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Radiology / Diagnostic - Pediatric

Robert C. McKinstry, III, MD, PhD

Current Position
Professor, Radiology
Division of Diagnostic Radiology
Pediatric Radiology and Neuroradiology Sections
Chief, Pediatric Radiology
Professor, Pediatrics

Specialty Areas
Pediatric Neuroradiology
Neuro Oncology
Pediatric Radiology

Patients Seen At
Mallinckrodt Institute of Radiology
510 South Kingshighway Boulevard
St. Louis , MO  63110
Fax:   314-362-4886
View Driving Directions

Mailing Address
Washington University School of Medicine, Department of Radiology
660 South Euclid Avenue, Campus Box 8131
St. Louis, MO  63110

Areas of Clinical Interest
Magnetic resonance imaging, MRI, MR imaging of brain development, diffusion tensor imaging, perfusion MR imaging and functional MR imaging, functional neuroimaging with magnetic resonance

Board Certification
Radiology -- Certified
Neuroradiology -- Certified

Medical Education
B.S.: Boston University, Boston, Massachusetts, 1984
Ph.D.: Radiological Sciences, Massachusetts Institute of Technology, Boston, Massachusetts, 1991
Medical Degree: Harvard-MIT Division of Health Sciences & Technology, Harvard Medical School, Boston, Massachusetts, 1992
Residency: Mallinckrodt Institute of Radiology and Barnes-Jewish Hospital, St. Louis, Missouri, 1997
Fellowship: Mallinckrodt Institute of Radiology, Washington University, St. Louis, Missouri, 1999
Hospital Affiliations
Barnes-Jewish Hospital
Barnes-Jewish West County Hospital
St. Louis Children's Hospital

Honors and Awards
Listed in Best Doctors in America, 2008-2013 (Best Doctors, Inc.)
RSNA Roentgen Resident/Fellow Research Award, Mallinckrodt Institute of Radiology, 1997
Distinguish Teacher Award, Mallinckrodt Institute of Radiology, Washington University, 2002-2005
Diagnostic Radiology Teacher of the Year, Mallinckrodt Institute of Radiology, Washington University, 2007
Fellow, American College of Radiology, 2014

Disclosure of Financial Interests with Industry
Washington University and its physicians are committed to ensuring integrity and objectivity in medical decision-making. Some of our physicians work collaboratively with pharmaceutical or medical device companies to develop innovative ideas and products that can improve health care delivery and clinical outcomes for patients. In some instances, our faculty physicians are paid by these commercial companies to provide advice on product design or to speak about the use of medications, devices, equipment or procedures. These payments may include: a) compensation for consulting and speaking engagements, b) equity, and/or c) royalties for products invented by our faculty. Any payments to Washington University physicians must be based on tangible services and may not exceed fair market value for their work. In addition to disclosure on this web site, physicians earning more than $10,000 per year must disclose their corporate financial relationship in writing to patients when prescribing or using that company's products.

Dr. Robert C. McKinstry reported the following earned financial interests during calendar year 2014. Move your mouse over a header for more info.
Royalties: When a faculty member invents or conceives a new or improved process or product, the company that manufactures the product will make royalty payments to the faculty member. Royalty payments usually are a small percentage of the company’s revenue related to that product.
Consulting &
Advisory Boards
Consulting and Advisory Boards: Faculty may be paid to provide expertise to a company by being their consultant, or by serving on an advisory board.
Speaker Fees
Speaker Fees: Companies may pay faculty to speak to professional audiences about their products.
Siemans  $10,001-$25,000  
To learn more about Washington University's policies on collaborations with industry, click here.

Selected or Recent Journal Articles
Hood A, Antenor-Dorsey JA, Rutlin J, Hershey T, Shimony JS, McKinstry RC, Grange DK, Christ SE, Steiner R, White DA. Prolonged exposure to high and variable phenylalanine levels over the lifetime predicts brain white matter integrity in children with henylketonuria. Mol Genet Metab. 2015 Jan;114(1):19-24. doi: 0.1016/j.ymgme.2014.11.007. Epub 2014 Nov 13. PubMed PMID: 25481106; PubMed Central PMCID: PMC4277899.

DeBaun MR, Gordon M, McKinstry RC, Noetzel MJ, White DA, Sarnaik SA, Meier ER, Howard TH, Majumdar S, Inusa BP, Telfer PT, Kirby-Allen M, McCavit TL, Kamdem A, Airewele G, Woods GM, Berman B, Panepinto JA, Fuh BR, Kwiatkowski JL, King AA, Fixler JM, Rhodes MM, Thompson AA, Heiny ME, Redding-Lallinger RC, Kirkham FJ, Dixon N, Gonzalez CE, Kalinyak KA, Quinn CT, Strouse JJ, Miller JP, Lehmann H, Kraut MA, Ball WS Jr, Hirtz D, Casella JF. Controlled trial of transfusions for silent cerebral infarcts in sickle cell anemia. N Engl J Med. 2014 Aug 21;371(8):699-710. doi: 10.1056/NEJMoa1401731. PubMed PMID: 25140956; PubMed Central PMCID: PMC4195437.

