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Neurology / Pediatric

Anne Maureen Connolly, MD

Current Position
Professor, Neurology
Division of Pediatric Neurology
Professor, Pediatrics

Specialty Areas
Pediatric Neurology
Nerve Disorders
Muscle Disorders
Muscular Dystrophy
Myasthenia Gravis
Neuromuscular Disease
ALS - Lou Gehrig's Disease

Patients Seen At
Neuroscience Center
Center for Advanced Medicine
4921 Parkview Place, Suite C, 6 Fl
St. Louis, MO  63110
Fax:   314-362-3752
View Floor Map  View Campus Map   View Driving Directions

St. Louis Children's Hospital
One Children's Place, Suite D
St. Louis, MO  63110
Fax:   314-454-2523
View Driving Directions

Mailing Address
Washington Unviersity School of Medicine
Department of Neurology
660 South Euclid Ave., Campus Box 8111
St. Louis, MO  63110

Areas of Clinical Interest
Childhood chronic demyelinating polyneuropathy, Duchenne muscular dystrophy, congenital muscular dystrophy syndromes, brachial plexus injury, myotonia congenita, childhood opsoclonus-myoclonus, spiral muscularatrophy, childhood myasthenia gravis, myasthenic syndrome, childhood neuropathy, childhood electromyography, neuromuscular disease, electromyography, electrodiagnostic studies,, nerve disorders.

Board Certification
EMG -- Certified
Pediatrics -- Certified
Pediatric Neurology -- Certified

Medical Education
B.S.: Saint Mary's College, Notre Dame, Indiana, 1980
Medical Degree: Indiana University, Indianapolis, Indiana, 1984
Residency: Pediatrics, St. Louis Children's Hospital, St. Louis, Missouri, 1987
Residency: Neurology, Barnes Hospital/Washington University School of Medicine, St. Louis, Missouri, 1988
Fellowship: Child Neurology, St. Louis Children's Hospital, St. Louis, Missouri, 1990
Hospital Affiliations
Barnes-Jewish Hospital
St. Louis Children's Hospital

Honors and Awards
Listed in Best Doctors in America, 2005-2013 (Best Doctors, Inc.)

Editorial Responsibilities

Cancer Research Campaign, London, UK
Journal of Child Neurology
Journal of the International League Against Epilepsy on the Subject of Landau-Kleffner Syndrome

Selected or Recent Journal Articles
Bibee KP, Cheng YJ, Ching JK, Marsh JN, Li AJ, Keeling RM, Connolly AM, Golumbek PT, Myerson JW, Hu G, Chen J, Shannon WD, Lanza GM, Weihl CC, Wickline SA. Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac function. FASEB J. 2014 Feb 5. [Epub ahead of print]

Allen HD, Flanigan KM, Thrush PT, Dvorchik I, Yin H, Canter C, Connolly AM, Parrish M, McDonald CM, Braunlin E, Colan SD, Day J, Darras B, Mendell JR. A randomized, double-blind trial of lisinopril and losartan for the treatment of cardiomyopathy in duchenne muscular dystrophy. PLoS Curr. 2013 Dec 12;5. pii:

Connolly AM, Florence JM, Cradock MM, Malkus EC, Schierbecker JR, Siener CA, Wulf CO, Anand P, Golumbek PT, Zaidman CM, Philip Miller J, Lowes LP, Alfano LN, Viollet-Callendret L, Flanigan KM, Mendell JR, McDonald CM, Goude E, Johnson L, Nicorici A, Karachunski PI, Day JW, Dalton JC, Farber JM, Buser KK, Darras BT, Kang PB, Riley SO, Shriber E, Parad R, Bushby K, Eagle M; MDA DMD Clinical Research Network. Motor and cognitive assessment of infants and young boys with Duchenne Muscular Dystrophy: results from the Muscular Dystrophy Association DMD Clinical Research Network. Neuromuscul Disord. 2013 Jul;23(7):529-39.

Connolly AM, Kim HJ, Bridwell KH. Corticosteroids can reduce the severity of scoliosis in Duchenne muscular dystrophy. J Bone Joint Surg Am. 2013 Jun 19;95(12):e86.

