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Scott Saunders, MD, PhD

Current Position
Associate Professor, Pediatrics
Associate Professor, Molecular Biology & Pharmacology

Specialty Areas
Newborn Medicine - Neonatology
Neonatal/Perinatal Medicine

Patients Seen At
St Louis Children's Hospital
One Children's Place, Neonatal Intensive Care Unit (NICU), 5th Floor
St. Louis, MO  63110
Fax:   314-454-4633
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Mailing Address
Washington University School of Medicine
660 S. Euclid Avenue, Campus Box 8116
St. Louis, MO  63110

Areas of Clinical Interest
genetic epidemiology, Simpson Golabi Behmel Syndrome, blood coagulation hemeostasis, skeletal development

Board Certification
Pediatrics -- Certified

Medical Education
B.S.: University of Minnesota, Minneapolis, MN, 1983
Medical School: Stanford University School of Medicine, Stanford, CA, 1990
Residency: Medicine, Children's Hospital, Boston, MA, 1993
Research Fellowship: Newborn Medicine, Children's Hospital, Boston, MA, 1993
Fellowship: Brain & Cognitive Sciences, Massachusetts Institute of Technololgy, Cambridge, MA, 1995
Fellowship: Newborn Medicine, Harvard Medical School, Boston, MA, 1996
Hospital Affiliations
St. Louis Children's Hospital

Honors and Awards
Spoehrer Scholar in Pediatrics 1999

Selected or Recent Journal Articles
Thach BT, Kenney-Hunt JP, Simon TC, Stratman JL, Thach SB, Harris KA, Saunders S, Cheverud JM. Sex-specific quantitative trait loci linked to autoresuscitation failure in SWR/J mice. Heredity (Edinb). 2009 Dec;103(6):469-75.

Ng A, Wong M, Viviano B, Erlich JM, Alba G, Pflederer C, Jay PY, Saunders S. Loss of glypican-3 function causes growth factor-dependent defects in cardiac and coronary vascular development. Dev Biol. 2009 Nov 1;335(1):208-15.

Vachharajani A, Bethin K, Mouillet JF, Sadovsky Y, Saunders S. The rare occurrence of absent adrenals in a term infant: a case report and review of the literature. Am J Perinatol. 2006 Feb;23(2):111-4. Review.

Vachharajani A, Saunders S. Allelic variation in the serotonin transporter (5HTT) gene contributes to idiopathic pulmonary hypertension in children. Biochem Biophys Res Commun. 2005 Aug 26;334(2):376-9.

Viviano BL, Silverstein L, Pflederer C, Paine-Saunders S, Mills K, Saunders S. Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62.

Viviano BL, Paine-Saunders S, Gasiunas N, Gallagher J, Saunders S. Domain-specific modification of heparan sulfate by Qsulf1 modulates the binding of the bone morphogenetic protein antagonist Noggin. J Biol Chem. 2004 Feb 13;279(7):5604-11. Epub 2003 Nov 25.

Paine-Saunders S, Viviano BL, Economides AN, Saunders S. Heparan sulfate proteoglycans retain Noggin at the cell surface: a potential mechanism for shaping bone morphogenetic protein gradients. J Biol Chem. 2002 Jan 18;277(3):2089-96. Epub 2001 Nov 12.

DeBaun MR, Ess J, Saunders S. Simpson Golabi Behmel syndrome: progress toward understanding the molecular basis for overgrowth, malformation, and cancer predisposition. Mol Genet Metab. 2001 Apr;72(4):279-86. Review.

Paine-Saunders S, Viviano BL, Zupicich J, Skarnes WC, Saunders S. glypican-3 controls cellular responses to Bmp4 in limb patterning and skeletal development. Dev Biol. 2000 Sep 1;225(1):179-87.

Paine-Saunders S, Viviano BL, Saunders S. GPC6, a novel member of the glypican gene family, encodes a product structurally related to GPC4 and is colocalized with GPC5 on human chromosome 13. Genomics. 1999 May 1;57(3):455-8.

Paine-Saunders S, Viviano BL, Zupicich J,Skarnes WC, Saunders S. Genetic evidence of an interaction between Glypican-3 and Bmp4 in limb patterning and skeletal development. Submitted

Saunders S, Fesenko J, Lander AD. Identification and characterization of neural specific elements of the cerebroglycan (glypican-2) promoter. Manuscript in preparation.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Scott Saunders.

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Copyright 2015 Washington University School of Medicine