Ellen F. Binder, MD
Associate Professor, Medicine
Division of Geriatrics and Nutritional Science
Associate Professor, Occupational Therapy
Hip Fracture Rehabilitation
Patients Seen At
Center for Advanced Medicine
Medicine Multispecialty Center
4921 Parkview Place, Suite C, 5 Floor
314-286-2700, option 2
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Areas of Clinical Interest
Washington Univesrsity School of Medicine
Division of Geriatrics and Nutritional Science
660 South Euclid Avenue, Campus Box 8303
Dementia care, memory impairment, frailty in older adults, osteoporosis, hip fracture rehabilitation, estrogen/hormone replacement therapy, exercise in older adults, medical care for older adults in both the long-term care and out-patient settings.
Areas of Research Interest
Exercise in older adults, physical frailty, sarcopenia (age-associated muscle loss), hip fracture recovery and rehabilitation, hormone replacement therapy in women and men, nursing home clinical trials, mild cognitive impairment.
B.A.: Psychology, University of Michigan, Ann Arbor, Michigan, 1977
Medical Degree: Washington University, St. Louis, Missouri, 1981
Residency: Internal Medicine, Jewish Hospital of St. Louis, St. Louis, Missouri, 1984
Honors and Awards
Listed in Best Doctors of America, 2009-2013 (Best Doctors, Inc.)
Research Grant Awards
Combining exercise and cognitive training to improve everyday function”
Source: NIA, NIH R01 (PI Binder/McDaniel), Funding period: 7/1/09-6/31/12
Adapted acute medical rehabilitation as an intervention for late-life depression after hip fracture. Source: NIMH, NIH R34 MH083868 (PI Lenze). Funding Period: 9/1/09-8/31/11
Risk Genes for Late Life Depression After Hip Fracture. Source: NIMH, NIH R01 MH074596 (PI Lenze). Funding Period: 3/1/07-2/29/12
Journal of American Geriatrics Society
Journal of American Geriatrics Society
Journal of Gerontology: Medical Sciences
Annals of Internal Medicine
Journal of Applied Physiology
Journal of Aging and Physical Activity
American Journal of Epidemiology
Amer Journal of Physical Medicine & Rehabilitation
Calcified Tissue International
Peer Reviewed Manuscripts
Mehr DR, Binder EF, Kruse R., Zweig S C, Madsen R, D'Agostino R B How good are clinical findings at identifying pneumonia in nursing home residents? J Fam Pract (in press)
Bhasin S, He EJ, Kawakubo M, Schroeder T, Yarasheski K, Opitech GJ, Reicin A, Chen F, Lam R, Tsou JA, Castaneda-Sceppa C, Binder EF, Azen SP, Sattler FR. N-terminal propeptide of type III procollagen (P3NP) as a biomarker of anabolic response to recombinant human growth hormone and testosterone. J Clin Endocrinol Metab (in press)
Sattler FR, Casteneda-Sceppa C, Binder EF, Schoeder ET, Wang Y, Bhasin S, Kawakubo M, Sterward Y, Yarasheski KE, Ulloor J, Colletti P, Roubenoff R, Azen SP. Testosterone and growth hormone improve body composition and muscle performance in older men. J Clin Endocrinol Metab 94: 1991-2001, 2009
Schroeder ET, Castaneda-Sceppa C, Wang Y, Binder EF, Kawakubo M, Steward Y, Storer T, Roubenoff R, Bhasin S, Yarasheski KE, Sattler FR, Azen SP. Hormonal regulators of muscle and metabolism in aging (HORMA): design and conduct of a complex double masked multicenter trial. Clinical Trials 2007; 4: 560-571.
Moylan, KC. Binder, EF. Office management of falls in older adults. Amer J Med 2007 120(6): 493.e1-6
Host HH, Sinacore DR, Bohnert KL, Steger-May K, Brown MB, Binder EF. Training induced adaptations after hip fracture. Physical Therapy 2007 87(3):292-303.
Gage BF, Birman-Deych E, Radford MJ, Nilasena DS, Binder EF. Risk of Osteoporotic Fracture in Elderly Patients Taking Warfarin: Results from the National Registry of Atrial Fibrillation 2. Arch Int Med 2006 166(2):241-6.
Carr DB, Flood K, Steger-May K, Schechtman KB, Binder EF. Characteristics of frail older adult drivers. J Am Geriatr Soc 2006 54:1125-9.
Binder EF, Yarasheski KE, Steger-May K, Sinacore DR, Brown M, Schechtman KB, Holloszy JO. Effects of progressive resistance training on body composition in the frail elderly: Results of a randomized, controlled trial. J Gerontol Med Sci 2005; 60(11):1425-31.
Gravenstein S, Drinka P, Osterweil D, Schilling M, Krause P, Elliott M, Shult P, Ambrozaitis A, Kandel R, Binder E, Hammond J, McElhaney J, Flack N, Daly J, Keene O. Inhaled zanamivir versus rimantadine for the control of influenza in a highly-vaccinated long-term care population. J Am Med Dir Assoc 2005; 6: 367-374.
