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Home > Physicians Directory > Surgery / General Surgery - Acute and Critical Care Surgery

Craig M. Coopersmith, MD

Specialty Areas
Emergency Surgery
General Surgery
Burn/Trauma/Surgical Critical Care

Areas of Clinical Interest
General surgery, critical care medicine, sepsis, shock, ARDS, multiple organ failure, pneumonia, hemorrhage, burns, intra-abdominal infections, complicated skin infections

Areas of Research Interest
Intestinal apoptosis in the development of shock and sepsis, Interactions between the intestine and the immune system and Nosocomial infections in the surgical intensive care unit.


Major or Recent Publications/Awards

Honors and Awards

Listed in Best Doctors in America, 2008 (Best Doctors, Inc)

2006: Teacher of the Year, Surgical and Burn/Trauma Intensive Care Unit, Barnes-Jewish Hospital

2005: BJC HealthCare System Team Quality Improvement Award (Ventilator Associated Pneumonia Prevention Team)

2004: Teacher of the Year, Surgical and Burn/Trauma Intensive Care Unit, Barnes-Jewish Hospital

2003: Research Citation Award (given to top 5 posters) Society of Critical Care Medicine

Editorial Responsibilities

Editorial Consultant, Physicians' Information and Education Resource, American College of Physicians (2007-present)
Editorial Board, Critical Care Medicine (2006-present)
Editorial Board, Shock (2005-present)

Books and Book Chapters

Coopersmith CM, Buchman TG. Perioperative management of the emergency surgery patient: the ICU and the intensivist. In: Britt L, Trunkey D, Feliciano D (eds.). Acute Care Surgery Principles and Practice. New York: Springer; 2007:67-83

Coopersmith CM. Molecular foundations of cellular injury: Apoptosis and necrosis. In: Fuhrman B, Zimmerman J (eds.). Pediatric Critical Care. St. Louis: Mosby; 2006:1444-1452

Coopersmith CM, Kollef MH. 18 Post-operative and ventilator-associated pneumonia. 7 Critical Care. In: Souba WW, Fink MP, Jurkovich GJ et al. (eds). ACS Surgery Online.. New York: WebMed Inc; 2005 http://www.acssurgery/.August 2005

Husain KD, Coopersmith CM. Acute renal failure. In: Doherty G, Mulholland M (eds.). Complications in General Surgery. Lippincott Wilkins and Williams; 2005:150-156.

Coopersmith CM, Buchman TG. Perioperative care and monitoring of the surgical patient. In: Cameron J (ed.). Current Surgical Therapy. St. Louis: Mosby; 2004: 1105-1111.Coopersmith CM, Buchman TG. Perioperative care and monitoring of the surgical patient. In: Cameron J (ed.). Current Surgical Therapy. St. Louis: Mosby; 2004: 1105-1111.

Coopersmith CM, Babcock HM, Zack J, Cobb JP. Infection Control in the Intensive Care Unit. Surgical Infections. D Fry, editor. Little, Brown and Company, Boston, 2001

Coopersmith CM, Kodner IJ. Colon, rectum, and anus. The Washington Manual of Surgery. G Doherty, J Meko, J Olson, G Peplinski, N Worrall, editors, pp. 236-258. Little, Brown and Company, Boston, 1999

Coopersmith CM, Moley JF. The Spleen. The Washington Manual of Surgery. D Baumann, L Creswell, G Doherty, J Goss, T Lairmore, editors, pp. 280-286. Little, Brown and Company, Boston, 1996

Selected Journal Articles

Vyas D, Robertson CM, Stromberg PE, Martin J, Dunne WM, Houchen CW, Barrett TA, Ayala A, Perl M, Buchman TG, Coopersmith CM. Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine. Histology and Histopathology. 2007;22:623-630.