Escolar DM, Zimmerman A, Bertorini T, Clemens PR, Connolly AM, Mesa L, Gorni K, Kornberg A, Kolski H, Kuntz N, Nevo Y, Tesi-Rocha C, Nagaraju K, Rayavarapu S, Hache LP, Mayhew JE, Florence J, Hu F, Arrieta A, Henricson E, Leshner RT, Mah JK. Pentoxifylline as a rescue treatment for DMD: a randomized double-blind clinical trial. Neurology. 2012 Mar 20;78(12):904-13.

Escolar DM, Hache LP, Clemens PR, Cnaan A, McDonald CM, Viswanathan V, Kornberg AJ, Bertorini TE, Nevo Y, Lotze T, Pestronk A, Ryan MM, Monasterio E, Day JW, Zimmerman A, Arrieta A, Henricson E, Mayhew J, Florence J, Hu F, Connolly AM. Randomized, blinded trial of weekend vs daily prednisone in Duchenne muscular dystrophy. Neurology. 2011 Aug 2;77(5):444-52.

Spurney CF, Rocha CT, Henricson E, Florence J, Mayhew J, Gorni K, Pasquali L, Pestronk A, Martin GR, Hu F, Nie L, Connolly AM, Escolar DM; Cooperative International Neuromuscular Research Group Investigators. CINRG pilot trial of coenzyme Q10 in steroid-treated Duchenne muscular dystrophy. Muscle Nerve. 2011 Aug;44(2):174-8.

Merrill LJ, Gurnett CA, Connolly AM, Pestronk A, Dobbs MB. Skeletal muscle abnormalities and genetic factors related to vertical talus. Clin Orthop Relat Res. 2011 Apr;469(4):1167-74.

Zaidman CM, Connolly AM, Malkus EC, Florence JM, Pestronk A. Quantitative ultrasound using backscatter analysis in Duchenne and Becker muscular dystrophy. Neuromuscul Disord. 2010 Dec;20(12):805-9.

Gurnett CA, Desruisseau DM, McCall K, Choi R, Meyer ZI, Talerico M, Miller SE, Ju JS, Pestronk A, Connolly AM, Druley TE, Weihl CC, Dobbs MB. Myosin binding protein C1: a novel gene for autosomal dominant distal arthrogryposis type 1. Hum Mol Genet. 2010 Apr 1;19(7):1165-73.

Gurnett, C.A., Boehm, S. Connolly, AM, Reimschisel, T. Dobbs, MB. Impact of congenital talipes equinovarus etiology on treatment outcomes. Dev Med Child Neurol; 2008; 50:7; 498-502.

Wallace KD, Marsh JN, Baldwin SL, Connolly AM, Keeling R, Lanza GM, Wickline SA, Hughes MS. Sensitive ultrasonic delineation of steroid treatment in living dystrophic mice with energy-based and entropy-based radio frequency signal processing. IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Nov;54(11):2291-9.

Golumbek PT, Keeling RM, Connolly AM. RAG2 gene knockout in mice causes fatigue. Muscle Nerve. 2007 Oct;36(4):471-6.

Hughes MS, Marsh JN, Wallace KD, Donahue TA, Connolly AM, Lanza GM, Wickline SA. Sensitive ultrasonic detection of dystrophic skeletal muscle in patients with duchenne muscular dystrophy using an entropy-based signal receiver. Ultrasound Med Biol. 2007 Aug;33(8):1236-43. Epub 2007 Apr 30.

Golumbek PT, Keeling RM, Connolly AM. Strength and corticosteroid responsiveness of mdx mice is unchanged by RAG2 gene knockout. Neuromuscul Disord. 2007 May;17(5):376-84. Epub 2007 Apr 23.

Keeling RM, Golumbek PT, Streif EM, Connolly AM. Weekly oral prednisolone improves survival and strength in male mdx mice. Muscle Nerve. 2007 Jan;35(1):43-8.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Anne Maureen Connolly.

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Copyright 2015 Washington University School of Medicine