Wayne M. Yokoyama, MD
Current Position
Professor, Medicine
Division of Rheumatology
Professor, Pathology
Sam J. Levin and Audrey Loew Levin Chair for Research of Arthritis
Investigator, Howard Hughes Medical Institute
Director, Medical Scientist Training Program
Specialty Areas
Rheumatology
Rheumatoid Arthritis
Mailing Address
|
Washington University School of Medicine
Division of Rheumatology
660 South Euclid Avenue, Campus Box 8045
St. Louis,
MO
63110
|
Areas of Clinical Interest
Gene families, natural killer cells
NOT SEEING PATIENTS AT THIS TIME
Board Certification
Internal Medicine
--
Certified
Rheumatology
--
Certified
Medical Education
B.A.: University of Rochester, Rochester, New York
, 1974
Medical Degree: University Of Hawaii at Manoa, Honolulu, Hawaii
, 1978
Residency: Internal Medicine, University of Iowa Hospitals, Iowa City, Iowa
, 1981
Fellowship: Clinical, Rheumatology, University of Iowa Hopsitals, Iowa City, Iowa
, 1982
Fellowship: Research, Rheumatology, University of Iowa Hospitals, Iowa City, Iowa
, 1985
Fellowship: Research, Immunology, NIAID, NIH, Bethesda, Maryland
, 1989
Hospital Affiliations
Barnes-Jewish Hospital
Major or Recent Publications/Awards
Awards
Listed in Best Doctors in America, 2009 (Best Doctors, Inc)
Association of American Physicians (AAP), 2000
American Society for Clinical Investigation (ASCI), 1996
Basic Science Faculty Achievement Award, MSSM Committee of 1000, 1994
Editorial Responsibilities
Chair:
Editorial Review Group in Rheumatology, Doody Publishing
Advisory Board:
Journal of Experimental Medicine
Editorial Board:
Journal of Clinical Immunology
Associate Editor:
Journal of Immunology
Reviewer:
Journal of Immunology
Journal of Clinical Investigation
Cellular Immunology
Regional Immunology
European Journal of Immunogenetics
Autoimmunity
Proceedings of the National Academy of Sciences (USA)
Journal of Experimental Medicine
Immunity
Viral Immunology
Nature
Science
BioTechniques
European Journal of Immunology
Journal of Clinical Immunology
Biochimica et Biophysica Acta
Immunology Today
Blood
Genomics
The Journal of Biological Chemistry
Arthritis and Gheumatism
Journal of Leukocyte Biology
Journal of Cell Biology
Journal of Investigative Dermatology
Kidney International
Nature Immunology
Electronic Media
Liszewski MK, Yokoyama WM and Atkinson JP. II: Innate Immunity. 6 Immunology/Allergy. In ACP Medicine Online (Dale DC, Federmann DD, Eds.), New York: WebMD Inc, 2004
Books and Book Chapters
Brown MG, Scalzo A and Yokoyama WM. The NKC and Regulation of Natural Killer Cell-mediated immunity. In: Major Histocompatibility Complex: Evolution, Structure and Function (Kasahara, M., Ed.). Tokyo: Springer-Verlag 2000; 287-301
Yokoyama WM. Chapter 17. Natural Killer Cells. In: Paul WE (Ed.). Fundamental Immunology, Fourth Edition, Lippincott-Raven, New York 1999; 575-603
Peer Reviewed Articles
Yokoyama WM, Kim S. How do natural killer cells find self to achieve tolerance? Immunity 2006 Mar; 24(3):249-57
Yokoyama WM. Betting on NKT and NK cells. Immunity 2004; 20:363-365
French AR and Yokoyama WM. Natural killer cells and autoimmunity. Arthritis Res Ther 2004; 6:8-14
Carayannopoulos LN and Yokoyama WM. Recognition of infected cells by natural killer cells. Curr Opin Immunol 2004; 16:26-33
Yokoyama WM, Kim S and French AR. The dynamic life of natural killer cells. Ann Rev Immunol, 2004; 22:405-429
Yokoyama WM. Innate natural killer cell responses to infection. In The Innate Immune Response to Infection (Kaufmann, S.E., Medzhitov, R., and Gordon, S., Eds.) Philadelphia, PA: American Society for Microbiology Press, 2004; gp 133-155
Yokoyama WM and Plougastel BFM. Immune functions encoded by the natural killer gene complex. Nature Rev Immunol 2003; 3:304-316
Selected Publications
Krug A, French AR, Barchet W, Fischer JAA, Dzionek A, Pingel JT, Orihuela M, Akira S, Yokoyama WM, and Colonna M. TLR9-dependent recognition of murine cytomegalovirus (MCMV) by interferon-producing cells and dendritic cells generates a coordinated cytokine response that activates anti-viral NK cell function. Immunity 2004; 21:107-119
Bubic I, Wagner M, Krmpotic A, Saulig T, Kim S, Yokoyama WM, Jonjic S, and Koszinowski UH. Gain-of-virulence caused by loss of a gene in murine cytomegalovirus. J Virol 2004; 78:7536-7544
Warfield KL, Perkins JG, Swenson DL, Deal EM, Bosio CM, Aman MJ, Yokoyama WM, Young HA, and Bavari S. Role of natural killer cells in innate protection against lethal Ebola virus infection. J Exp Med 2004; 200:169-179
French AR, Pingel JT, Wagner M, Bubic I, Yang L, Kim S, Koszinowski U, Jonjic S and Yokoyama WM. Escape of mutant double-stranded DNA virus from innate immune control. Immunity 2004; 20:747-756
For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Yokoyama