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David A. Hunstad, MD

Current Position
Assistant Professor, Pediatrics
Division of Infectious Diseases
Assistant Professor, Molecular Microbiology

Specialty Areas
Infectious Diseases
Pediatric Diagnostics
Pediatric Infectious Disease

Patients Seen At
St. Louis Children's Hospital
Diagnostic Center
One Children's Place, Suite C, 2nd Floor
St. Louis, MO  63110
Fax:   314-454-2524
View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Pediatrics, Division of Infectious Diseases
CB 8116, 660. S. Euclid Ave
St. Louis , MO  63110

Areas of Clinical Interest
Pediatric infectious diseases, diagnostic medicine,  community acquired MRSA

Areas of Research Interest
Dr. Hunstad's research interests are focused on the interaction of gram-negative bacteria and their hosts,  Related projects in the laboratory are aimed at determining how bacteria assemble outer membrane protein virulence factors on their surfaces. The goal of these studies is to develop new targets useful in the prevention and treatment of gram-negative bacterial infections of the urinary tract, gastrointestinal tract, and central nervous system.

Hunstad Lab Web Page

Board Certification
Pediatric Infectious Diseases -- Certified
Pediatrics -- Certified

Medical Education
B.A.: Carleton College, Northfield, Minnesota, 1991
Medical Degree: Washington University School of Medicine, St. Louis, MO, 1995
Residency, Pediatrics: St. Louis Children's Hospital, St. Louis, MO, 1998
Chief Resident, Pediatrics: St. Louis Children's Hospital, St Louis, MO, 1999
Fellowship: Pediatric Infectious Diseases, Washington University School of Medicine, St. Louis MO 63110, 2003
Hospital Affiliations
St. Louis Children's Hospital

Selected or Recent Journal Articles
Heble DE Jr, McPherson C, Nelson MP, Hunstad DA. Vancomycin Trough Concentrations in Overweight or Obese Pediatric Patients. Pharmacotherapy. 2013 Jun 24.

Fritz SA, Tiemann KM, Hogan PG, Epplin EK, Rodriguez M, Al-Zubeidi DN, Bubeck Wardenburg J, Hunstad DA. A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection. Clin Infect Dis. 2013 Jun;56(11):1554-61.

Lau ME, Loughman JA, Hunstad DA. YbcL of uropathogenic Escherichia coli suppresses transepithelial neutrophil migration. Infect Immun. 2012 Dec;80(12):4123-32.

McPherson C, Warner B, Hunstad DA, Elward A, Acosta EP. Oseltamivir dosing in premature infants. J Infect Dis. 2012 Sep 15;206(6):847-50.

Loughman JA, Hunstad DA. Induction of indoleamine 2,3-dioxygenase by uropathogenic bacteria attenuates innate responses to epithelial infection. J Infect Dis. 2012 Jun 15;205(12):1830-9.

Lin LY, Tiemann KM, Li Y, Pinkner JS, Walker JN, Hultgren SJ, Hunstad DA, Wooley KL. Synthetic polymer nanoparticles conjugated with FimH(A) from E. coli pili to emulate the bacterial mode of epithelial internalization. J Am Chem Soc. 2012 Mar 7;134(9):3938-41.

Justice SS, Hunstad DA. UPEC hemolysin: more than just for making holes. Cell Host Microbe. 2012 Jan 19;11(1):4-5.

Loughman JA, Hunstad DA. Attenuation of human neutrophil migration and function by uropathogenic bacteria. Microbes Infect. 2011 Jun;13(6):555-65.

Horvath DJ Jr, Li B, Casper T, Partida-Sanchez S, Hunstad DA, Hultgren SJ, Justice SS. Morphological plasticity promotes resistance to phagocyte killing of uropathogenic Escherichia coli. Microbes Infect. 2011 May;13(5):426-37.

Zhang B, Watts KM, Hodge D, Kemp LM, Hunstad DA, Hicks LM, Odom AR. A second target of the antimalarial and antibacterial agent fosmidomycin revealed by cellular metabolic profiling. Biochemistry. 2011 May 3;50(17):3570-7.

Fritz SA, Krauss MJ, Epplin EK, Burnham CA, Garbutt J, Dunne WM, Hunstad DA, Storch GA. The natural history of contemporary Staphylococcus aureus nasal colonization in community children. Pediatr Infect Dis J. 2011 Apr;30(4):349-51.

Li Y, Hindi K, Watts KM, Taylor JB, Zhang K, Li Z, Hunstad DA, Cannon CL, Youngs WJ, Wooley KL. Shell crosslinked nanoparticles carrying silver antimicrobials as therapeutics.  Chem Commun (Camb). 2010 Jan 7;46(1):121-3.

Hunstad DA, Justice SS. Intracellular lifestyles and immune evasion strategies of uropathogenic Escherichia coli. Annu Rev Microbiol. 2010;64:203-21.

Nicholson TF, Watts KM, Hunstad DA. OmpA of uropathogenic Escherichia coli promotes postinvasion pathogenesis of cystitis. Infect Immun. 2009 Dec;77(12):5245-51.

Orscheln RC, Hunstad DA, Fritz SA, Loughman JA, Mitchell K, Storch EK, Gaudreault M, Sellenriek PL, Armstrong JR, Mardis ER, Storch GA. Contribution of genetically restricted, methicillin-susceptible strains to the ongoing epidemic of community-acquired Staphylococcus aureus infections. Clin Infect Dis. 2009 Aug 15;49(4):536-42.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. David A. Hunstad.

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Copyright 2015 Washington University School of Medicine