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Pediatrics

Yumirle Padron Turmelle, MD

Current Position
Assistant Professor, Pediatrics
Division of Gastroenterology and Nutrition
Medical Director, Liver Care Center, St. Louis Children's Hospital


Specialty Areas
Pediatric Gastroenterology
Pediatric Liver Transplantation
Hepatology/Liver Disease

Patients Seen At
St. Louis Children's Hospital
One Children's Place, Suite C, 2nd Floor
St Louis , MO  63110
314-454-6173
Fax:   314-454-2412
View Driving Directions

Additional Languages Spoken
Spanish

Mailing Address
Washington University School of Medicine
Department of Pediatrics
CB 8116
660 South Euclid Ave
St. Louis , MO  63110

Areas of Clinical Interest
Pediatric liver and biliary disease, liver transplant, liver pancreas transplant, hepatic adenomatosis, 

Areas of Research Interest
Interested in analyzing molecular signals that regulate liver regeneration in a surgical murine animal model; the molecular genetic analyses of extrahepatic biliary atresia;  the prevalence and utility of specific polymorphisms in genes known or suspected to influence hepatic fibrogenesis in patients with neonatal cholestasis for predicting likelihood of progression to ESLD and liver transplantation.

Board Certification
Pediatric Gastroenterology -- Certified
Pediatrics -- Certified

Medical Education
B.A. : University of Miami, Miami, FL, 1996
Medical School: University of Florida College of Medicine, Gainesville, FL, 2000
Residency: Pediatrics, Jackson Memorial Hospital, University of Miami, Miami, Fl, 2003
Fellowship: Pediatric Gastroenterology and Nutrition, Washington University School of Medicine, St. Louis MO, 2006
Fellowship: Advanced Hepatology, Washington University School of Medicine, St. Louis MO, 2007
M.S.: Public Health, St Louis University School of Public Health, St Louis MO, 2009
Hospital Affiliations
St. Louis Children's Hospital, St. Louis MO

Honors and Awards
Listed in Best Doctors in America, 2011-2013 (Best Doctors, Inc.)

Selected or Recent Journal Articles
Siebrasse EA, Bauer I, Holtz LR, Le BM, Lassa-Claxton S, Canter C, Hmiel P, Shenoy S, Sweet S, Turmelle Y, Shepherd R, Wang D. Human polyomaviruses in children undergoing transplantation, United States, 2008-2010. Emerg Infect Dis. 2012 Oct;18(10):1676-9.

Palermo JJ, Joerger S, Turmelle Y, Putnam P, Garbutt J. Neonatal cholestasis: opportunities to increase early detection. Acad Pediatr. 2012 Jul-Aug;12(4):283-7.

Conzen KD, Lowell JA, Chapman WC, Darcy M, Duncan JR, Nadler M, Turmelle YP, Shepherd RW, Anderson CD. Management of excluded bile ducts in paediatric orthotopic liver transplant recipients of technical variant allografts. HPB (Oxford). 2011 Dec;13(12):893-8.

Earl TM, Wellen JR, Anderson CD, Nadler M, Doyle MM, Shenoy SS, Chapman WC, Turmelle Y, Weymann A, Lowell JA. Small bowel obstruction after pediatric liver transplantation: the unusual is the usual. J Am Coll Surg. 2011 Jan;212(1):62-7.

Anderson CD, Turmelle YP, Darcy M, Shepherd RW, Weymann A, Nadler M, Guelker S, Chapman WC, Lowell JA. Biliary strictures in pediatric liver transplant recipients - early diagnosis and treatment results in excellent graft outcomes. Pediatr Transplant. 2010 May;14(3):358-63.

Wellen JR, Anderson CD, Doyle M, Shenoy S, Nadler M, Turmelle Y, Shepherd R, Chapman WC, Lowell JA. The role of liver transplantation for hepatic adenomatosis in the pediatric population: case report and review of the literature. Pediatr Transplant. 2010 May;14(3):E16-9.

Turmelle YP, Nadler ML, Anderson CD, Doyle MB, Lowell JA, Shepherd RW. Towards minimizing immunosuppression in pediatric liver transplant recipients. Pediatr Transplant. 2009 Aug;13(5):553-9.

Weymann A, Hartman E, Gazit V, Wang C, Glauber M, Turmelle Y, Rudnick DA. p21 is required for dextrose-mediated inhibition of mouse liver regeneration. Hepatology. 2009 Jul;50(1):207-15.

Rudnick DA, Dietzen DJ, Turmelle YP, Shepherd R, Zhang S, Belle SH, Squires R; Pediatric Acute Liver Failure Study Group. Serum alpha-NH-butyric acid may predict spontaneous survival in pediatric acute liver failure. Pediatr Transplant. 2009 Mar;13(2):223-30.

Bennett WE Jr, Turmelle YP, Shepherd RW. Ibuprofen-induced liver injury in an adolescent athlete. Clin Pediatr (Phila). 2009 Jan;48(1):84-6.

Rudnick DA, Dietzen DJ, Turmelle Y, Shepherd R, Zhang S, Belle S, Squires R, and the Pediatric Acute Liver Failure Study Group, Serum [alpha]-NH2-Butyric Acid May Predict Spontaneous Survival in Pediatric Acute Liver Failure, Pediatric Transplantation, 2008 July.

Clark A, Weymann A, Hartman E, Turmelle Y, Carroll M, Thurman JM, Holers VM, Hourcade DE, Rudnick DA. Evidence for non-traditional activation of complement factor C3 during murine liver regeneration. Mol Immunol. 2008 Jun;45(11):3125-32.

Anderson CD, Turmelle YP, Lowell JA, Nadler M, Millis M, Anand R, Martz K, Shepherd RW; SPLIT Research Group. The effect of recipient-specific surgical issues on outcome of liver transplantation in biliary atresia. Am J Transplant. 2008 Jun;8(6):1197-204.

Wadhwani SI, Turmelle YP, Nagy R, Lowell J, Dillon P, Shepherd RW. Prolonged neonatal jaundice and the diagnosis of biliary atresia: a single-center analysis of trends in age at diagnosis and outcomes. Pediatrics. 2008 May;121(5):e1438-40.

Shepherd RW, Turmelle Y, Nadler M, Lowell JA, Narkewicz MR, McDiarmid SV, Anand R, Song C; SPLIT Research Group. Risk factors for rejection and infection in pediatric liver transplantation. Am J Transplant. 2008 Feb;8(2):396-403. Epub 2007 Dec 19.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Yumirle P. Turmelle.


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