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David B. Wilson, MD, PhD

Current Position
Associate Professor, Pediatrics
Division of Pediatric Hematology and Oncology
Associate Professor, Molecular Biology and Pharmacology

Specialty Areas
Pediatric Hematology
Pediatric Kidney Transplant
Pediatric Oncology

Patients Seen At
Medical Building Three
Barnes-Jewish West County Hospital
1020 N. Mason Road, Suite 110
Creve Coeur, MO  63141
Fax:   314-454-2780
View Campus Map   View Driving Directions

St Louis Children's Hospital
One Children's Place, 9th Floor
St. Louis, MO  63110
Fax:   314-454-2780
View Driving Directions

Mailing Address
Washington University School of Medicine
660 S. Euclid Avenue, Campus Box 8116
St. Louis, MO  63110

Areas of Clinical Interest
Birth defects, acute leukemia, in vitro development, Hodgkin's disease, renal transplantation, kindey transplantation, hormonal regulation, pediatric yolk sac tumors, cardiac specific troponin, molecular biology, pharmacology, diseases of the fetus, diseases of the infant,  bone marrow failure and coagulation disorders

Areas of Research Interest
The laboratory study of the regulation of normal and pathological development.

Board Certification
Pediatrics -- Certified
Pediatric Hematology -- Certified
Pediatric Oncology -- Certified

Medical Education
B.A.: Kalamazoo College, Kalamazoo, Michigan, 1980
Ph.D: Washington University School of Medicine, St. Louis, Missouri, 1986
Medical Degree: Washington University School of Medicine, St. Louis, Missouri, 1986
Fellowship: Pediatrics, Hematology / Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, 1989
Fellowship: Medicine Hematology / Oncology, The Children's Hospital, Boston, Massachusetts, 1990
Fellowship: Pediatrics, Harvard Medical School, Boston, Massachusetts, 1990
Hospital Affiliations
Barnes-Jewish Hospital
St. Louis Children's Hospital

Honors and Awards
Listed in Best Doctors in America, 2003-2013 (Best Doctors, Inc.)

Selected or Recent Journal Articles
Schillebeeckx M, Schrade A, Löbs AK, Pihlajoki M, Wilson DB, Mitra RD. Laser capture microdissection-reduced representation bisulfite sequencing (LCM-RRBS) maps changes in DNA methylation associated with gonadectomy-induced adrenocortical neoplasia in the mouse. Nucleic Acids Res. 2013 Jun 1;41(11):e116. Epub 2013 Apr 15.

Pihlajoki M, Gretzinger E, Cochran R, Kyrönlahti A, Schrade A, Hiller T, Sullivan L, Shoykhet M, Schoeller EL, Brooks MD, Heikinheimo M, Wilson DB. Conditional mutagenesis of Gata6 in SF1-positive cells causes gonadal-like differentiation in the adrenal cortex of mice. Endocrinology. 2013 May;154(5):1754-67.

Krachulec J, Vetter M, Schrade A, Löbs AK, Bielinska M, Cochran R, Kyrönlahti A, Pihlajoki M, Parviainen H, Jay PY, Heikinheimo M, Wilson DB. GATA4 is a critical regulator of gonadectomy-induced adrenocortical tumorigenesis in mice. Endocrinology. 2012 Jun;153(6):2599-611.

Zou J, Majerus PW, Wilson DB, Schrade A, Chang SC, Wilson MP. The role of myotubularin-related phosphatases in the control of autophagy and programmed cell death. Adv Biol Regul. 2012 Jan;52(1):282-9. Review. No abstract available.

Kyrönlahti A, Vetter M, Euler R, Bielinska M, Jay PY, Anttonen M, Heikinheimo M, Wilson DB. GATA4 deficiency impairs ovarian function in adult mice. Biol Reprod. 2011 May;84(5):1033-44.

Kyrönlahti A, Euler R, Bielinska M, Schoeller EL, Moley KH, Toppari J, Heikinheimo M, Wilson DB. GATA4 regulates Sertoli cell function and fertility in adult male mice. Mol Cell Endocrinol. 2011 Feb 10;333(1):85-95.

Bessler M, Wilson DB, Mason PJ. Dyskeratosis congenita. FEBS Lett. 2010 Sep 10;584(17):3831-8.

McDonald S, Wilson DB, Pumbo E, Kulkarni S, Mason PJ, Else T, Bessler M, Ferkol T, Shenoy S. Acquired monosomy 7 myelodysplastic syndrome in a child with clinical features suggestive of dyskeratosis congenita and IMAGe association. Pediatr Blood Cancer. 2010 Jan;54(1):154-7.

Majerus PW, Wilson DB, Zhang C, Nicholas PJ, Wilson MP. Expression of inositol 1,3,4-trisphosphate 5/6-kinase (ITPK1) and its role in neural tube defects. Adv Enzyme Regul. 2010;50(1):365-72.

Schuettpelz LG, McDonald S, Whitesell K, Desruisseau DM, Grange DK, Gurnett CA, Wilson DB. Pilocytic astrocytoma in a child with Noonan syndrome. Pediatr Blood Cancer. 2009 Dec;53(6):1147-9.

Kanter J, Wilson DB, Strasberg S. Downsizing to resectability of a large solid and cystic papillary tumor of the pancreas by single-agent chemotherapy. J Pediatr Surg. 2009 Oct;44(10):e23-5.

Wilson MP, Hugge C, Bielinska M, Nicholas P, Majerus PW, Wilson DB. Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9831-5.

Bielinska M, Parviainen H, Kiiveri S, Heikinheimo M, Wilson DB. Review paper: origin and molecular pathology of adrenocortical neoplasms. Vet Pathol. 2009 Mar;46(2):194-210.

Du HY, Pumbo E, Ivanovich J, An P, Maziarz RT, Reiss UM, Chirnomas D, Shimamura A, Vlachos A, Lipton JM, Goyal RK, Goldman F, Wilson DB, Mason PJ, Bessler M. TERC and TERT gene mutations in patients with bone marrow failure and the significance of telomere length measurements. Blood. 2009 Jan 8;113(2):309-16.

Wagner S, Kiupel M, Peterson RA 2nd, Heikinheimo M, Wilson DB. Cytochrome b5 expression in gonadectomy-induced adrenocortical neoplasms of the domestic ferret (Mustela putorius furo). Vet Pathol. 2008 Jul;45(4):439-42

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. David B. Wilson.

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Copyright 2015 Washington University School of Medicine