Neurological Surgery

Surgeons in the Department of Neurosurgery treat adult and pediatric patients with disorders of the nervous system, brain, meninges, skull, and blood supply, the extracranial carotid and vertebral arteries; brain tumors, disorders of the pituitary gland, disorders of the spinal cord, meninges, and vertebral column, including those which may require treatment by spinal fusion or instrumentation; and disorders of the cranial, spinal and peripheral nerves.

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Home > Physicians Directory > Neurological Surgery

Gregory J. Zipfel, MD

Specialty Areas
Cerebrovascular Disease
Skull Base Tumors
Aneurysms and Vascular Malformations
Pituitary Tumors
Neuro Oncology
Carotid Disease
Moyamoya Disease
Neurological Surgery
Brain Tumors
Stroke

Areas of Clinical Interest
Cerebrovascular disease including aneurysms, arteriovenous malformations, cavernous malformations, carotid stenosis, Moyamoya disease and arterial bypass surgery, skull base tumors including meningiomas, acoustic neuromas, craniofacial tumors and pituitary brain tumors.

Major or Recent Publications/Awards
Honors and Awards

Who's Who in Healthcare and Medicine (6th Edition), 2006
Charles Schanck Award, Excellence in Neurosurgery, University of Florida, 2002
M.D. with Distinction, Northwestern University Medical School, 1995
Lucien J. Rubenstein Award, Excellence in Neuro-Oncology Research, 1994

Editorial Responsibilities
Editorial Board
Internet Stroke Center

Ad Hoc Reviewer
Blood
Brain Research
Stroke

Book Chapters

Day AL, Zipfel GJ, Cawley WM. Surgical management of infraclinoid aneurysms. In: Sekhar LN, eds. Atlas of Neurological Techniques, Thieme, In press

Zipfel GJ, Day AL. Surgical treatment of paraclinoid and ophthalmic aneurysms. In: LeRoux PD & Winn HR, eds. Management of Cerebral Aneurysms, W.B. Saunders, 2003

Zipfel GJ, Day AL. Surgical treatment of intracavernous and paraclinoid internal carotid artery aneurysms. In: Winn HR, ed. Youmans Neurological Surgery, Fifth Edition, W.B. Saunders, 2003

Zipfel GJ, Day AL. Surgical treatment of paraclinoid internal carotid artery aneurysms. In: Batjer HH & Loftus CM, eds. Textbook of Neurological Surgery: Principles and Practice. Lippincott-Williams & Wilkins, 2002

Zipfel GJ, Day AL. Tandem stenotic lesions of the cervical bifurcation and siphon regions of the internal carotid artery. In: Loftus CM & KREsowik TF, eds. Textbook of Carotid Artery Surgery, Thieme, 1998, pp. 147-56

Publications

Ashley WW, Zipfel GJ, Moran CJ, Zheng J, Derdeyn CP. Moyamoya phenomenon secondary to intracranial atherosclerotic disease: Diagnosis by 3T magnetic resonance imaging. Journal of Neuroimaging (in press).

Ray WZ, Moran CJ, Derdeyn CP, Diringer MN, Dacey RG Jr., Zipfel GJ. Near complete resolution of angiographic cerebral vasospasm after extreme elevation of mean arterial pressure: Case report. Surgical Neurology (in press).

Zipfel GJ, Sagar J, Miller JP, Videen TO, Grubb RL Jr., Dacey RG Jr., Derdeyn CP. Cerebral hemodynamics as a predictor of stroke in adult Moyamoya patients: A prospective observational study. Neurosurgical Focus (accepted).

Zipfel GJ, Shah MN, Refai D, Dacey RG Jr., Derdeyn CP. Cranial dural arteriovenous fistulas: Modification of angiographic classification scales based on new natural history data. Neurosurgical Focus (accepted).

Limbrick DD, Behdad A, Derdeyn CP, Custer PL, Zipfel GJ, Santiago P. Traumatic enucleation with avulsion of the ophthalmic artery resulting in aneurysm-like subarachnoid hemorrhage and clinical course. Journal of Neurosurgery (accepted).

