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Pediatrics

Thomas W. Ferkol, Jr., MD

Current Position
Alexis Hartmann Professor, Pediatrics
Division of Pediatric Allergy, Immunology and Pulmonary Medicine
Director, Division of Pediatric Allergy, Immunology and Pulmonary Medicine


Specialty Areas
Pediatric Pulmonary Disease
Pediatric Asthma
Pediatric Cystic Fibrosis

Patients Seen At
St. Louis Children's Hospital
One Children's Place, Second Floor, Suite C
St. Louis, MO  63110
314-454-2694
Fax:   314-454-2515
View Driving Directions

Mailing Address
Washington University School of Medicine
660 S. Euclid Avenue, Campus Box 8116
St. Louis, MO  63110

Areas of Clinical Interest
Cystic fibrosis, pulmonary inflammation and disease in children

Board Certification
Pediatrics -- Certified
Pediatric Pulmonary Disease -- Certified

Medical Education
B.S.: Case Western Reserve University, Cleveland, Ohio, 1981
Medical Degree: Ohio State University College of Medicine, Cleveland, Ohio, 1985
Residency: Pediatrics, University of North Carolina, Chapel Hill, North Carolina, 1988
Fellowship: Pediatric Pulmonology, Case Western Reserve University, Cleveland, Ohio, 1989
Chief Resident: University of North Carolina, Chapel Hill, North Carolina, 1989
Hospital Affiliations
Barnes-Jewish Hospital
Missouri Baptist Medical Center
St. Louis Children's Hospital

Honors and Awards
Listed in Best Doctors in America, 2003-2013 (Best Doctors, Inc.)
Floyd Denny Award, Pediatric Society
Trustees Award, Rainbow Babies and Children's Hospital

Selected or Recent Journal Articles
Cohen-Cymberknoh M, Kerem E, Ferkol T, Elizur A. Airway inflammation in cystic fibrosis: molecular mechanisms and clinical implications. Thorax. 2013 May 23.

Davis SD, Ferkol T. Identifying the origins of cystic fibrosis lung disease. N Engl J Med. 2013 May 23;368(21):2026-8. No abstract available.

Horani A, Ferkol TW, Shoseyov D, Wasserman MG, Oren YS, Kerem B, Amirav I, Cohen-Cymberknoh M, Dutcher SK, Brody SL, Elpeleg O, Kerem E. LRRC6 mutation causes primary ciliary dyskinesia with dynein arm defects. PLoS One. 2013;8(3):e59436.

Antony D, Becker-Heck A, Zariwala MA, Schmidts M, Onoufriadis A, Forouhan M, Wilson R, Taylor-Cox T, Dewar A, Jackson C, Goggin P, Loges NT, Olbrich H, Jaspers M, Jorissen M, Leigh MW, Wolf WE, Daniels ML, Noone PG, Ferkol TW, Sagel SD, Rosenfeld M, Rutman A, Dixit A, O'Callaghan C, Lucas JS, Hogg C, Scambler PJ, Emes RD; Uk10k, Chung EM, Shoemark A, Knowles MR, Omran H, Mitchison HM. Mutations in CCDC39 and CCDC40 are the major cause of primary ciliary dyskinesia with axonemal disorganization and absent inner dynein arms. Hum Mutat. 2013 Mar;34(3):462-72.

Ferkol TW, Puffenberger EG, Lie H, Helms C, Strauss KA, Bowcock A, Carson JL, Hazucha M, Morton DH, Patel AC, Leigh MW, Knowles MR, Zariwala MA. Primary Ciliary Dyskinesia-Causing Mutations in Amish and Mennonite Communities. J Pediatr. 2013 Mar 7.

Knowles MR, Leigh MW, Ostrowski LE, Huang L, Carson JL, Hazucha MJ, Yin W, Berg JS, Davis SD, Dell SD, Ferkol TW, Rosenfeld M, Sagel SD, Milla CE, Olivier KN, Turner EH, Lewis AP, Bamshad MJ, Nickerson DA, Shendure J, Zariwala MA; Genetic Disorders of Mucociliary Clearance Consortium. Exome sequencing identifies mutations in CCDC114 as a cause of primary ciliary dyskinesia. Am J Hum Genet. 2013 Jan 10;92(1):99-106.

Ross K, Chmiel JF, Ferkol T. The impact of the Clean Air Act. J Pediatr. 2012 Nov;161(5):781-6.

Horani A, Druley TE, Zariwala MA, Patel AC, Levinson BT, Van Arendonk LG, Thornton KC, Giacalone JC, Albee AJ, Wilson KS, Turner EH, Nickerson DA, Shendure J, Bayly PV, Leigh MW, Knowles MR, Brody SL, Dutcher SK, Ferkol TW. Whole-exome capture and sequencing identifies HEATR2 mutation as a cause of primary ciliary dyskinesia. Am J Hum Genet. 2012 Oct 5;91(4):685-93.

Knowles MR, Leigh MW, Carson JL, Davis SD, Dell SD, Ferkol TW, Olivier KN, Sagel SD, Rosenfeld M, Burns KA, Minnix SL, Armstrong MC, Lori A, Hazucha MJ, Loges NT, Olbrich H, Becker-Heck A, Schmidts M, Werner C, Omran H, Zariwala MA; Genetic Disorders of Mucociliary Clearance Consortium. Mutations of DNAH11 in patients with primary ciliary dyskinesia with normal ciliary ultrastructure. Thorax. 2012 May;67(5):433-41.

Ferkol TW, Leigh MW. Ciliopathies: the central role of cilia in a spectrum of pediatric disorders. J Pediatr. 2012 Mar;160(3):366-71.

Chuen-im P, Smyth MD, Segura B, Ferkol T, Rivera-Spoljaric K. Recurrent pleural effusion without intrathoracic migration of ventriculoperitoneal shunt catheter: a case report. Pediatr Pulmonol. 2012 Jan;47(1):91-5.

Zariwala MA, Omran H, Ferkol TW. The emerging genetics of primary ciliary dyskinesia.
Proc Am Thorac Soc. 2011 Sep;8(5):430-3.

Olin JT, Burns K, Carson JL, Metjian H, Atkinson JJ, Davis SD, Dell SD, Ferkol TW, Milla CE, Olivier KN, Rosenfeld M, Baker B, Leigh MW, Knowles MR, Sagel SD; for the Genetic Disorders of Mucociliary Clearance Consortium. Diagnostic yield of nasal scrape biopsies in primary ciliary dyskinesia: A multicenter experience. Pediatr Pulmonol. 2011 Jan 31.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Thomas W. Ferkol.

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