Rebecca L. Aft, MD, PhD
Division of General Surgery
Cancer and Endocrine Surgery Section
Areas of Clinical Interest
Washington University School of Medicine
Department of Surgery
660 S. Euclid Avenue, Campus Box 8109
breast disease, breast cancer, oncology, general surgery, endocrine cancer, melanoma surgery, sarcoma
Areas of Research Interest
breast disease, breast cancer, oncology
B.S.: University of Wisconsin, Madison, Wisconsin, 1978
Ph.D.: University of Wisconsin, Madison, Wisconsin, 1983
Medical Degree: Washington University School of Medicine, St. Louis, MO, 1992
Honors and Awards
Barnes-Jewish West County Hospital
John Cochran Veterans Hospital
Listed in Best Doctors in America, 2008-2013 (Best Doctors, Inc.)
Selected or Recent Journal Articles
Cyr A, Gao F, Gillanders WE, Aft RL, Eberlein TJ, Margenthaler JA. Disease Recurrence in Sentinel Node-Positive Breast Cancer Patients Forgoing Axillary Lymph Node Dissection. Ann Surg Oncol. 2012 Aug 14.
Garsa AA, Ferraro DJ, Dewees T, Margenthaler JA, Naughton M, Aft R, Gillanders WE, Eberlein T, Matesa MA, Zoberi I. Analysis of fat necrosis after adjuvant high-dose-rate interstitial brachytherapy for early stage breast cancer. Brachytherapy. 2012 Jun 20.
Aft RL, Naughton M, Trinkaus K, Weilbaecher K. Effect of (Neo)adjuvant zoledronic acid on disease-free and overall survival in clinical stage II/III breast cancer. Br J Cancer. 2012 Jun 26.
Yu J, Mushawah FA, Taylor ME, Cyr AE, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA. Compromised margins following mastectomy for stage I-III invasive breast cancer. J Surg Res. 2012 Apr 10.
Atkins J, Mushawah FA, Appleton CM, Cyr AE, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA. Positive margin rates following breast-conserving surgery for stage I-III breast cancer: Palpable versus nonpalpable tumors. J Surg Res. 2012 Apr 10.
Jeffe DB, Pérez M, Liu Y, Collins KK, Aft RL, Schootman M. Quality of life over time in women diagnosed with ductal carcinoma in situ, early-stage invasive breast cancer, and age-matched controls. Breast Cancer Res Treat. 2012 Jul.
Ferraro DJ, Garsa AA, DeWees TA, Margenthaler JA, Naughton M, Aft R, Gillanders WE, Eberlein T, Matesa MA, Zoberi I. Comparison of accelerated partial breast irradiation via multicatheter interstitial brachytherapy versus whole breast radiation. Radiat Oncol. 2012 Mar 29.
Ma CX, Cai S, Li S, Ryan CE, Guo Z, Schaiff WT, Lin L, Hoog J, Goiffon RJ, Prat A, Aft RL, Ellis MJ, Piwnica-Worms H. Targeting Chk1 in p53-deficient triple-negative breast cancer is therapeutically beneficial in human-in-mouse tumor models. J Clin Invest. 2012 Apr 2.
Schootman M, Deshpande AD, Pruitt S, Aft R, Jeffe DB. Estimated effects of potential interventions to prevent decreases in self-rated health among breast cancer survivors. Ann Epidemiol. 2012 Feb.
Tran DD, Corsa CA, Biswas H, Aft RL, Longmore GD. Temporal and spatial cooperation of Snail1 and Twist1 during epithelial-mesenchymal transition predicts for human breast cancer recurrence. Mol Cancer Res. 2011 Dec.
Fisher CS, Ma CX, Gillanders WE, Aft RL, Eberlein TJ, Gao F, Margenthaler JA. Neoadjuvant chemotherapy is associated with improved survival compared with adjuvant chemotherapy in patients with triple-negative breast cancer only after complete pathologic response. Ann Surg Oncol. 2012 Jan.
Aft R, Perez JR, Raje N, Hirsh V, Saad F. Could targeting bone delay cancer progression? Potential mechanisms of action of bisphosphonates. Crit Rev Oncol Hematol. 2012 May.
Aft R. Bisphosphonates in breast cancer: antitumor effects. Clin Adv Hematol Oncol. 2011 Apr.
Liu Y, Pérez M, Schootman M, Aft RL, Gillanders WE, Jeffe DB. Correlates of fear of cancer recurrence in women with ductal carcinoma in situ and early invasive breast cancer.Breast Cancer Res Treat. 2011 Nov.
Aft R. Bisphosphonates in breast cancer: clinical activity and implications of preclinical data. Clin Adv Hematol Oncol. 2011 Mar.
Cyr A, Gillanders WE, Aft RL, Eberlein TJ, Margenthaler JA. Breast cancer in elderly women (≥ 80 years): variation in standard of care? J Surg Oncol. 2011 Mar 1.
Cyr AE, Novack D, Trinkaus K, Margenthaler JA, Gillanders WE, Eberlein TJ, Ritter J, Aft RL. Are we overtreating papillomas diagnosed on core needle biopsy? Ann Surg Oncol. 2011 Apr.