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Neurology / Pediatric

Kelvin A. Yamada, MD

Current Position
Professor, Neurology and Pediatrics

Specialty Areas
Pediatric Neurology
Sleep Medicine
Pediatric Sleep Disorders

Patients Seen At
St Louis Children’s Hospital
One Children’s Place, Suite D, Second Floor
St. Louis, MO  63110
314-454-6120
Fax:   314-454-2523
View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Neurology
Campus Box 8111, 660 S. Euclid Ave
St. Louis, MO  63110

Areas of Clinical Interest
General neurology inpatient and outpatient care, newborn and pediatric inpatient neurological consultation, general inpatient pediatric medicine care, clinical neurophysiologist, pediatric sleep medicine.

Board Certification
Pediatric Neurology -- Certified
Pediatrics -- Certified
Neurology -- Certified
Sleep Medicine -- Eligible

Medical Education
B.A.: Pomona College, Claremont, California, 1980
Medical Degree: Baylor College of Medicine, Houston, Texas, 1983
Residency: Pediatrics, Baylor Affiliated Hospitals, Houston, Texas, 1984
Fellowship: Pediatric Neurology, Washington University School of Medicine, St. Louis, Missouri, 1988
Fellowship: Electroencephalography, Polysomnography, and Evoked Potentials, Washington University School of Medicine, St. Louis, Missouri, 1992
Hospital Affiliations
Barnes-Jewish Hospital
St. Louis Children's Hospital

Honors and Awards
Listed in Best Doctors in America, 2011-2013 (Best Doctors, Inc.)
American Neurological Association, Election, 2004

Invited Publications
Yamada, KA, Awadalla S: Chapter 24 Neurological Disorders, The Washington Manual of Medical Therapeutics, 32nd Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 2007.

Yamada, KA, Awadalla S: Chapter 24 Neurological Disorders, The Washington Manual of Medical Therapeutics, 31st Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 2004.

Yamada, KA: Therapeutic potential of AMPA receptor modulators in the treatment of neurological disease, Expert Opinion on Investigational Drugs, 2000,9: 765-777.

Yamada, KA, Awadalla S: Chapter 25 Neurological Disorders, The Washington Manual of Medical Therapeutics, 30th Edition, Lippincott-Raven, Hagerstown, MD, 2001.

Yamada, KA: Modulating excitatory synaptic neurotransmission: Potential treatment for neurological disease? Neurobiology of Disease, 1998,5: 67-80.

Yamada, KA: Neurology Pearls of Wisdom, 1st edition, Michael Labanowski, ed., Lincoln, NE, Boston Medical Publishing Corp., Neuropharmacology Chapter, p. 144, 1998.

Yamada, KA, Mozaffar T, Awadalla S: Chapter 26 Neurological Emergencies in Internal Medicine, The Washington Manual of Medical Therapeutics, 29th Edition, Lippincott-Raven, Hagerstown, MD, 1998.

Selected Publications
Shakkottai, VG, Xiao, M, Xu, L, Wong, M, Nerbonne, JM, Ornitz, DM, Yamada, KA: FGF14 Regulates the Intrinsic Excitability of Cerebellar Purkinje Neurons. Neurobiology of Disease. 2009; 33:81-88.

Xu, L, Rensing, N, Yang, X-F, Zhang, HX, Thio, LL, Rothman, SM, Weisenfeld, AE, Wong, M, Yamada, KA: Leptin inhibits 4-Aminopyridine and Pentylenetetrazole induced seizures and AMPAR mediated synaptic transmission. Journal of Clinical Investigation  2008, 118: 272-280.

Erbayat-Altay, E, Yamada, KA, Wong, M, Thio, LL: Increased severity of pentylenetetrazol induced seizures in leptin deficient ob/ob mice, Neuroscience Letters, 2008, 433: 82-86.

Farr, SA, Yamada, KA, Butterfield, DA, Abdul, HM, Xu, L, Miller, NE, Banks, WA, Morley, JE: Obesity and Hypertriglyceridemia Produce Cognitive Impairment. Endocrinology 2008; 149:2628-2636.

Diano, S, Farr, SA, Benoit, SC, McNay, EC, da Silva, I, Horvath, B, Gaskin, FS, Banks, WA, Morley, JE, Pinto, S, Sherwin, RS, Yamada, KA, Sleeman, MW, Tschop, MH and Horvath, T: Ghrelin controls hippocampal spine synapse density and memory performance. Nature Neuroscience 2006, 9: 381-388

Ouyang, Y, Wong, M, Capani, F, Rensing, N, Lee, C-S, Liu, Q, Martone, ME, Wu, JY, Yamada, KA, Ellisman, MH, Choi, DW: Transient decrease in F-actin may be necessary for translocation of proteins into dendritic spines, European Journal of Neuroscience, 2005, 22: 2995-3005

Yamada, KA, Rensing, N, Izumi, Y, de Erausquin, GA, Gazit, V, Dorsey, DA, Herrera, DG: Repetitive hypoglycemia in young rats impairs hippocampal long-term potentiation, Pediatric Research, 2004; 55:372-9

Karkar, KM, Thio, LL, Yamada, KA: Effects of Seven Clinically Important Antiepileptic Drugs on Inhibitory Glycine Receptor Currents in Hippocampal Neurons, Epilepsy Research, 2004;58: 27-35

Thio, LL, Yamada, KA: Differential presynaptic modulation of excitatory and inhibitory autaptic currents in cultured hippocampal neurons, Brain Research, 2004;1012: 22-28



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