Strom RG, Botros JA, Refai D, Moran CJ, Cross DT III, Chicoine MR, Grubb RL, Rich KM, Dacey RG Jr., Derdeyn CP, Zipfel GJ. Cranial dural arteriovenous fistulas: asymptomatic cortical venous drainage portends less aggressive clinical course. Neurosurgery 64(2):241-7, 2009.

 Zipfel GJ, Henry BH, Ford A, Lee JM. Cerebral amyloid angiopathy: progressive disruption of the neurovascular unit. Stroke 40(supple 1):S16-S19, 2009.

Brenner MJ, Perrin RJ, Uppaluri R, Zipfel GJ, Lewis JS. Pathology quiz case: atypical meningioma with clear cell features (WHO II). Archives of Otolaryngology-Head & Neck Surgery 134(4):447, 2008.

Brody DL*, Magnoni S*, Schwetye KE, Spinner M, Esparza TJ, Stocchetti N, Zipfel GJ, Holtzman DM. Amyloid-beta dynamics correlate with neurological status in the injured human brain. Science 321:1221-1224, 2008.

Dacey RG Jr., Zipfel GJ, Ashley W, Chicoine M, Reinert M. Automated, compliant, high-flow common carotid to middle cerebral artery bypass: technical note. Journal of Neurosurgery 109(3):559-564, 2008.

Zipfel GJ. Modern management of brain aneurysms and vascular malformations. Missouri Medicine 105(5):413-419, 2008

Refai D, Botros JA, Strom RG, Derdeyn CP, Sharma A, Zipfel GJ. Spontaneous isolated convexity subarachnoid hemorrhage: presentation, radiological findings, differential diagnosis, and clinical course. Journal of Neurosurgery 109:1034-1041, 2008.

Johnston JM Jr., Chicoine MR, Dacey RG Jr., Zipfel GJ. Aneurysmal subarachnoid hemorrhage presenting with acute paraparesis: Report of six cases and review of the literature. Neurosurgery 63(6):1119-1124, 2008.

Han BH, Zhou ML, Abousaleh FS, Brendza RP, Dietrich HH, Koenigsknect-Talboo J, Cirrito JR, Milner E, Holtzman DM, Zipfel GJ. Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-b peptide, partial restoration via ?-secretase inhibition. Journal of Neuroscience 28(50):13542-13550, 2008.

Hallemeier CL, Rich KM, Grubb RL Jr, Chicoine MR, Moran CJ, Cross DT 3rd, Zipfel GJ, Dacey RG Jr, Derdeyn CP. Clinical Features and Outcome in North American Adults with Moyamoya Phenomenon. Stroke, 37(6):1490-6, 2006.

Zipfel GJ, Dacey RG Jr. Cerebral vasospasm. Neurosurgical Focus, 21(3):Introduction, 2006.

Terry A, Zipfel GJ, Milner E, Cross DT III, Moran CJ, Diringer MN, Dacey RG Jr, Derdeyn CP. Safety and technical efficacy of over-the-wire balloons for the treatment of subarachnoid hemorrhage-induced cerebral vasospasm. Neurosurgical Focus, 21(3):E14, 2006.

Zipfel GJ, Derdeyn CP, Dacey RG Jr. Current status of manpower needs for the management of cerebrovascular disease. Neurosurgery, 59(5 Suppl 3):S261-70, 2006.

Cai AL, Zipfel GJ, Sheline CT. Zinc neurotoxicity is dependent on intracellular NAD levels and the sirtuin pathway. Eur J Neurosci, 24(8):2169-2176, 2006.

Hartman RE, Lee JM, Zipfel GJ, Wozniak DF. Characterizing learning deficits and hippocampal neuron loss following transient global cerebral ischemia in rats. Brain Research 2005; 1043(1-2):48-56

Zipfel GJ, Fox DJ, Rivet DJ. Moyamoya disease in adults: the role of cerebral revascularization. Skull Base 2005; 15(1):27-41


For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Gregory F. Zipfel

Gregory J. Zipfel, MD