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Pediatrics

Mark D. Levin, MD

Current Position
Instructor, Pediatrics
Division of Pediatric Cardiology


Specialty Areas
Pediatric Cardiology
Arrhythmia - Pediatric

Patients Seen At
St. Louis Children's Hospital
One Children's Place, Suite D, 2nd Floor
St. Louis, MO  63110
314-454-6095
Fax:   314-454-2561
View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Pediatrics, Cardiology
CB 8208, 660 S. Euclid Ave
St. Louis, MO  63110

Areas of Clinical Interest
pediatric arrhythmia, heart rhythm disturbances in children and adults with congenital heart disease, inherited sudden death syndromes, heart conditions in children, congenital heart disease, cardiac electrophysiology, pediatric EP

Areas of Research Interest
Dr. Levin uses engineered animal models to delineate mechanisms of arrhythmias and conduction system disease, with special focus on mechanisms of triggered activity and atrial arrhythmias.

Board Certification
Pediatrics -- Certified
Pediatric Cardiology -- Certified

Medical Education
B.A.: Columbia College, Columbia University, New York, , 1990
Medical Degree: Boston University School of Medicine, Boston MA, 1998
Residency: Pediatrics, Babies and Children's Hospital of Philadelphia, PA, 2001
Fellowship: Cardiology, University of Philadelphia Medical School, Philadelphia, PA, 2004
Fellowship (Research): Cardiovascular Institute, University of Pennsylvania, Philadelphia, PA, 2009
Advanced Training: Non-invasive Clinical Cardiac Electrophysiology, Children's Hospital of Philadelphia, PA, 2009
Hospital Affiliations
St. Louis Children's Hospital, St. Louis MO

Selected or Recent Journal Articles
Mark D. Levin, Paul Stephens Jr., Ronn E. Tanel, Victoria L. Vetter, Larry A. Rhodes, “Ventricular Tachycardia in Infants with Structurally Normal Hearts: A Benign Disorder,” Cardiology in the Young, 20(6): 641-7, 2010

Hawkins BJ, Levin MD, Petrenko, NB, Patel VV, Davis C, Thompson CB, Madesh M. A complex II regulated form of mitochondrial dysfunction in metabolically exhausted cells. Journal of Biological Chemistry, 285: 26494-26505, 2010.

Hawkins BJ, Levin MD, Doonan PJ, Petrenko NB, Davis CW, Patel VV, Madesh M. Mitochondrial complex II prevents hypoxic but not calcium- and proapoptotic Bcl-2 protein-induced mitochondrial membrane potential loss. J Biol Chem. 2010 Aug 20;285(34):26494-505.

Dairong Wang, Vickas V. Patel, Rong Zhou, Mark D. Levin, Ehre Gao, Victor A. Ferrari, Min Min Lu, Junwang Xu, Hualei Zhang, Yiqun Hui, Yan Cheng, Nataliya Petrenko, Ying Yu and Garret A. FitzGerald. Cardiomyocyte cyclooxygenase-2 influences cardiac rhythm and function” PNAS, 106: 7548-7552, 2009.

M.D. Levin, M.M. Lu, N.B. Petrenko, B.J. Hawkins, D. Lang, J.T. Jacobson, C.F. Spurney, F. Liu, C.B. Brown, L. Huang, F. Beermann, M. Muniswamy, J.A. Epstein, V.V. Patel, “A novel population of melanocyte-like cells in the heart and pulmonary veins are a source of triggers for atrial arrhythmogenesis”, Journal of Clinical Investigation, 119:3420-3436, 2009.

Jifen Li, Mark Levin, Yanming Xiong, Nataliya Petrenko, Vickas V. Patel, and Glenn L. Radice“N-cadherin haploinsufficiency affects cardiac gap junctions and arrhythmic susceptibility” Journal of Molecular and Cellular Cardiology, 44: 597-606, 2008.

Fang Liu, Mark D. Levin, Nataliya B. Petrenko, Min M. Lu, Tao Wang, Andrea L. Stout, Jonathan A. Epstein, and Vickas V. Patel, “Histone-deacetylase Inhibition Reverses Atrial Fibrillation Inducibility and Atrial Remodeling Independent of Angiotensin in Cardiac Hypertrophy” Journal of Molecular and Cellular Cardiology, 45: 715-723, 2008.

Gillespie MJ, Kaltman JR, Kaltman S, Levin MD, Stephens P, Petit CJ, Schachtner S, Rome JJ. Preferred Management Strategies for Uncomplicated Atrial Septal Defects: A Physician Survery. Journal of the American College of Cardiology, 51:B70-B70m, 2008.

Radice GL, Li JF, Levin MD, Xiong YM, Petrenko N, Patel VV. Intercellular Adhesion and Cardiac Arrhythmia: What's the Connection? Elsevier Gmbh, Urban & Fischer Verlag:434-435, 2008.

Mark D. Levin, Paul Stephens Jr., Ronn E. Tanel, Victoria L. Vetter, Larry A. Rhodes,“Ventricular Tachycardia in Infants with Structurally Normal Hearts: A Benign Disorder,” Cardiology in the Young, accepted, February 2010.* M.D. Levin, M.F. Kubke, M. Schneider, R. Wenthold, and C.E. Carr “AMPA-Selective Glutamate Receptors in the Auditory Brainstem of the Barn Owl,” Journal of Comparative Neurology, 378: 239-253, 1997.

M.D. Levin, M.F. Kubke, M. Schneider, R. Wenthold, and C.E. Carr “AMPA-Selective Glutamate Receptors in the Auditory Brainstem of the Barn Owl,” Journal of Comparative Neurology, 378: 239-253, 1997.


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