Milam A. Brantley, Jr., MD, PhD
Current Position
Assistant Professor, Ophthalmology and Visual Sciences
Specialty Areas
Ophthalmology, Retina
Retina
Mailing Address
|
Washington University School of Medicine Department of Ophthalmology and Visual Sciences
660 So. Euclid Avenue, Campus Box 8096
St. Louis,
MO
63110
|
Areas of Clinical Interest
Inherited retinal diseases, age-related macular degeneration, genetics of eye disease, diabetic retinopathy, electrophysiology of the eye
Board Certification
Ophthalmology
--
Certified
Medical Education
B.A. : Biology, Austin College, Sherman, Texas
, 1988
Ph.D.: Human and Molecular Genetics, Baylor College of Medicine, Houston, Texas
, 1996
Medical Degree: Baylor College of Medicine, Houston, Texas
, 1998
Residency: Ophthalmology, Barnes-Jewish Hospital at Washington University School of Medicine, St. Louis, Missouri
, 2002
Fellowship: Medical Retina and Inherited Retinal Diseases, Moorfields Eye Hospital, London, England
, 2003
Hospital Affiliations
Barnes-Jewish Hospital
Major or Recent Publications/Awards
Peer-Reviewed Manuscripts
Brantley MA Jr, Fang AM, King JM, Tewari A, Kymes SM, Shiels A. Association between CFH and LOC387715 genotypes and response of exudative AMD to intravitreal bevacizumab. Ophthalmology, 2007;114:2168-73.
Michaelides M, Chen LL, Brantley MA Jr, Andorf JL, Isaak EM, Jenkins SA, Holder GE, Bird AC, Stone EM, Webster AR. ABCA4 mutations and discordant ABCA4 alleles in patients and siblings with bull’s-eye maculopathy. Br J Ophthalmol, 2007;91:1650-5.
Brantley MA Jr, Edelstein SL, King JM, Apte RS, Kymes SM, Shiels A. Clinical phenotypes associated with the Complement Factor H Y402H variant in age-related macular degeneration. Am J Ophthalmol, 2007;144:404-8.
Knopf HL, Carter K, Council MD, Brantley MA Jr. Peripapillary Hemorrhage. Compr Ophthalmol Update 2007;8:53-4.
Zhu Y, Zhang Y, Ojwang BA, Brantley MA Jr, Gidday JM. Long-term tolerance to retinal ischemia by repetitive hypoxic preconditioning:role of HIF-1 α and Heme Oxygenase-1. Invest Ophthalmol Vis Sci 2007; 45:1735-43.
Feiner L, Barr EE, Shui YB, Holekamp NM, Brantley MA Jr. Safety of intravitreal injection of bevacizumab in rabbit eyes. Retina 2006, 882-8.
Michaelides M, Jenkins S, Brantley MA Jr, Andrews RM, Waseem N, Gregory-Evans K, Bhattacharya S, Fitzke FW, Webster AR. Maculopathy due to the R345W substitution in fibulin-3: distinct clinical features, disease variability and extent of retinal dysfunction. Invest Ophthalmol Vis Sci 2006; 47:3085-97..
Brantley MA Jr. Update on pigmentary retinal dystrophies. Comprehensive Ophthalmology Update 2005; 6:237-53.
Mantel I, Brantley MA Jr, Bellman C, Robson AG, Holder GE, Taylor A, Anderson G, Moore AT. Juvenile Neuronal Lipofuscinosis (Batten Disease) CLN3 mutation (Chrom 16p11.2) with different phenotypes in a sibling pair and low intensity invivo autofluorescence. Klin Monatsbl Augenheilkd 2004; 221:427-30.
Harbour JW, Brantley MA Jr, Hollingsworth H, Gordon ME. Association between choroidal pigmentation and posterior uveal melanoma in a Caucasian population. Br J Ophthalmol 2004; 88:39-43.
Harbour JW, Brantley MA Jr, Hollingsworth H, Gordon ME. Association between choroidal pigmentation and iris freckles, iris naevi and choroidal naevi. Br J Ophthalmol 2004; 88:36-38.
Joseph DP, Brantley MA Jr, Grand MG. Serpiginous choroiditis in a patient with cardiac sarcoidosis. Retina 2003; 23:116-117.
Brantley MA Jr, Worley L, Harbour JW. Altered expression of Rb and p53 in uveal melanoma following plaque radiotherapy. Am J Ophthalmol 2002; 133:242-248.
Brantley MA Jr and Harbour JW. The molecular biology of retinoblastoma. Ocul Immunol Inflamm 2001; 9:1-8
Brantley MA Jr and Harbour JW. Deregulation of the Rb and p53 pathways in uveal melanoma. Am J Pathol 2000; 157:1795-1801.
Brantley MA Jr and Harbour JW. Inactivation of the Rb pathway in uveal melanoma. Cancer Res 2000; 60:4320-4323.