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Ophthalmology and Visual Sciences

Rajendra S. Apte, MD, PhD

Current Position
Paul A. Cibis Distinguished Professor of Ophthalmology and Visual Sciences

Specialty Areas
Ophthalmology, Retina

Additional Features & Interviews with Dr. Apte:

Ask the Expert - Town & Style:  Diabetic Retinopathy

Patients Seen At
Washington University Eye Center in South County
13303 Tesson Ferry Road, Suite 100
St. Louis , MO  63128
Fax:   314-842-2316
View Driving Directions

Washington University Eye Center
Center for Advanced Medicine
4921 Parkview Place, Suite C, 12th Floor
St. Louis, MO  63110
Fax:   314-362-3725
View Floor Map  View Campus Map   View Driving Directions

Mailing Address
Washington University School of Medicine
Department of Ophthalmology and Visual Sciences
660 So. Euclid Avenue, Campus Box 8096
St. Louis, MO  63110

Areas of Clinical Interest
Diabetic retinopathy, macular surgery, macular holes, macular pucker, age-related macular degeneration, vitreous substitutes, retinal detachments

Board Certification
Ophthalmology -- Certified

Medical Education
Pre-Med: University of Bombay, Bombay, India, 1986
Medical Degree: L.T.M. Medical College, University of Bombay, Bombay, India, 1992
Ph.D.: Cellular and Molecular Biology, University of Texas Southwestern Medical Center, Dallas, Texas, 1997
Residency: Ophthalmology, UT Southwestern Medical Center, Dallas, Texas , 2001
Fellowship: Retinal Vascular, Wilmer Ophthalmological Institute, Baltimore, Maryland, 2002
Fellowship: Vitreoretinal, Wilmer Ophthalmological Institute, Baltimore, Maryland, 2003
Hospital Affiliations
Barnes-Jewish Hospital

Honors and Awards
Executive Committee Member, The Macula Society

Washington University Nominee for the Ellison Foundation New Scholars Award in Aging, 2005

Disclosure of Financial Interests with Industry
Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

Dr. Rajendra S. Apte reported the following earned financial interests during calendar year 2014. Move your mouse over a header for more info.
Royalties: When a faculty member invents or conceives a new or improved process or product, the company that manufactures the product will make royalty payments to the faculty member. Royalty payments usually are a small percentage of the company’s revenue related to that product.
Equity: Equity is an ownership interest in a company. Faculty members may be paid for their service to a company in stock or the option to obtain stock.
Consulting &
Advisory Boards
Consulting and Advisory Boards: Faculty may be paid to provide expertise to a company by being their consultant, or by serving on an advisory board.
Speaker Fees
Speaker Fees: Companies may pay faculty to speak to professional audiences about their products.
Genentech    $10,001-$25,000 
Opthlotech  Yes   
To learn more about Washington University's policies on collaborations with industry, click here.

Selected or Recent Journal Articles
Silberman DM, Ross K, Sande PH, Kubota S, Ramaswamy S, Apte RS, Mostoslavsky R. SIRT6 Is Required for Normal Retinal Function. PLoS One. 2014 Jun 4;9(6):e98831.

Rao RC, Choudhry N, Apte RS. Subconjunctival bevacizumab for iris neovascularisation - Authors' reply. Lancet Diabetes Endocrinol. 2014 Jun;2(6):450-1.

Stein LR, Wozniak DF, Dearborn JT, Kubota S, Apte RS, Izumi Y, Zorumski CF, Imai S. Expression of Nampt in hippocampal and cortical excitatory neurons is critical for cognitive function. J Neurosci. 2014 Apr 23;34(17):5800-15.

Sene A, Apte RS. Eyeballing cholesterol efflux and macrophage function in disease pathogenesis. Trends Endocrinol Metab. 2014 Mar;25(3):107-14.

Rao RC, Choudhry N, Apte RS. Regression of iris neovascularisation secondary to diabetic retinopathy with subconjunctival anti-VEGF therapy. Lancet Diabetes Endocrinol. 2014 Feb;2(2):182.

Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, Laird JM, Sene A, Apte RS, Salomon RG, Hollyfield JG, Perez VL. Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration. Int J Inflam. 2013;2013:503725.

Kempen JH, Sugar EA, Jaffe GJ, Acharya NR, Dunn JP, Elner SG, Lightman SL, Thorne JE, Vitale AT, Altaweel MM; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Fluorescein angiography versus optical coherence tomography for diagnosis of uveitic macular edema. Ophthalmology. 2013 Sep;120(9):1852-9.

Friedman DS, Holbrook JT, Ansari H, Alexander J, Burke A, Reed SB, Katz J, Thorne JE, Lightman SL, Kempen JH; MUST Research Group. Risk of elevated intraocular pressure and glaucoma in patients with uveitis: results of the multicenter uveitis steroid treatment trial. Ophthalmology. 2013 Aug;120(8):1571-9.

Zhao H, Roychoudhury J, Doggett TA, Apte RS, Ferguson TA. Age-dependent changes in FasL (CD95L) modulate macrophage function in a model of age-related macular degeneration. Invest Ophthalmol Vis Sci. 2013 Aug 7;54(8):5321-31.

Sene A, Khan AA, Cox D, Nakamura RE, Santeford A, Kim BM, Sidhu R, Onken MD, Harbour JW, Hagbi-Levi S, Chowers I, Edwards PA, Baldan A, Parks JS, Ory DS, Apte RS. Impaired cholesterol efflux in senescent macrophages promotes age-related macular degeneration. Cell Metab. 2013 Apr 2;17(4):549-61.

Dewan V, Lambert D, Edler J, Kymes S, Apte RS. Cost-effectiveness analysis of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology. 2012 Aug;119(8):1679-84.

Nguyen-Khoa BA, Goehring EL Jr, Werther W, Fung AE, Do DV, Apte RS, Jones JK. Hospitalized cardiovascular events in patients with diabetic macular edema. BMC Ophthalmol. 2012 May 30;12(1):11. [Epub ahead of print]

Sen HN, Drye LT, Goldstein DA, Larson TA, Merrill PT, Pavan PR, Sheppard JD, Burke A, Srivastava SK, Jabs DA; Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. Hypotony in patients with uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial. Ocul Immunol Inflamm. 2012 Apr;20(2):104-12.

Sun JK, Qin H, Aiello LP, Melia M, Beck RW, Andreoli CM, Edwards PA, Glassman AR, Pavlica MR; Diabetic Retinopathy Clinical Research Network. Evaluation of visual acuity measurements after autorefraction vs manual refraction in eyes with and without diabetic macular edema. Arch Ophthalmol. 2012 Apr;130(4):470-9.

Gangaputra SS, Altaweel MM, Peng Q, Friedman DS, Rao PK, Foster CS, Kim RY, Reed SB, Srivastava SK, Wong IG, Kempen JH; MUST Trial Research Group. Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trial. Ocul Immunol Inflamm. 2011 Aug;19(4):267-74

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Copyright 2015 Washington University School of Medicine