Ophthalmology and Visual Sciences

Our nationally renown ophthalmologic specialists offer patient care in the following areas general ophthalmology, pediatric ophthalmology, cornea, retina and refractive surgery, glaucoma, optometry, neuro ophthalmology, oculoplastics, ocular oncology and pathology. Whether you need a routine eye exam or a refractive surgeon, there is a physician in our Department who can provide for your eye health care needs.

Text Size: S M L

Home > Physicians Directory > Ophthalmology and Visual Sciences

J. William Harbour, MD

Specialty Areas
Retina
Ocular Oncology

Areas of Clinical Interest
Ocular oncology, uveal melanoma, retinoblastoma, eye cancer, iris tumors, ocular cancer, ocular melanoma, other intraocular tumors



Visit the Eye Tumor web site for more information on Ocular Oncology

Major or Recent Publications/Awards

Honors and Awards

Listed in Best Doctors in America, 2003 - 2009 (Best Doctors, Inc)
Listed in America's Top Doctors, Castle Connolly Medical Ltd., 2005 - 2008

Books and Book Chapters

Harbour JW, Char DH. Intraocular lymphoid tumors; Retina, Vitreous, Macula: A Comprehensive Text. Eds. Chang S, Shields J, Green WR. Philadelphia, PA: WB Saunders Co, 1998

Harbour JW, Murray TG. Management of intraocular tumors. Ed. Albert D. Ophthalmic Surgery: Principles and Techniques. Oxford, England: Blackwell Co, 1998

Augsburger JJ, Harbour JW. Uveal Nevus. Ophthalmology. M. Yanoff and J. Duker, Eds. Mosby, London, 1998

Journal Articles

Harbour JW, Worley L, Ma D, Cohen M.
Transducible Peptide therapy for uveal melanoma and retinoblastoma. Arch Ophthalmol 2002 Oct; 120(10):1341-6

Brantley MA Jr, Worley L, Harbour JW.
Altered expression of Rb and p53 in uveal melanomas following plaque radiotherapy. Am J Ophthalmol 2002 Feb; 133(2):242-8

Brantley MA Jr, Harbour JW. Deregulation of the Rb and p53 pathways in uveal melanoma. Am J Pathol 2000 Dec; 157(6):1795-801

Brantley MA Jr, Harbour JW. Inactivation of retinoblastoma protein in uveal melanoma by phosphorylation of sites in the COOH-terminal region.
Cancer Res 2000 Aug 15; 60(16):4320-3

Harbour JW. Tumor suppressor genes in ophthalmology. Survey of Ophthalmology 1999

Harbour JW, et al. CDK phosphorylation riggers intramolecular interactions that progressively block Rb functions as cells move through GI. Cell 1999

Harbour JW. Overview of RB gene mutations in retinoblastoma: Implications for clinical genetic screening. Ophthalmology 1998; 105:1442-7

Harbour JW, Char DH. Langerhans-cell histiocytosis diagnosed by fine needle biopsy. Arch Ophthalmol 1997; 115:1212-3

Harbour JW, Char DH. Metastic risk for distinct patterns of post-irradiation local recurrence of posterior uveal melanoma. Ophthalmology 1997; 104:1785-93

Harbour JW, Murray TG. Intraoperative echographic localizatoin of I-125 episcleral radioactive plaques for posterior uveal melanoma. Retina 1996; 16:129-34

Harbour JW, Murray TG. Local carboplatin therapy in transgenic murine retinoblastoma. Invest Ophthalmology Vis Sci 1996; 37:1892-8

Harbour JW, Augsburger JJ, Eagle RC. Initial management and follow-up of melanocytic iris tumors. Ophthalmology 1995; 102:1987-93

Harbour JW, DePotter P, Shields CL, Shields JA. Uveal metastasis from carcinoid tumor: Clinical observations in nine cases. Ophthalmology 1994; 101:1084-90

Harbour JW. Abnormalities in structure and expression of the human retinoblastoma gene in SCLC. Science 1988; 241:353-357


For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. J. William Harbour

J. William Harbour, MD