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Neurology / Adult

Glenn Lopate, MD

Current Position
Associate Professor, Neurology
Division of Adult Neurology and Neuromuscular Disease

Specialty Areas
Neurology - Adult
ALS - Lou Gehrig's Disease
Myasthenia Gravis
Nerve Disorders
Muscle Disorders
Neuromuscular Disease
Muscular Dystrophy

Patients Seen At
Neuroscience Center
Center for Advanced Medicine
4921 Parkview Place, C, 6
St. Louis, MO  63110
Fax:   314-362-3752
View Floor Map  View Campus Map   View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Neurology
660 South Euclid Ave., Campus Box 8111
St. Louis, MO  63110

Areas of Clinical Interest
Neuromuscular diseases, electromyography, post-paralysis paralysis (PPP) syndrome, motor neuropathy syndromes, polyneuropathy syndromes, autoimmune myasthenia gravis, chronic immune demyelinating neuropathies, immune neuropathies, muscular dystrophies, immune myopathies, ALS-Lou Gehrig’s disease

Board Certification
Electrodiagnostic Medicine -- Certified
Neurology -- Certified

Medical Education
B.S.: Zoology, Colorado State University, Fort Collins, Colorado, 1983
Medical Degree: Ohio State University College of Medicine, Columbus, Ohio, 1987
Residency: Neurology, Washington University School of Medicine, St. Louis, Missouri, 1991
Fellowship: Neuromuscular Disease, Washington University School of Medicine, St. Louis, Missouri, 1994
Hospital Affiliations
Barnes-Jewish Hospital
St. Louis Children's Hospital
St. Louis Connect Care

Editorial Responsibilities

EMedicine Neurology Textbook, Managing Editor
Muscle & Nerve, Ad Hoc Reviewer

Invited Publications

Pestronk A, Lopate G. Polyneuropathies and antibodies to nerve components. In: Peripheral Neuropathy. Dyck PJ and Thomas PK, ed., Elsevier Saunders, Philadelphia PA, 2005; 2177-2196

Lopate G, Pestronk A. Chronic immune demyelinating neuropathies. Sem Neurol 1994; 14:131-136

Lopate G, Pestronk A. The myasthenic neuromuscular junction. Handbook of Myasthenia Gravis and Myasthenic Syndromes. Lisak RP, ed., Marcel Dekker, NY, 1994; 225-238

Lopate G, Pestronk A. Autoimmune myasthenia gravis. Hosp Prac 1993; 28:109-122

Peer Reviewed Manuscripts

Lopate G, Baloh RH, Al-Lozi MT, Miller TM, Filho JAF, Ni O, Leston A, Florence J, Schierbecker J, Allred P. Familial ALS with extreme phenotypic variability due to the I113T SOD1 mutation. Amyotroph Lateral Scler (in press).

Bello-Haas VD., Florence JM, Kloos AD, Scheirbecker J, Lopate G, Hayes SM, Pioro EP, Mitsumoto H. A randomized controlled trial of resistance exercise in individuals with ALS. Neurology 2007;68:2003-7.

Strom RG, Derdeyn CP, Moran CJ, Cross DT, Esper GJ, Mazumdar A, Al-Lozi M, Lopate G, Pestronk A. Frequency of spinal arteriovenous malformations in patients with unexplained myelopathy. Neurology 2006; 66:928-31

Weihl CC, Lopate G. Motor neuron disease associated with copper deficiency. Muscle Nerve 2006 Aug 23; [Epub ahead of print] PMID: 16929546 [PubMed - as supplied by publisher]

Lopate G, Pestronk A, Al-Lozi M, Lynch T, Florence J, Miller T, Levine T, Rampy T, Beson B, Ramneantu I. Peripheral neuropathy in an outpatient cohort of patients with Sjogren's syndrome. Muscle Nerve 2006; 33:672-6

Pestronk A, Kos K, Lopate G, Al-Lozi MT. Brachio-cervical inflammatory myopathies: clinical, immune, and myopathologic features. Arth Rheum 2006; 54:1687-96