Robertson CM, Klingensmith ME, Coopersmith CM. Long-term outcomes of performing a post-doctoral research fellowship during general surgery residency. Annals of Surgery. (in press)

Taylor BE, Schallom ME, Sona CS, Buchman TG, Boyle WA, Mazuski JE, Schuerer DE, Thomas JM, Kaiser C, Huey WY, Ward MR, Zack JE, Coopersmith CM. Efficacy and safety of an insulin infusion protocol in a surgical ICU. Journal of the American College of Surgeons. 2006;202(1):1-9. Epub 2005 Nov 18.

Husain KD, Stromberg PE, Woolsey CA, Turnbull IR, Dunne WM, Javadi P, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury. Critical Care Medicine. 2005;33(10):2350-2357.

Vyas D, Javadi P, Dipasco PJ, Buchman TG, Hotchkiss RS, Coopersmith CM. Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levels. Am J Physiol Regul Integr Comp Physiol. 2005;289(4):R1048-53. Epub 2005 Jun 9.

Javadi P, Buchman TG, Stromberg PE, Turnbull IR, Vyas D, Hotchkiss RS, Karl IE, Coopersmith CM. Iron dysregulation combined with aging prevents sepsis-induced apoptosis. Journal of Surgical Research. 2005;128(1):37-44.

Turnbull IR, Buchman TG, Javadi P, Woolsey CA, Hotchkiss RS, Karl IE, Coopersmith CM. Age disproprotionately increases sepsis-induced apoptosis in the spleen and gut epithelium. Shock. 2004;22:364-368. – lead (cover) manuscript.

Javadi P, Buchman TG, Stromberg PE, Husain KD, Dunne WM, Woolsey CA, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM. Exogenous iron following cecal ligation and puncture increases mortality in mice and is associated with an increase in gut epithelial and splenic apoptosis. Critical Care Medicine. 2004;32:1178-1185. (cover)

Turnbull IR, Javadi P, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated IL-6 levels. Shock. 2004;21:121-125. - lead (cover)

Coopersmith CM, Zack JE, Ward MR, Schallom ME, Sona CS, Everett S, Huey W, Garrison T, McDonald J, Buchman TG, Boyle WA, Fraser VJ, Polish LB. The impact of bedside behavior on catheter-related bacteremia in the intensive care unit. Archives of Surgery. 2004;139:131-136. (cover)

Taylor BE, Huey WY, Buchman TG, Boyle WA, Coopersmith CM. Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care uint. Journal of the American College of Surgeons. 2004;198:198-204.

Husain KD, Stromberg PE, Javadi, P, Buchman TG, Karl IE, Hotchkiss RS, Coopersmith CM. Bcl-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival. Shock. 2003;20:437-443.

Coopersmith CM, Stromberg PE, Davis CG, Dunne WM, Amiot DM, Karl IE, Hotchkiss RS, Buchman TG. Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest. Critical Care Medicine. 2003;31:1630-1637. - leading clinical investigation (cover).

Turnbull IR, Wizorek JJ, Osborne D, Hotchkiss RS, Coopersmith CM, Buchman TG. Effects of age on mortality and efficacy in cecal ligation and puncture. Shock. 2003;19:310-313. - lead (cover) manuscript

Coopersmith CM, Stromberg PE, Dunne WM, Davis CG, Amiot DM, Buchman TG, Karl IE, Hotchkiss RS. Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis. Journal of the American Medical Association. 2002;287:1716-1721.

Coopersmith CM, Rebmann TL, Zack JE, Ward MR, Corcoran RM, Schallom ME, Sona CS, Buchman TG, Boyle WA, Polish LB, Fraser VJ. Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit. Critical Care Medicine. 2002;30:59-64.

Coopersmith CM, Chang KC, Swanson PE, Tinsley KW, Stromberg PE, Buchman TG, Karl IE, Hotchkiss RS. Overexpression of Bcl-2 in the intestinal epithelium increases survival in septic mice. Critical Care Medicine. 2002;30:195-201.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Coopersmith