Internal Medicine / Endocrinology, Metabolism and Lipid Research

The Washington University physicians in the Department of Internal Medicine encompass 14 specialty clinical divisions.

Over 270 physicians in the department of medicine treat patients with a wide range of diseases, disorders and conditions.

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Clay F. Semenkovich, MD

Specialty Areas
Hyperlipidemia
Thyroid Disorders
Endocrinology
Diabetes

Major or Recent Publications/Awards

Honors and Awards

Listed in Best Doctors in America, 2002 - 2009 (Best Doctors, Inc)

Listed in America's Top Doctor's, Castle Connolly Medical Ltd, 2002 - 2008

Peer Reviewed Articles

Greiwe JS, Holloszy JO, Semenkovich CF. Exercise induces lipoprotein lipase and GLUT-4 protein in muscle independent of adrenergic-receptor signaling. J Appl Physiol 2000; Jul;89(1):176-81

Li B, Holloszy JO, Semenkovich CF. Respiratory uncoupling induces aminolevulinc acid synthase expression through a nuclear respiratory factor-1-dependent mechanism in HeLa cells. J Biol Chem 1999; 274:17534-17540

Journal Articles

Bernal-Mizrachi C, Xiaozhong L, Yin L, Knutsen RH, Howard MJ, Arends JJA, DeSantis P, Coleman T, Semenkovich CF. An afferent vagal nerve pathway links hepatic PPARá activation to glucocorticoid-induced insulin resistance and hypertension. Cell Metabolism, vol. 5:2, pp. 91-102, Feb. 2007 DOI 10.1016/j.cmet.2006.12.010

Tordjman K, Standley KN, Bernal-Mizrachi C, Leone TC, Coleman T, Kelly DP, Semenkovich CF. PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells. J Lipid Res 2002; Jun;43(6):936-43

Greiwe JS, Cheng B, Rubin DC, Yarasheski KE, Semenkovich CF. Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans. FASEB J 2001; Feb;15(2):475-82

Greiwe JS, Kwon G, McDaniel ML, Semenkovich CF. Leucine and insulin activate p70 S6 kinase through different pathways in human skeletal muscle. Am J Physiol Endocrinol Metab 2001; Sep;281(3):E466-71

Jakoby MG 4th, Semenkovich CF. The role of osteoprogenitors in vascular calcification. Curr Opin Nephrol Hypertens 2000; Jan;9(1):11-5

Greiwe JS, Holloszy JO, Semenkovich CF. Exercise induces lipoprotein lipase and GLUT-4 protein in muscle independent of adrenergic-receptor signaling. J Appl Physiol 2000; Jul;89(1):176-81

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Clay F. Semenkovich

Clay F. Semenkovich, MD