Michael P. Whyte, MD
Current Position
Professor, Medicine
Professor, Pediatrics
Professor, Genetics
Division of Bone and Mineral Diseases
Director, Center for Metabolic Bone Disease and Molecular Research, Shriners Hospitals for Children
Specialty Areas
Endocrinology
Pediatric Bone Disorders
Bone and Mineral Diseases
Inherited Disorders of Bone and Mineral Metabolism
Mailing Address
|
Washington University School of Medicine, Division of Bone & Mineral Diseases
660 South Euclid Avenue, Campus Box 8301
St. Louis,
MO
63110
|
Areas of Clinical Interest
Diagnosis and treatment of heritable disorders of bone and mineral metabolism, bone disease in adults and children, mineral disease, osteogenesis imperfecta, rickets, osteopetrosis, hypophosphatasia, hypophosphatemia, genetics, vitamin D-resistant rickets, metabolic and dysplastic bone disease in children, chondrodysplasia, pseudohypoparathyroidism, juvenile osteoporosis
Board Certification
Endocrinology & Metabolism
--
Eligible
Internal Medicine
--
Certified
Medical Education
B.A.: Chemistry, Washington Square College of Arts and Science, New York University, New York, New York
, 1968
Medical Degree: Downstate College of Medicine, State University Of New York, Brooklyn, New York
, 1972
Residency: Internal Medicine, Bellevue Hospital, New York, New York
, 1974
Clinical Associate: National Institutes of Health, Bethesda, Maryland
, 1976
Fellowship: Bone and Mineral Metabolism, Washington University School of Medicine, St. Louis, Missouri
, 1979
Hospital Affiliations
Barnes-Jewish Hospital
Shriners Hospitals for Children
St. Louis Children's Hospital
Major or Recent Publications/Awards
Awards
Listed in Best Doctors in America, 2005 - 2009 (Best Doctors, Inc)
Dr. Boy Frame Award, Adult Bone and Mineral Working Group, American Society for Bone and Mineral Research, 1997
Distinguished Medical Service Award: The Magic Foundation for Children's Growth, 1996
Who's Who In America, 1996
Who's Who In Science and Engineering, 1996
Who's Who In American Education, 1993
Fuller Albright Award, American Society for Bone and Mineral Research, 1987
Young Investigator Award, American Society for Bone and Mineral Research, 1983
Editorial Responsibilities
Editorial Board
Journal of Bone and Mineral Metabolism
Journal of Clinical Densitomotry
Books and Book Chapters
Whyte MP. Approach To The Patient With Metabolic Bone Disease. Vitamin D. (2nd Ed,) Feldman D, Glorieux F, Pike W (eds) Academic Press, San Diego, pp 913-929, 2005
US Surgeon General's Report, Contributing Author. Bone Health and Osteoporosis, 2004
Whyte MP. Osteonecrosis, Osteosclerosis And Other Disorders Of Bone. In: "Cecil Textbook of Medicine" (22nd Ed), Goldman L, Bennett JC, eds; WB Saunders Co, Philadelphia, pp 1582-1587, 2004
Journal Articles
Bowl MR, Nesbit MA, Harding B, Levy E, Jefferson A, Volpi E, Schlessinger D, Whyte MP, Thakker RV. An Interstitial Deletion-Insertion Involving Chromosomes 2p25 And Xq27, Near SOX3, Causes X-Linked Recessive Hypoparathyroidism. Journal of Clinical Investigation, 2005; 115:2822-2831
Kennedy AM, Christie PT, Harding B, Pannett AAJ, Dearlove A, Hartley Cl, Inada M, Krane SM, Whyte MP, Thakker RV. Spondyloepimetaphyseal Dysplasia Missouri Variant (SEMDMO) Maps To Chromosome 11q22.3 And Is Caused By Mutation Of Matrix Metalloproteinase 13 (MMP-13). Journal of Clinical Investigation, 2005; 115:2832-2842
Whyte MP. Misinterpretation Of Osteodensitometry With High Bone Density (BMD Z „d + 2.5 Is Not Normal¨). Journal of Clinical Densitometry 2005; 8: 1-6
Whyte MP, Essmyer K, Gannon FH, Reinus WR. Skeletal Fluorosis And Instant Tea
American Journal of Medicine 2005; 118:78-82
Watts GDJ, Wymer J, Mehta SG, Mumm S, Pestronk A, Whyte MP, Kimonis VE. Inclusion body myopathy paget bone disease - frontotemporal dementia syndrome caused by mutated valosin containing protein. Nature Genetics, 2004; 36:377-81
Whyte MP, Wenkert D, Clements KL, McAlister WH, Mumm S. Bisphosphonate-Induced Osteopetrosis. New England Journal of Medicine 2003; 349: 455-461
Whyte MP, Kurtzburg J, McAlister WH, Podgornik MN, Mumm SR, Coburn SP, Ryan LM, Miller CR, Gottesman GS, Martin PL.
Marrow cell transplantation for infantile hypophosphatasia. Journal of Bone and Mineral Research 2003; 18:624-636
Whyte MP, Obrecht SE, Finnegan PM, Jones JL, Podgornik MN, McAlister WH, Mumm S. Osteoprotegerin deficiency and juvenile Paget¡¦s Disease. New England Journal of Medicine, 2002; 347:174-184
Whyte MP, Obrecht SE, Finnegan PM, Jones JL, Podgornik MN, McAlister WH, Mumm S. Osteoprotegerin deficiency and juvenile Paget's disease. N Engl J Med 2002; Jul 18;347(3):175-84
Whyte MP, Reinus WR, Podgornik MN, Mills BG. Familial expansile osteolysis (excessive RANK effect) in a 5-generation American kindred. Medicine (Baltimore) 2002; Mar;81(2):101-21
Mumm S, Jones J, Finnegan P, Henthorn PS, Podgornik MN, Whyte MP. Denaturing gradient gel electrophoresis analysis of the tissue nonspecific alkaline phosphatase isoenzyme gene in hypophosphatasia. Mol Genet Metab 2002; Feb;75(2):143-53
Whyte MP, Hughes AE. Expansile skeletal hyperphosphatasia is caused by a 15-base pair tandem duplication in TNFRSF11A encoding RANK and is allelic
to familial expansile osteolysis. J Bone Miner Res 2002; Jan;17(1):26-9
Whyte MP, Podgornik MN, Wollberg VA, Eddy MC, McAlister WH. Pseudo-(tumor-induced) rickets. J Bone Miner Res 2001; Aug;16(8):1564-71
For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Michael P. Whyte