Liem RI, Liu J, Gordon MO, Vendt BA, McKinstry RC 3rd, Kraut MA, Strouse JJ, Ball WS, DeBaun MR. Reproducibility of detecting silent cerebral infarcts in pediatric sickle cell anemia. J Child Neurol. 2014 Dec;29(12):1685-91. doi: 10.1177/0883073813506491. Epub 2013 Dec 5. PubMed PMID: 24309240; PubMed Central PMCID: PMC4096057.

Rajagopal A, Shimony JS, McKinstry RC, Altaye M, Maloney T, Mangano FT, Limbrick DD, Holland SK, Jones BV, Simpson S, Mercer D, Yuan W. White matter microstructural abnormality in children with hydrocephalus detected by probabilistic diffusion tractography. AJNR Am J Neuroradiol. 2013 Dec;34(12):2379-85. doi: 10.3174/ajnr.A3737. Epub 2013 Sep 26. PubMed PMID: 24072621; PubMed Central PMCID: PMC4168018.

White DA, Antenor-Dorsey JA, Grange DK, Hershey T, Rutlin J, Shimony JS, McKinstry RC, Christ SE. White matter integrity and executive abilities following treatment with tetrahydrobiopterin (BH4) in individuals with phenylketonuria. Mol Genet Metab. 2013 Nov;110(3):213-7. doi: 10.1016/j.ymgme.2013.07.010. Epb 2013 Jul 19. PubMed PMID: 23928118; PubMed Central PMCID: PMC3832288.

Ji J, Shimony J, Gao F, McKinstry RC, Gutmann DH. Optic nerve tortuosity in children with neurofibromatosis type 1. Pediatr Radiol. 2013 Oct;43(10):1336-43. doi: 10.1007/s00247-013-2694-1. Epub 2013 May 2. Erratum in: Pediatr Radiol. 2013 Oct;43(10):1418. PubMed PMID: 23636538; PubMed Central PMCID: PMC3904184.

Antenor-Dorsey JA, Hershey T, Rutlin J, Shimony JS, McKinstry RC, Grange DK, Christ SE, White DA. White matter integrity and executive abilities in individuals with henylketonuria. Mol Genet Metab. 2013 Jun;109(2):125-31. doi: 10.1016/j.ymgme.2013.03.020. Epub 2013 Apr 6. PubMed PMID: 23608077; PubMed Central PMCID: PMC3678378.

Linscott LL, Kessler MM, Kitchin DR, Quayle KS, Hildebolt CF, McKinstry RC, Don S. CT for pediatric, acute, minor head trauma: clinician conformity to published guidelines. AJNR Am J Neuroradiol. 2013 Jun-Jul;34(6):1252-6. doi: 10.3174/ajnr.A3366. Epub 2012 Dec 6. PubMed PMID: 23221949.

Quinn CT, McKinstry RC, Dowling MM, Ball WS, Kraut MA, Casella JF, Dlamini N, Ichord RN, Jordan LC, Kirkham FJ, Noetzel MJ, Roach ES, Strouse JJ, Kwiatkowski JL, Hirtz D, DeBaun MR. Acute silent cerebral ischemic events in children with sickle cell anemia. JAMA Neurol. 2013 Jan;70(1):58-65. doi: 10.1001/jamaneurol.2013.576. PubMed PMID: 23108767; PubMed Central PMCID: PMC3677221.

Thangarajh M, Yang G, Fuchs D, Ponisio MR, McKinstry RC, Jaju A, Noetzel MJ, Casella JF, Barron-Casella E, Hooper WC, Boulet SL, Bean CJ, Pyle ME, Payne AB, Driggers J, Trau HA, Vendt BA, Rodeghier M, DeBaun MR. Magnetic resonance angiography-defined intracranial vasculopathy is associated with silent cerebral infarcts and glucose-6-phosphate dehydrogenase mutation in children with sickle cell anaemia. Br J Haematol. 2012 Nov;159(3):352-9. doi: 10.1111/bjh.12034. Epub 2012 Sep 7. PubMed PMID: 22958163; PubMed Central PMCID: PMC3775590.

Yuan W, McKinstry RC, Shimony JS, Altaye M, Powell SK, Phillips JM, Limbrick
DD Jr, Holland SK, Jones BV, Rajagopal A, Simpson S, Mercer D, Mangano FT. Diffusion tensor imaging properties and neurobehavioral outcomes in children with hydrocephalus. AJNR Am J Neuroradiol. 2013 Feb;34(2):439-45. doi: 10.3174/ajnr.A3218. Epub 2012 Aug 16. PubMed PMID: 22899790; PubMed Central PMCID: PMC4168017.

Hazlett HC, Gu H, McKinstry RC, Shaw DW, Botteron KN, Dager SR, Styner M, Vachet C, Gerig G, Paterson SJ, Schultz RT, Estes AM, Evans AC, Piven J; IBIS Network. Brain volume findings in 6-month-old infants at high familial risk for autism. Am J Psychiatry. 2012 Jun;169(6):601-8. doi: 10.1176/appi.ajp.2012.11091425. PubMed PMID: 22684595; PubMed Central PMCID: PMC3744332.

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