Levine T, Pestronk A, Florence J, Al-Lozi MT, Lopate G, Miller T, Ramneantu I, Waheed W, Stambuk M, Stone MJ, Choksi R. Peripheral neuropathies in Waldenstrom's macroglobulinaemia. J Neurol Neurosurg Psych 2006; 77:224-228

Lopate G, Pestronk A, Al-Lozi M. Treatment of chronic inflammatory demyelinating polyneuropathy with high-dose intermittent intravenous methylprednisolone. Arch Neurol 2005; 62:249-54

Lopate G, Pestronk A, Evans S, Li L, Clifford D. Anti-sulfatide antibodies in HIV-infected individuals with sensory neuropathy. Neurology 2005; 64:1632-1634

Pestronk A, Florence J, Levine T, Al-Lozi MT, Lopate G, Miller T, Ramneantu I, Waheed W, Stambuk M. Sensory exam with a quantitative tuning fork: rapid, sensitive and predictive of SNAP amplitude. Neurology 2004; 62:461-464

Racette BA, Lopate G, Good L, Sagitto S, Perlmutter JS. Ptosis as a remote effect of therapeutic botulinum toxin B injection. Neurology 2002; 59:1445-47

Miller T, Al-Lozi MT, Lopate G, Pestronk A. Myopathy with antibodies to the signal recognition particle: Clinical and pathological features. J Neurol, Neurosurg Psychiatry 2002; 73:420-428

Lopate G, Choksi R, Pestronk A. Severe sensory ataxia and demyelinating polyneuropathy with IgM anti-GM2 and GalNAc-GD1a antibodies. Muscle Nerve 2002; 25:828-836

Kovach MJ, Waggoner B, Leal SM, Gelber D, Khardori R, Levenstien MA, Shanks CA, Gregg G, Al-Lozi MT, Miller T, Rakowicz W, Lopate G, Florence J, Glosser G, Simmons Z, Morris JC, Whyte MP, Pestronk A, Kimonis VE. Clinical delineation and localization to chromosome 9p13.3-p12 of a unique dominant disorder in four families: Hereditary inclusion body myopathy, Paget disease of bone and frontotemporal dementia. Molec Gene Metab 2001; 74:458-475

Lopate G, Kornberg AJ, Yue J, Choksi R, Pestronk A. Anti-myellin associated glycoprotein antibodies: Variability in patterns of IgM binding to peripheral nerve. J Neurol Sci 2001;188:67-72

Mozaffer T, Lopate G, Pestronk A. Clinical correlates of granulomas in muscle. J Neurol 1998; 245:519-524

Pestronk A, Choksi R, Yee W-C, Kornberg AJ, Lopate G, Trotter J. Serum antibodies to heparan sulfate glycosamingoglycan in Guillain-Barre and other demyelinating neuropathies. J Neuroimmunol 1998: 91:204-209

Lopate G, Pestronk A, Yee W-C. N-lines in a myopathy with myosin loss. Muscle Nerve 1998; 21:1216-1219

Lopate G, Kornberg AJ, Yue J, Choski R, Pestronk A. IgM anti-sulfatide autoantibodies: Patterns of binding to cerebellum, dorsal root ganglia and peripheral nerve. J Neurol Sci 1997; 151:189-193

Pestronk A, Choksi R, Blume G, Lopate G. Multifocal motor neuropathy: Serum IgM binding to GM1 anglioside-containing lipid mixture but not to GM1 alone. Neurology 1997; 48:1104-1106

Lopate G, Parks BJ, Goldstein JM, Yee W-C, Friesenhahn GM, Pestronk A. Polyneuropathies associated with high-titer anti-sulfatide antibodies: Characteristics of patients with and without serum M-proteins. J Neurol Neurosurg Psychiatry 1997; 62:581-585

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Glenn Lopate

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Copyright 2014 Washington University School of Medicine