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Internal Medicine / Bone and Mineral Diseases

Roberto Civitelli, MD

Current Position
Sydney M. and Stella H. Schoenberg Professor, Medicine
Division of Bone & Mineral Diseases
Chief, Division of Bone and Mineral Diseases
Professor, Orthopaedic Surgery
Professor, Cell Biology and Physiology

Specialty Areas
Bone and Mineral Diseases
Paget's Disease of Bone
Metabolic Bone Diseases

Additional Features & Interviews with Dr. Civitelli:

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Your Health Update: Beauty from the Inside Out

Patients Seen At
Center for Advanced Medicine
Medicine Multispecialty Center
4921 Parkview Place, C, 5
St. Louis, MO  63110
Fax:   314-454-5047
View Floor Map  View Campus Map   View Driving Directions

Medicine Multispecialty Center
Medical Building Two
Barnes-Jewish West County Hospital
10 Barnes West Drive, Suite 200
Creve Coeur, MO  63141
Fax:   314-996-3087
View Campus Map   View Driving Directions

Additional Languages Spoken

Mailing Address
Washington University School of Medicine, Division of Bone & Mineral Diseases
660 South Euclid Avenue, Campus Box 8301
St. Louis, MO  63110

Areas of Clinical Interest
Diagnosis and treatment of osteoporosis, osteopenia, measurement of bone density, bone metabolism, bone disease, mineral disease, Paget's disease of bone, disorders of phosphate metabolism, hypercalcemia, hypocalcemia

Medical Education
Medical Degree: Siena University School of Medicine, Siena, Italy, 1980
Residency: Internal Medicine, Siena University, School of Medicine, Siena, Italy, 1985
Fellowship: Endocrinology & Metabolism, The Jewish Hospital of St. Louis, Missouri, 1989
Hospital Affiliations
Barnes-Jewish Hospital
Barnes-Jewish West County Hospital

Honors and Awards
Sydney M. and Stella H. Schoenberg Chair in Medicine, 2003
John M. Kinney International Award for Nutrition and Metabolism, 1992
Fuller-Albright Young Investigator Award, the American Society for Bone and Mineral Research, 1994
Elizabeth Winston Lanier Award (Kappa-Delta Award) for Outstanding Orthopedic Research, 1992

Editorial Responsibilities

Calcified Tissue International

Editorial Board:
Journal of Bone and Mineral Research

Consulting Relationships:
American Society for Bone and Mineral Research: President, 2013-2014
NIH-NIDCR Special Grants Review Committee, Permanent Member, 2010-2012
American Society for Bone and Mineral Research: Member of the Board of Councilors, 2006-09
Missouri Osteoporosis Foundation: Advisory Board Member, 1999-present
NIH-DRG:Musculoskeletal and Dental Sciences IRG: General Medicine B Study Section, Permanent Member, 1997-2001

Selected or Recent Journal Articles
Salazar VS, Zarkadis N, Huang L, Norris J, Grimston SK, Mbalaviele G, Civitelli R. Embryonic ablation of osteoblast Smad4 interrupts matrix synthesis in response to canonical Wnt signaling and causes an osteogenesis-imperfecta-like phenotype. J Cell Sci. 2013 Nov 1;126(Pt 21):4974-84.

Garfield LD, Müller DJ, Kennedy JL, Mulsant BH, Reynolds CF 3rd, Teitelbaum SL, Civitelli R, Dixon D, Todorov AA, Lenze EJ. Genetic variation in the serotonin transporter and HTR1B receptor predicts reduced bone formation during serotonin reuptake inhibitor treatment in older adults. World J Biol Psychiatry. 2013 Sep 30. [Epub ahead of print]

Shea ML, Garfield LD, Teitelbaum S, Civitelli R, Mulsant BH, Reynolds CF 3rd, Dixon D, Doré P, Lenze EJ. Serotonin-norepinephrine reuptake inhibitor therapy in late-life depression is associated with increased marker of bone resorption. Osteoporos Int. 2013 May.

Grimston SK, Watkins MP, Brodt MD, Silva MJ, Civitelli R: Enhanced periosteal and endocortical responses to axial tibial compression loading in conditional connexin43 deficient mice. PLoS One 2012.

Watkins MP, Norris JY, Grimston SK, Zhang X, Phipps RJ, Ebetino FH, Civitelli R: Bisphosphonates improve trabecular bone mass and normalize cortical thickness in ovariectomized, osteoblast connexin43 deficient mice. Bone 2012 Oct.

Greenbaum AM, Revollo LD, Woloszynek JR, Civitelli R, Link DC: N-cadherin in osteolineage cells is not required for maintenance of hematopoietic stem cells. Blood; 2012 Jul 12.

Grimston S, Goldberg DB, Watkins M, Brodt MD, Silva MJ, Civitelli R: Connexin43 deficiency reduces the sensitivity of cortical bone to the effects of muscle paralysis. J Bone Miner Res 2011; 26:2151-2160.

Garcia MN, Hildebolt CF, Miley DD, Dixon DA, Couture RA, Anderson Spearie CL, Langenwalter EM, Shannon WD, Deych E, Mueller C, Civitelli R: One-year effects of vitamin D and calcium supplementation on chronic periodontitis. J Periodontol 2011; 82:25-32.

Armamento-Villareal R, Napoli N, Diemer K, Watkins M, Civitelli R, Teitelbaum S, Novack D. Bone turnover in bone biopsies of patients with low-energy cortical fractures receiving bisphosphonates: a case series. Calcif. Tissue Int. 2009; 85:37-44.

Civitelli R, Armamento-Villareal RC, Napoli, N: Bone turnover markers: Understanding their value in clinical trials and clinical practice. Osteoporosis Int. 2009: 20:743-851.

Eisman JA, Civitelli R, Adami S, Czerwinski E, Recknor C, Prince R, Reginster JY, Zaidi M, Felsenberg D, Hughes C, Mairon N, Masanauskaite D, Reid DM, Delmas PD, Recker RR: Efficacy and tolerability of intravenous ibandronate injections in postmenopausal osteoporosis: 2-year results from the DIVA study. J Rheumatol 2008; 35:488-497.

Dobrowolski R, Sasse P, Schrickel JW, Watkins M, Kim JS, Rackauskas M, Troatz C, Ghanem A, Tiemann K, Degen J, Bukauskas FF, Civitelli R, Lewalter T, Fleischmann BK, Willecke K: The conditional connexin43G138R mouse mutant represents a new model of hereditary oculodentodigital dysplasia in humans. Hum Mol Gen 2008; 17:539-554.

Shane E, Civitelli R, Delmas PD, Drezner M, Eisman JA, Lindsay R, Lorenzo J, Miller P, Ralston S, Reid I, Siris E: Maintaining the trust of physicians and the public in the medical literature: Report of a task force in scientific publishing of clinical trials. J Bone Miner Res 2007; 22:1661-1667.

Civitelli R, Napoli N, Armamento-Villareal R: Use of intravenous bisphosphonates in osteoporosis. Curr. Osteoporosis Rep. 2007; 5:8-13.

Strumpel W, Emkey R, Civitelli R: Safety considerations with bisphosphonates for the treatment of osteoporosis. Drug Saf 2007; 30:755-763.

For more articles and abstracts, take this off-site link to the National Library of Medicine Pub Med page for Dr. Roberto Civitelli

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