Kruse RL, Mehr DR, Boles KE, Lave JR, Binder EF, Madsen R, D’Agostino RB. Does hospitalization make a difference? 30-Day survival following lower respiratory infection in nursing home residents. Medical Care 2004; 42: 860-870.
Binder EF, Sinacore DR, Brown M, Steger-May, K, Schechtman K. Effects of extended outpatient rehabilitation after hip fracture: A randomized, controlled trial. JAMA 2004; 292: 837-846.
Zweig SC, Kruse RL, Binder EF, Szafara CL, Mehr DR. Impact of Do Not Resuscitate (DNR) orders on hospitalization of nursing home residents evaluated for lower respiratory infections. J Am Geriatr Soc 2004; 52: 51-58.
Villareal DT, Steger-May K, Schechtman KB, Yarasheski KE, Brown M, Sinacore DR, Binder EF. Effects of exercise training on bone mineral density in frail older women and men: a randomized, controlled trial. Age Aging 2004; 33(3):309-12.
Ehsani, AA, Spina RJ, Peterson LR, Rinder MR, Glover KL, Villareal DT, Binder EF, Holloszy JO. Attenuation of cardiovascular adaptations to exercise in frail octogenarians. J Appl Physiol 2003; 95(5):1781-8.
Villareal DT, Binder EF, Yarasheski KE, Williams DB, Brown M, Sinacore DR, Kohrt WM. Effects of exercise training added to ongoing HRT on bone mineral density in frail elderly women. J Am Geriatr Soc 2003; 51:985-990.
Pinto AB, Binder EF, Kohrt WM, Bronder DR, Williams DB. Effects of tri-monthly progestin administration on the endometrium in elderly postmenopausal women on hormone replacement: a pilot study. Am J Obstet Gynecol 2003; 189: 11-15.
Schneider JK, Eveker A, Meiner S, Binder EF. Incentives and disincentives for participating in an exercise program for individuals 78 years of age and older. J Gerontol Nurs 2003; 29: 21-31.
Binder EF, Kruse RL, Sherman AK, Madsen R, Zweig SC, Mehr DR. Predictors of short-term functional decline of nursing home residents with lower respiratory tract infection (LRI). J Gerontol Med Sci 2003 58A: M60-M67.
Binder EF., Schechtman, KB, Ehsani AA, Steger-May, K, Sinacore DR, Brown M, Yarasheski KE, Holloszy JO. Effects of exercise training on measures of frailty in community-dwelling elderly adults: Results of a randomized, controlled trial. J Am Geriatr Soc 2002: 50:1921-1928.
Barry CR, Brown K, Esker D, Denning MD, Kruse RL, Binder EF. Nursing assessment of ill nursing home residents. J Gerontol Nurs 2002; May;28(5):4-7
Mehr DR, Binder EF, Kruse RL, Zweig SC, Madsen R, Popejoy L, D'Agostino RB. Predicting mortality in nursing home residents with lower respiratory tract infection: The Missouri LRI Study. JAMA 2001; Nov 21;286(19):2427-36
Mehr DR, Binder EF, Kruse RL, Zweig SC, Madsen RW, D'Agostino RB. Clinical findings associated with radiographic pneumonia in nursing home residents. J Fam Pract 2001; Nov;50(11):931-7
Binder EF, Miller JP, Ball LJ. Development of a test of physical performance for the nursing home setting. Gerontologist 2001; Oct;41(5):671-9
Villareal DT, Binder EF, Williams DB, Schechtman KB, Yarasheski KE, Kohrt WM. Bone mineral density response to estrogen replacement in frail elderly women: a randomized controlled trial. JAMA 2001; Aug 15;286(7):815-20
Evans EM, Van Pelt RE, Binder EF, Williams DB, Ehsani AA, Kohrt WM. Effects of HRT and exercise training on insulin action, glucose tolerance, and body composition in older women. J Appl Physiol 2001; Jun;90(6):2033-40
Binder EF, Williams DB, Schechtman KB, Jeffe DB, Kohrt WM. Effects of hormone replacement therapy on serum lipids in elderly women. a randomized, placebo-controlled trial. Ann Intern Med 2001; May 1;134(9 Pt 1):754-60
Binder EF, Schechtman KB, Birge SJ, Williams DB, Kohrt WM. Effects of hormone replacement therapy on cognitive performance in elderly women.
Maturitas 2001; Apr 20;38(2):137-46
Jeffe DB, Binder EF, Williams DB, Kohrt WM. Frail older women's participation in a trial of hormone replacement therapy: perceived benefits and concerns. Menopause 2001; Summer;8(2):127-34
Binder EF, Kohrt WM. Relationships between body composition and bone mineral content and density in older women and men. Clin Exercise Physiol 2000; 2(2):84-91
Brown M, Sinacore DR, Binder EF, Kohrt WM. Physical and performance measures for the identification of frailty. J Gerontol Med Sci 2000; 55A(6):M350-M355
For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Ellen F. Binder