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Radiology / Diagnostic - Pediatric

William H. McAlister , MD

Current Position
Professor, Radiology
Division of Diagnostic Radiology
Professor, Pediatrics

Specialty Areas
Pediatric Radiology
Diagnostic Radiology

Patients Seen At
St Louis Children’s Hospital
One Children’s Place
St. Louis, MO  63110
View Driving Directions

Mailing Address
Washington University School of Medicine, Department of Radiology
660 South Euclid Avenue, Campus Box 8131
St. Louis, MO  63110

Areas of Clinical Interest
Bone and mineral research, bone and joint disorders, human genetics, skeletal dysplasias

Board Certification
Radiology -- Certified
Pediatric Radiology -- Certified

Medical Education
BS: Wayne State University, Detroit, Michigan
Medical Degree: Wayne State University College of Medicine, Detroit, Michigan
Residency-Fellowship: Radiology, Cincinnati General Hospital, Cincinnati, Ohio
Hospital Affiliations
Barnes-Jewish Hospital
Shriners Hospital
St. Louis Children's Hospital

Honors and Awards
Distinguished Service Award, Washington University, 2006
Distinguished Service Award, St. Louis Children’s Hospital, 2006
Fellow, American College of Radiology
Winner of Gold Medal of the Society for Pediatric Radiology, 1998
Winner, Caffey Society Award, Society for Pediatric Radiology 1983

Editorial Responsibilities
American Journal of Roentgenology, Radiology, Pediatric Radiology, Radiographics,

Editorial Board Member
Pediatric Radiology

Selected or Recent Journal Articles
Mumm S, Huskey M, Cajic A, Wollberg V, Zhang F, Madson KL, Wenkert D, McAlister WH, Gottesman GS, Whyte MP. PHEX 3'-UTR c.*231A>G Near The Polyadenylation Signal is a Relatively Common, Mild, American Mutation That Masquerades as Sporadic or X-Linked Recessive Hypophosphatemic Rickets.  J Bone Miner Res. 2015 Jan;30(1):137-43

Schafer AL, Mumm S, … McAlister WH. Panostotic expansile bone disease with massive jaw tumor formation and a novel mutation in the signal peptide of RANK. J Bone Mineral Res. 2014 April.

Saki F, Karamizadeh Z, Nasirabadi S, Mumm S, McAlister WH, Whyte MP:
Juvenile Paget’s Disease In An Iranian Kindred With Vitamin D Deficiency And Novel Homozygous TNFRSF11B Mutation. J Bone Mineral Res. 2013.

Otero JE, Gottesman GS, McAlister WH, … Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy. J Bone Mineral Res. 2013 Feb.

Whyte MP, Greenberg CR, … McAlister WH. Enzyme-replacement therapy in life-threatening hypophosphatasia. New England J of Med. 2012.

Lindahl K, Barnes AM, … McAlister WH. COL1 C-propeptide cleavage site mutations cause high bone mass osteogenesis imperfecta. Human Mutat. 2011.

Whyte MP, Stolina M, McAlister WH, … Hajdu-Cheney Syndrome: Serum biomarker profiling, bone radiography and histopathology, and germline mutation analysis indicate complex dysregulation of skeletal cells from gain-of-function truncation of NOTCH2. J Bone Mineral Res. 2011.

Wenkert D, McAlister WH, Coburn SP, … Hypophosphatasia: nonlethal disease despite skeletal presentation in utero (17 new cases and literature review). J Bone Mineral Res. 2011 Oct.

Whyte MP, Wenkert D, McAlister, WH, … Dysosteosclerosis presents as an "Osteoclast-poor" form of Osteopetrosis: Comprehensive Investigation of a 3-year-old girl and literature review. J Bone Mineral Res, 2010.

Whyte M, Greenberg CR, McAlister WH, … Hypophosphatasia: Enzyme Replacement Therapy for Children Using Bone-Targeted, Tissue-Nonspecific Alkaline Phosphatase. J Bone Mineral Res. 2010.

Whyte MP, Kempa L, McAlister WH, Zhang F, Mumm S, Wenkert D. Elevated Serum Lactate Dehydrogenase Isoenzymes And Aspartate Transaminase Distinguish Albers-Schönberg Disease (Chloride Channel 7 Deficiency Osteopetrosis) Among The Sclerosing Bone Disorders. J Bone Mineral Res. 2010.

McAlister WH, Herman TE, Kronemer KA. Selected Syndromes and Chromosomal Disorders In Caffey’s Pediatric Diagnostic Imaging, Editors Kuhn JP, Slovis TL, Haller JO, Mosby, 2008, 11th Edition, Vol 2, Section VIII, Part VI, pg 166.

Whyte MP, McAlister WH, Novack DV, … Bisphosphonate-induced Osteopetrosis: Novel Bone Modeling Defects, Metaphyseal osteopenia, and osteosclerosis fractures after drug exposure ceases, J Bone Mineral Res. 2008

Wenkert D, Mumm S, … McAlister WH, Whyte MP. Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy, Clinical Orthopaedics and Related Research. 2007.

McAlister WH, Herman TE. Osteochondrodysplasias, Dysostoses, Chromosomal Aberrations, Mucopolysaccharidoses, Mucolipidoses In Resnicks Book of Bone and Joint Imaging, Editors Resnick D, Kransdorf MJ, Elsevier Saunders, 2005, 3rd Edition, Pgs 1298 -1325.

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Copyright 2015 Washington University School of Medicine