lee DB, Higley HR, Sigman CC, Carucci D, Timko D, Degennaro LJ, Sigal E, Barker A, Woodcock J. FDG-PET Lymphoma Demonstration Project Invitational Workshop. Acad Radiol 2007; 14:330-339

Juweid ME, Stroobants S, Hoekstra OS, Mottaghy FM, Dietlein M, Guermazi A, Wiseman GA, Kostakoglu L, Scheidhauer K, Buck A, Naumann R, Spaepan K, Hicks RJ, Weber WA, Reske SN, Schwaiger M, Schwartz LH, Zijlstra JM, Siegel BA, Cheson BD. Use of positron emission tomography (PET) for response assessment of lymphoma: consensus of the Imaging Subcommittee of International Harmonization Project (IHP) in Lymphoma. J Clin Oncol 2007; 25:571-578

Delbeke D, Coleman RE, Guiberteau MJ, Brown ML, Royal HD, Siegel BA, Townsend DW, Berland LL, Parker JA, Zubal G, Cronin V. Procedure guideline for body SPECT/CT imaging 1.0. J Nucl Med 2006; 47:1227-1234

Shankar LK, Hoffman JM, Bacharach S, Graham MM, Karp J, Lammertsma A, Larson S, Mankoff DA, Siegel BA, Van den Abeele A, Yap J, Sullivan D. Consensus recommendations for the use of 18F-FDG PET as an indicator of therapeutic response in patients in National Cancer Institute trials. J Nucl Med 2006; 47:1059-1066

Delbeke D, Coleman RE, Guiberteau MJ, Brown ML, Royal HD, Siegel BA, Townsend DW, Berland LL, Parker JA, Hubner K, Stabin MG, Zubal G, Kachelriess M, Cronin V, Holbrook S. Procedure guideline for tumor imaging with 18F-FDG PET/CT 1.0. J Nucl Med 2006; 47:885-888

Pillot G, Siegel BA, Govindan R. Prognostic significance of fluorodeoxyglucose positron emission tomography in non-small cell lung cancer: a review. J Thorac Oncol 2006; 1:152-159

Carey BP, Coleman RE, Grigsby PW, Siegel BA. Medicare coverage of PET for cervical cancer. JACR 2006; 3:19-22

Selected Journal Articles

Hillner BE, Liu D, Coleman RE, Shields AF, Gareen IF, Hanna L, Hartson Stine S, Siegel BA. The National Oncologic PET Registry (NOPR): design and analysis plan. J Nucl Med, in press

Finkelstein SE, Fernandez FG, Dehdashti F, Siegel BA, Hawkins WG, Linehan DC, Strasberg SM. Unique site and time specific patterns of recurrence following resection of colorectal carcinoma hepatic metastases in patients staged by FDG-PET. J Hepatobiliary Pancreat Surg, in press

Kidd EA, Siegel BA, Dehdashti F, Grigsby PW. The standardized uptake value for F-18 fluorodeoxyglucose (FDG) is a sensitive predictive biomarker for cervical cancer treatment response and survival. Cancer, in press

Basu D, Siegel BA, McDonald DJ, Nussenbaum B. Detection of occult bone metastases from head and neck squamous cell carcinoma: impact of PET/CT imaging. Arch Otolaryngol, in press

Lindsay MJ, Siegel BA, Tunis SR, Hillner BE, Shields AF, Carey BP, Coleman RE. The National Oncologic PET Registry: expanded Medicare coverage for PET under coverage with evidence development. AJR 2007; 188:1109-1113

Meyers BF, Downey RJ, Decker PA, Keenan RJ, Siegel BA, Cerfolio RJ, Landreneau RJ, Reed CE, Balfe DM, Dehdashti F, Ballman KV, Rusch VW, Putnam JB Jr. The utility of positron emission tomography in staging of potentially operable carcinoma of the thoracic esophagus: results of the American College of Surgeons Oncology Group Z0060 Trial. J Thorac Cardiovasc Surg 2007; 133:738-745

Ponde DE, Dence CS, Oyama N, Kim J, Tai Y-C, Laforest R, Siegel BA, Welch MJ. 18F-fluoroacetate: a potential acetate analog for prostate tumor imaging—in vivo evaluation of 18F-fluoroacetate versus 11C-acetate. J Nucl Med 2007; 48:420-428

Biehl K, Kong F-M, Dehdashti F, Jin J-Y, Mutic S, El Naqa I, Siegel BA, Bradley JD. 18F-FDG PET definition of gross tumor volume for radiotherapy of non-small cell lung cancer: is a single standardized uptake value threshold approach appropriate? J Nucl Med 2006; 47:1808-1812

Cotter SE, Grigsby PW, Siegel BA, Dehdashti F, Malyapa RS, Fleshman JW, Birnbaum EH, Wang X, Abbey E, Tan B, Kodner IJ, Hunt SB, Lowney JK, Mutch MG, Dietz DW, Myerson RJ. FDG-PET/CT in the evaluation of anal carcinoma. Int J Radiation Oncology Biol Phys 2006; 65:720-725

Posther KE, McCall LM, Harpole DH Jr, Reed CE, Putnam JB Jr, Rusch VW, Siegel BA. Yield of brain FDG-PET in evaluating patients with potentially operable non-small cell lung cancer. J Nucl Med 2006; 47:1607-1611

Meyers BF, Haddad F, Siegel BA, Zoole JB, Battafarano RJ, Veeramachaneni N, Cooper JD, Patterson GA. Cost-effectiveness of routine mediastinoscopy in computed tomography- and positron emission tomography-screened patients with stage I lung cancer. J Thorac Cardiovasc Surg 2006; 131:822-829

Xue F, Lin LL, Dehdashti F, Miller TR, Siegel BA, Grigsby PW. F-18 fluorodeoxyglucose uptake in primary cervical cancer as an indicator of prognosis after radiation therapy. Gynecol Oncol 2006; 101:145-151

Wright JD, Dehdashti F, Herzog TJ, Mutch DG, Huettner PC, Rader JS, Gibb RK, Powell MA, Gao F, Siegel BA, Grigsby PW. Preoperative nodal staging of early stage cervical carcinoma by FDG-PET. Cancer 2005; 104:2484-2491

Lamoreaux WT, Grigsby PW, Dehdashti F, Zoberi I, Powell MA, Gibb RK, Rader JS, Mutch DG, Siegel BA. FDG-PET evaluation of vaginal carcinoma. Int J Radiation Oncology Biol Phys 2005; 62:733-737

Dehdashti F, Picus J, Michalski JM, Dence CS, Siegel BA, Katzenellenbogen JA, Welch MJ. Positron tomographic assessment of androgen receptors in prostatic carcinoma. Eur J Nucl Med Mol Imaging 2005; 32:344-350

Grigsby PW, Mutch DG, Rader J, Herzog TJ, Zoberi I, Siegel BA, Dehdashti F. Lack of benefit of concurrent chemotherapy in patients with cervical cancer and negative lymph nodes by FDG-PET. Int J Radiation Oncology Biol Phys 2005; 61:444-449

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Barry Siegel

Barry Alan Siegel, MD